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phospholipase A2, Group IID Proteins (PLA2G2D)

PLA2G2D encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Additionally we are shipping PLA2G2D Antibodies (49) and PLA2G2D Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PLA2G2D 26279 Q9UNK4
PLA2G2D 18782 Q9WVF6
Rat PLA2G2D PLA2G2D 298579  
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Top PLA2G2D Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   2 μg Log in to see 6 to 11 Days
$142.86
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated 100 μg Log in to see 11 to 13 Days
$767.80
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$936.27
Details

PLA2G2D Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for phospholipase A2, Group IID (PLA2G2D) Interaction Partners

Human phospholipase A2, Group IID (PLA2G2D) interaction partners

  1. found to induce PLA2G2D expression in mice and in human monocyte-derived macrophages

  2. sPLA(2)-IID is present at the head and midpiece in the human sperm, and its activation seems to be involved in acrosomal exocytosis.

  3. phospholipid bilayer permeabilization by the hsPLA2GIID is independent of catalytic activity.

  4. The Gly80Ser polymorphism may be associated with the body weight loss seen in chronic obstructive pulmonary disease patients. PLA2G2D-Ser (show SIGLEC1 Proteins) enhances the expression of IL-6 (show IL6 Proteins) and IL-8 (show IL8 Proteins) compared with PLA2G2D-Gly.

  5. TNF-alpha (show TNF Proteins) & IFN-gamma (show IFNG Proteins) induce gene expression of a novel secretory PLA(2 (show YWHAZ Proteins))IIDin human airway epithelial cells. The possibility that it is involved in cytokine-mediated inflammation in the respiratory tract is inferred.

  6. The GIID sPLA2 is clustered on human chromosome 1 and is differentially expressed in tissues, suggesting it has unique function.

  7. overexpression of human secretory phospholipase A2 group IIA leads to an enhanced delivery of cholesterol from phospholipolysed lipoproteins to the liver

  8. These results suggest that sPLA2-IID may be one of the susceptibility genes that contribute to body weight loss in patients with COPD (show ARCN1 Proteins).

  9. lipopolysaccharides inhibit interferon gamma-induced gene expression of secretory phospholipase A2 type IID in human monocyte-derived macrophages

  10. The distribution pattern of sPLA2S in intact spermatozoa might be an additional parameter for evaluating sperm quality

Mouse (Murine) phospholipase A2, Group IID (PLA2G2D) interaction partners

  1. found to induce PLA2G2D expression in mice and in human monocyte-derived macrophages

  2. PLA2G2D in the LNs contributed to mobilization of a pool of polyunsaturated fatty acids.

PLA2G2D Protein Profile

Protein Summary

This gene encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Phospholipase A2 family members hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce lysophospholipids and free fatty acid. This gene may be involved in inflammation and immune response, and in weight loss associated with chronic obstructive pulmonary disease. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene names and symbols associated with PLA2G2D

  • phospholipase A2, group IID (PLA2G2D)
  • phospholipase A2, group IID (Pla2g2d)
  • mGIID protein
  • PLA2IID protein
  • sPLA2-IID protein
  • sPLA2S protein
  • Splash protein

Protein level used designations for PLA2G2D

GIID sPLA2 , group IID secretory phospholipase A2 , phosphatidylcholine 2-acylhydrolase 2D , secretory phospholipase A2s , secretory-type PLA, stroma-associated homolog , PLA2IID , sPLA2-IID

GENE ID SPECIES
26279 Homo sapiens
18782 Mus musculus
298579 Rattus norvegicus
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