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phospholipase A2, Group V Proteins (PLA2G5)

PLA2G5 is a member of the secretory phospholipase A2 family. Additionally we are shipping PLA2G5 Antibodies (57) and PLA2G5 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PLA2G5 18784 P97391
PLA2G5 5322 P39877
PLA2G5 29354 P51433
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Top PLA2G5 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Rat His tag phospholipase A2, Group V (PLA2G5) (AA 21-137) protein (His tag) expressed in E. coli 1 mg Log in to see 56 to 66 Days
$2,227.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   2 μg Log in to see 6 to 11 Days
$142.86
Details

PLA2G5 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,
Rat (Rattus)

More Proteins for phospholipase A2, Group V (PLA2G5) Interaction Partners

Mouse (Murine) phospholipase A2, Group V (PLA2G5) interaction partners

  1. GV sPLA2 (show PLA2G2A Proteins) is involved in the maintenance of tubular cell function and integrity, promoting sodium retention through increased cortical (Na+ + K+)-ATPase (show ATP1A1 Proteins) expression and activity.

  2. AdPLA2 plays an important role in promoting tumorigenesis and disease progression by modulating the production of prostaglandins and may serve as a potential therapeutic target in TSC (show SLC12A3 Proteins) and LAM (show LSAMP Proteins).

  3. PLA2G5 hydrolyzed phosphatidylcholine (show SGMS2 Proteins) in fat-overladen low-density lipoprotein to release unsaturated fatty acids, which prevented palmitate-induced M1 macrophage polarization.

  4. Key Data shows the role of group v secreted phospholipase A2 (show YWHAZ Proteins) in Th2 cytokine and dendritic cell-driven airway hyperresponsiveness and remodeling.

  5. Our studies identified a unique function of gV-sPLA2 (show PLA2G2A Proteins) in activation of macrophages

  6. The impact of group V sPLA(2 (show PLA2G2A Proteins)) deficiency on angiotensin (Ang) II (show AGT Proteins)-induced cardiac fibrosis in apoE (show APOE Proteins) deficient mice was investigated.

  7. The results indicate that the PLA(2) activity also plays a substantial role in protecting cells against oxidant stress caused by an exogenous hydroperoxide.

  8. GV sPLA(2 (show PLA2G2A Proteins)) in bone marrow-derived myeloid cells as well as non-myeloid cells, which are likely bronchial epithelial cells, participate in the regulation of the innate immune response to pulmonary infection with E. coli.

  9. Data from cuprizone-induced model of multiple sclerosis suggest that sPLA2 down-regulation during remyelination can limit release of AA and consequent production of pro-inflammatory PGs/TXB2 (which are increased during demyelination).

  10. sPLA(2 (show PLA2G2A Proteins))-V plays an important role in the pathogenesis of myocardial ischemia reperfusion injury partly in concert with the activation of cPLA(2 (show PLA2G4A Proteins))

Human phospholipase A2, Group V (PLA2G5) interaction partners

  1. The clinical findings in this family suggest a diagnosis of benign familial fleck retina with excellent prognosis, in which the PLA2G5 gene may play a role.

  2. sPLA2 (show PLA2G2A Proteins)-V plays a thrombogenic role by impairing the ability of EPCR (show PROCR Proteins) to promote protein C activation.

  3. results demonstrate that EPCR (show PROCR Proteins) is overexpressed and mediates the aggressive behavior of rheumatoid synovial fibroblasts, and is likely driven by group V secretory phospholipase A2 (show YWHAZ Proteins)

  4. expression of PLA2s (show PLA2G2A Proteins)-IIE and -V correlates with the development of calcification as well as the expression of pro-osteogenic molecules in human aortic valves

  5. Summarizing, Der (show GDF3 Proteins) p1 and Fel (show CREB3L2 Proteins) d1 involve phospholipase A2 (show YWHAZ Proteins) enzymes in their action.

  6. There is no association between rs525380 polymorphism of PLA2G5 and coronary heart disease.

  7. Our results demonstrate the association of the PLA2G5 rs11573191 polymorphism with premature CAD. In our study, it was possible to distinguish one haplotype associated with increased risk of premature CAD and hypertension.

  8. Human group V secretory phospholipase A2 (show YWHAZ Proteins) is associated with lipid rafts and internalized in a flotillindependent pathway.

  9. Our studies identified a unique function of gV-sPLA2 (show PLA2G2A Proteins) in activation of macrophages

  10. The effects of acidic pH on the activity of recombinant human group V secreted phospholipase A (show HRASLS Proteins)(2) (sPLA(2 (show PLA2G2A Proteins))-V) toward small VLDL (sVLDL), IDL, and LDL, on the binding of these apoB-100 (show APOB Proteins)-containing lipoproteins to human aortic proteoglycans, were examined.

PLA2G5 Protein Profile

Protein Summary

This gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their full-length nature has not been determined.

Gene names and symbols associated with PLA2G5

  • phospholipase A2, group V (PLA2G5)
  • phospholipase A2, group V (Pla2g5)
  • FRFB protein
  • GV-PLA2 protein
  • hVPLA(2) protein
  • PLA2 protein
  • PLA2-10 protein
  • sPLA2 protein

Protein level used designations for PLA2G5

calcium-dependent phospholipase A2 , phospholipase A2, group V , PLA2-10 , group V phospholipase A2 , phosphatidylcholine 2-acylhydrolase 5 , Ca2+-dependent phospholipase A2 , phospholipase A2, group 5

GENE ID SPECIES
614911 Bos taurus
456588 Pan troglodytes
478207 Canis lupus familiaris
771655 Gallus gallus
18784 Mus musculus
5322 Homo sapiens
29354 Rattus norvegicus
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