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phospholipase A2, Group VII (Platelet-Activating Factor Acetylhydrolase, Plasma) Proteins (PLA2G7)

The protein encoded by PLA2G7 is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Additionally we are shipping PLA2G7 Antibodies (16) and PLA2G7 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PLA2G7 7941 Q13093
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Top PLA2G7 Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
HOST_HEK293 Human Un-conjugated 20 μg Log in to see 7 to 9 Days
$328.21
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 500 μg Log in to see 3 to 4 Days
$735.00
Details

PLA2G7 Proteins by Origin and Source

Origin Expressed in
Human ,

More Proteins for phospholipase A2, Group VII (Platelet-Activating Factor Acetylhydrolase, Plasma) (PLA2G7) Interaction Partners

Human phospholipase A2, Group VII (Platelet-Activating Factor Acetylhydrolase, Plasma) (PLA2G7) interaction partners

  1. PLA2G7 (show Lp-PLA2 Proteins) gene expression was co-regulated by 17-beta-estradiol and promoter methylation.

  2. Lp-PLA2 (show Lp-PLA2 Proteins) activity in Japanese men aged 50-79 years was associated significantly and positively with IMT and plaque in the carotid artery but Mendelian randomization did not support that Lp-PLA2 (show Lp-PLA2 Proteins) is a causative factor for subclinical atherosclerosis.

  3. 279Val-->Phe Polymorphism of Lp-PLA2 (show Lp-PLA2 Proteins) may lead to decrease the enzymatic activity via changes of folding kinetics and recognition to its substrate.

  4. Increased plasma Lp-PLA2 (show Lp-PLA2 Proteins) activity portends increased risk of resistant hypertension.

  5. These findings suggest that plasma PAF (show KIAA0101 Proteins) may be a potential biomarker for predicting poor bone health in postmenopausal women.

  6. Studied whether the level of Lp-PLA2 (show Lp-PLA2 Proteins) is associated with subclinical atherosclerosis in patients with rheumatoid arthritis.

  7. Higher Lp-PLA2 (show Lp-PLA2 Proteins) mass and activity were associated with development of both incident clinical peripheral arterial disease and low ankle brachial index.

  8. A V279F loss-of-function variant in the PLA2G7 (show Lp-PLA2 Proteins) gene resulting in 50% lower activity for each copy of the variant, is common in East Asians and associated with risk of Vascular diseases.

  9. It is assumed that Lp-PLA2 (show Lp-PLA2 Proteins) is involved in vascular calcification and that dp-ucMGP is a more appropriate biomarker of residual risk than Lp-PLA2 (show Lp-PLA2 Proteins) itself.

  10. Cytosolic phospholipase A2 modulates TLR2 signaling in synoviocytes.

PLA2G7 Protein Profile

Protein Summary

The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with PLA2G7

  • phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) (PLA2G7)
  • phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) (Pla2g7)
  • LDL-PLA2 protein
  • LP-PLA2 protein
  • PAFAD protein
  • PAFAH protein

Protein level used designations for PLA2G7

1-alkyl-2-acetylglycerophosphocholine esterase , 2-acetyl-1-alkylglycerophosphocholine esterase , LDL-PLA(2) , LDL-associated phospholipase A2 , PAF 2-acylhydrolase , PAF acetylhydrolase , platelet-activating factor acetylhydrolase , plasma PAF acetylhydrolase , Paf-acetylhydrolase , gVIIA-PLA2 , group-VIIA phospholipase A2 , lipoprotein-associated phospholipase A2

GENE ID SPECIES
282311 Bos taurus
395816 Gallus gallus
403848 Canis lupus familiaris
100135600 Cavia porcellus
7941 Homo sapiens
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