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phospholipase A2 Receptor 1, 180kDa Proteins (PLA2R1)

PLA2R1 represents a phospholipase A2 receptor. Additionally we are shipping PLA2R1 Antibodies (45) and PLA2R1 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PLA2R1 18779 Q62028
PLA2R1 22925 Q13018
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Top PLA2R1 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 69 to 74 Days
$9,050.32
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 69 to 74 Days
$12,906.52
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PLA2R1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , , ,
,

More Proteins for phospholipase A2 Receptor 1, 180kDa (PLA2R1) Interaction Partners

Mouse (Murine) phospholipase A2 Receptor 1, 180kDa (PLA2R1) interaction partners

  1. Study showed that CTLD1-2 as well as the FNII domain of PLA2R were responsible for binding to collagen I and collagen-dependent migration in both mouse and human PLA2R.

  2. PLA2R might play a pathogenic role in myocardial infarction of PLA2R-deficient mice, through impaired healing of the infarcted region.

  3. PLA2R deficiency increased sPLA2 (show PLA2G2A Proteins)-IB and -X levels in the lung through their impaired clearance from the lung, leading to exaggeration of lung inflammation induced by OVA treatment in a murine model.

Human phospholipase A2 Receptor 1, 180kDa (PLA2R1) interaction partners

  1. Accordingly, PLA2R ABs assay seems to be promising tool not only to diagnose MN but also to predict the course of the disease and could open the way to personalize therapy. [review]

  2. PLA2R1 expression in breast cancer cells is controlled by DNA methylation (show HELLS Proteins) and histone modifications

  3. Assessments of both serum PLA2R antibodies and PLA2R antigen in glomeruli were more sensitive for the diagnosis of PLA2R-related membranous nephropathy

  4. Data indicate that enhanced granular expression of phospholipase A2 (show YWHAZ Proteins) receptor (PLA2R) and thrombospondin type-1 domain-containing 7A (THSD7A (show THSD7A Proteins)) was detected in 9.1% and 52.7%, respectively, of the patients with idiopathic membranous nephropathy (MN).

  5. Anti-PLA2R antibodies were found in Japanese patients with idiopathic membranous nephropathy; however, the prevalence was lower than that of any other Asian country.

  6. Suggest that PLA2R has a contributory role in the pathogenesis of paediatric idiopathic membranous nephropathy.

  7. Renal biopsy PLA2R positivity was common in idiopathic membranous nephropathy (MN) and HBV-MN but rare in lupus-associated MN, and it was closely associated with serum PLA2R-Ab production.

  8. Case Report: PLA2R positive membranous nephropathy in kidney transplant recipient with both IgA nephropathy and HCV infection long after kidney transplant from identical twin.

  9. The detection and measurement of PLA2R-AB in idiopathic membranous nephropathy patients may be important tool in monitoring of the disease and efficacy of the treatment.

  10. serological anti-PLA2R testing has diagnostic value for differentiating iMN from sMN (show STMN1 Proteins), but it must be interpreted in context with patient clinical characteristics (degree of proteinuria, immunosuppressive treatment, time of detection).

PLA2R1 Protein Profile

Protein Summary

This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with PLA2R1

  • phospholipase A2 receptor 1, 180kDa (LOC100229329)
  • phospholipase A2 receptor 1 (Pla2r1)
  • phospholipase A2 receptor 1, 180kDa (PLA2R1)
  • CLEC13C protein
  • PLA2-R protein
  • Pla2g1br protein
  • PLA2G1R protein
  • PLA2IR protein
  • PLA2R protein

Protein level used designations for PLA2R1

phospholipase A2 receptor 1, 180kDa , 180 kDa secretory phospholipase A2 receptor , M-type receptor , PLA2-I receptor , phospholipase A2, group IB, pancreas, receptor , secretory phospholipase A2 receptor , C-type lectin domain family 13 member C , PLA2-R , PLA2R

GENE ID SPECIES
100229329 Taeniopygia guttata
18779 Mus musculus
22925 Homo sapiens
317777 Bos taurus
100009180 Oryctolagus cuniculus
100173143 Pongo abelii
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