anti-phosphoprotein Enriched in Astrocytes 15 (PEA15) Antibodies

PEA15 encodes a death effector domain-containing protein, which is a major phosphoprotein in astrocytes, and an endogenous substrate for protein kinase C. Additionally we are shipping PEA15 Proteins (11) and PEA15 Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PEA15 8682 Q15121
PEA15 18611 Q62048
PEA15 364052 Q5U318
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Top anti-PEA15 Antibodies at antibodies-online.com

Showing 10 out of 111 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-PEA15 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>721_B cell lysate WB Suggested Anti-PEA15 Antibody <br /> Positive Control: Lane 1:241 µg EGFP-transfected MCF7 lysate Lane 2: 041 µg EGFP-PEA15 transfected MCF7 lysate <br />Primary Antibody Dilution: 1:0000<br />Secondary Antibody: Goat anti-rabbit-HRP Secondry <br /> Antibody Dilution: 1:0000<br />Submitted by: Yann Wallez (Sanford-Burnham Medical Research Institute) 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-PEA15 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Human brain WB Suggested Anti-PEA15 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Human brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of MCF7 cells, using PEA15 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from COS7 cells treated with TNF 20ng/ml 5', using PEA-15 (Phospho-Ser104) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human heart, using PEA-15 (Phospho-Ser104) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of PEA-15 Antibody (C-term) (ABIN652463) in T47D cell line lysates (35 µg/lane).PEA-15 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of PEA-15 Antibody (C-term) (ABIN652463) in mouse lung tissue lysates (35 µg/lane).PEA-15 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB (LEFT) Western blot analysis of PEA-15 Antibody (C-term) in T47D cell line lysates (35ug/lane).PEA-15 (arrow) was detected using the purified Pab. (RIGHT) Western blot analysis of PEA-15 Antibody (C-term) in mouse lung tissue lysates (35ug/lane).PEA-15 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, treated with PMA 125ng/ml 30', using PEA-15 (Ab-116) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PEA-15 (Ab-116) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human heart tissue, using PEA-15 (Ab-104) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from COS7 cells treated with INSULIN 0.01U/ML 15', using PEA-15 (Phospho-Ser116) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human skeletal muscle, using PEA-15 (Phospho-Ser116) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details

PEA15 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PEA15 Antibodies

  1. Human Polyclonal PEA15 Primary Antibody for FACS, IHC (p) - ABIN652463 : Trencia, Perfetti, Cassese, Vigliotta, Miele, Oriente, Santopietro, Giacco, Condorelli, Formisano, Beguinot: Protein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic action. in Molecular and cellular biology 2003 (PubMed)
    Show all 3 Pubmed References

More Antibodies against PEA15 Interaction Partners

Human phosphoprotein Enriched in Astrocytes 15 (PEA15) interaction partners

  1. PP4 (show ANXA5 Antibodies) regulates breast cancer cell survival and identifies a novel PP4c (show PPP4C Antibodies)-PEA15 signalling axis in the control of breast cancer cell survival.

  2. PEA15 expression was not significantly correlated with ovarian cancer antineoplastic drug resistance.

  3. Data suggest the role of the phospholipase C epsilon (show PLCL1 Antibodies)-Protein kinase D (show PRKD1 Antibodies)-PEA15 protein-ribosomal S6 kinase (show RPS6KB1 Antibodies)-IkappaB-NF-kappa B (show NFKB1 Antibodies) pathway in facilitating inflammation and inflammation-associated carcinogenesis in the colon.

  4. Integrin alpha5beta1 and p53 (show TP53 Antibodies) convergent pathways in the control of anti-apoptotic proteins PEA-15 and survivin (show BIRC5 Antibodies) in high-grade glioma.

  5. High PED expression is associated with esophageal carcinoma.

  6. The nuclear translocation of SApErk1/ 2 apart from PEA-15 as an important mechanism to reverse senescence phenotype.

  7. Latent HCMV infection of CD34 (show CD34 Antibodies) + cells protects cells from FAS (show FAS Antibodies)-mediated apoptosis through the cellular IL-10 (show IL10 Antibodies)/PEA-15 pathway.

  8. New therapeutic targets based around PEA-15 and its associated interactions are now being uncovered and could provide novel avenues for treatment strategies in multiple diseases.

  9. PED/PEA-15 overexpression is sufficient to block hydrogen peroxide-induced apoptosis in Ins-1E cells through a PLD-1 mediated mechanism

  10. Omi/HtrA2 (show HTRA2 Antibodies) overexpression promotes hepatocellular carcinoma cell apoptosis and the ped/pea-15 expression level causes this difference of the Omi/HtrA2 (show HTRA2 Antibodies) pro-apoptotic marker in the various hepatocellular carcinoma cell lines

Mouse (Murine) phosphoprotein Enriched in Astrocytes 15 (PEA15) interaction partners

  1. Data suggest that PEA-15 contributes to the specification of the cytokine pattern of activated Th cells, thus highlighting a potential new target to interfere with T cell functional polarization and subsequent immune response.

  2. PED/PEA-15 overexpression is sufficient to block hydrogen peroxide-induced apoptosis in Ins-1E cells through a PLD-1 mediated mechanism

  3. Activated astrocytes are known to clear the Abeta (show APP Antibodies) deposited in the extracellular milieu, which is why they play a key role in regulating the progression of Alzheimer's disease (AD).

  4. Activation of peroxisome proliferator-activated receptor-gamma (PPARgamma (show PPARG Antibodies)) represses transcription of the ped/pea-15 gene.

  5. The findings revealed a novel mechanism by which PEA-15 positively regulates Ras/ERK signaling and increases the proliferation of H-Ras-transformed epithelial cells through enhanced phospholipase D1 expression and activation.

  6. PEA-15 did not differentiate and showed markedly enhanced autophagy. In these same cells, the autophagy inhibitor 3 (show PPP1R11 Antibodies)-methyladenine rescued TGF-beta1 (show TGFB1 Antibodies) effect on both autophagy and myogenesis, indicating that PEA-15 mediates TGF-beta1 (show TGFB1 Antibodies) effects in muscle.

  7. Data suggest that PED/PEA-15 may affect fibroblast motility by a mechanism, at least in part, mediated by ERK1/2 (show MAPK1/3 Antibodies).

  8. we propose that PEA-15 represents a novel point of convergence of the protein kinas C and MAPK/ERK (show MAPK1 Antibodies) pathways under gonadotropin releasing hormone stimulation

  9. PEA-15 regulates T-cell proliferation

  10. PEA-15 inhibits tumorigenesis in an MDA-MB-468 triple-negative breast cancer xenograft model through increased cytoplasmic localization of activated extracellular signal-regulated kinase.

PEA15 Antigen Profile

Protein Summary

This gene encodes a death effector domain-containing protein, which is a major phosphoprotein in astrocytes, and an endogenous substrate for protein kinase C. Studies using knockout mice suggest that this protein may protect astrocytes from TNF-induced apoptosis. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake.

Gene names and symbols associated with PEA15

  • proliferation and apoptosis adaptor protein 15 (PEA15) antibody
  • phosphoprotein enriched in astrocytes 15A (Pea15a) antibody
  • proliferation and apoptosis adaptor protein 15 (Pea15) antibody
  • phosphoprotein enriched in astrocytes 15 (PEA15) antibody
  • proliferation and apoptosis adaptor protein 15 L homeolog (pea15.L) antibody
  • proliferation and apoptosis adaptor protein 15 (pea15) antibody
  • Astrocytic phosphoprotein PEA-15 (pea15) antibody
  • phosphoprotein enriched in astrocytes 15 (pea15) antibody
  • DKFZp459O1410 antibody
  • HMAT1 antibody
  • HUMMAT1H antibody
  • Mat1 antibody
  • MAT1H antibody
  • PEA-15 antibody
  • PEA15 antibody
  • Pea15a antibody
  • PED antibody
  • Pkcs15 antibody

Protein level used designations for PEA15

15 kDa phosphoprotein enriched in astrocytes , Phosphoprotein enriched in astrocytes, 15kD , astrocytic phosphoprotein PEA-15 , homolog of mouse MAT-1 oncogene , phosphoprotein enriched in diabetes , mammary transforming gene 1 , phosphoprotein enriched in astrocytes 15 , phosphoprotein enriched in astrocytes 15A , Astrocytic phosphoprotein PEA-15

GENE ID SPECIES
8682 Homo sapiens
18611 Mus musculus
364052 Rattus norvegicus
510586 Bos taurus
610113 Canis lupus familiaris
705026 Macaca mulatta
734852 Xenopus laevis
100145359 Xenopus (Silurana) tropicalis
100152480 Sus scrofa
100174153 Pongo abelii
100286636 Salmo salar
100730336 Cavia porcellus
557745 Danio rerio
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