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phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase Proteins (PAICS)

PAICS encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. Additionally we are shipping PAICS Antibodies (64) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PAICS 10606 P22234
PAICS 140946 P51583
PAICS 67054 Q9DCL9
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Top PAICS Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,182.67
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$3,182.67
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,188.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 14 to 16 Days
$329.18
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PAICS Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Mouse (Murine)

More Proteins for phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS) Interaction Partners

Zebrafish phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS) interaction partners

  1. Two recessive zebrafish mutations that affect de novo purine synthesis, gart (show GART Proteins) and paics, were analyzed.

Human phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS) interaction partners

  1. purine biosynthetic pathway enzymes PPAT and PAICS, as well as pyruvate kinase activity are increased in lung cancer

PAICS Protein Profile

Protein Summary

This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PAICS

  • phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (PAICS)
  • phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (paics)
  • multifunctional protein ADE2 (ade5)
  • multifunctional protein ADE2 (Tsp_02239a)
  • multifunctional protein ADE2 (Tsp_02239)
  • phosphoribosylaminoimidazole carboxylase (CNE02500)
  • phosphoribosylaminoimidazole carboxylase (purC/E)
  • phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (Paics)
  • phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, gene 2 (paics.2)
  • phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase (Paics)
  • 2610511I09Rik protein
  • ade2 protein
  • Ade2h1 protein
  • airc protein
  • AS protein
  • cb293 protein
  • DDBDRAFT_0218550 protein
  • DDBDRAFT_0230088 protein
  • DDB_0218550 protein
  • DDB_0230088 protein
  • GB14262 protein
  • paics protein
  • pais protein
  • sb:cb293 protein
  • wu:fa28a05 protein

Protein level used designations for PAICS

multifunctional protein ADE2 , phosphoribosylaminoimidazole carboxylase , phosphoribosylaminoimidazolesuccinocarboxamide synthase , AIR carboxylase domain , AIR carboxylase , SAICAR synthetase , multifunctional protein ADE2H1 , phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole succinocarboxamide synthetase , Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase

GENE ID SPECIES
100058501 Equus caballus
321193 Danio rerio
551966 Apis mellifera
10907789 Trichinella spiralis
10907827 Trichinella spiralis
3257629 Cryptococcus neoformans var. neoformans JEC21
8624324 Dictyostelium discoideum AX4
396534 Gallus gallus
10606 Homo sapiens
404170 Bos taurus
140946 Rattus norvegicus
475150 Canis lupus familiaris
100521281 Sus scrofa
100190835 Pongo abelii
431975 Xenopus laevis
67054 Mus musculus
Selected quality suppliers for PAICS Proteins (PAICS)
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