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proline/serine-Rich Coiled-Coil 1 Proteins (PSRC1)

PSRC1 encodes a proline-rich protein. Additionally we are shipping proline/serine-Rich Coiled-Coil 1 Antibodies (39) and proline/serine-Rich Coiled-Coil 1 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PSRC1 84722 Q6PGN9
PSRC1 56742 Q9D0P7
PSRC1 691380 Q3KR66
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Top proline/serine-Rich Coiled-Coil 1 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,876.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,887.50
Details

PSRC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced proline/serine-Rich Coiled-Coil 1 Proteins

  1. Human PSRC1 Protein expressed in Wheat germ - ABIN1316679 : Mangé, Lacombe, Bascoul-Mollevi, Jarlier, Lamy, Rouanet, Maudelonde, Solassol: Serum autoantibody signature of ductal carcinoma in situ progression to invasive breast cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2012 (PubMed)

More Proteins for proline/serine-Rich Coiled-Coil 1 (PSRC1) Interaction Partners

Human proline/serine-Rich Coiled-Coil 1 (PSRC1) interaction partners

  1. no association was found between the SNPs of rs599839, rs464218 and rs6698843 at the CELSR2 (show CELSR2 Proteins)-PSRC1-SORT1 (show SORT1 Proteins) and the risk of coronary artery disease or ischemic stroke

  2. Thus, ANKRD53 is recruited to the mitotic spindle by DDA3 and acts as a regulator of spindle dynamics and cytokinesis.

  3. Thus, our findings identified a definite regulatory mechanism of the search and capture process for stable spindle attachment through cross-talk between spindle dynamics and KT composition mediated by DDA3 and Ska1 (show SKA1 Proteins).

  4. DDA3 controls astral spindle formation and spindle positioning by targeting Cep290 to the centrosome. Depletion of Cep290 caused a reduction of the astral spindle, leading to misorientation of the mitotic spindle.

  5. PSRC1 in the cholesterol gene cluster shows a significant association with coronary artery disease and its single nucleotide polymorphism regulates plasma cholesterol levels.

  6. Thus, the EB1 (show MAPRE2 Proteins)-based function of DDA3 links MT dynamics to directional cell migration

  7. kinases control the function of DDA3 in the cell cycle by regulating its microtubules-polymerizing/bundling activities through sequential phosphorylation.

  8. MCAK (show KIF2C Proteins) and CENP-E (show CENPE Proteins) are involved in DDA3-mediated chromosome congression.

  9. the mitotic function of DDA3 is regulated by phosphorylation on the Ser225 residue.

  10. The C-terminal domain confers its ability to associate with the mitotic spindle, while the regulatory N-terminal domain controls the microtubule-binding by the C-terminal domain and determines the cellular activity of the DDA3 protein.

Mouse (Murine) proline/serine-Rich Coiled-Coil 1 (PSRC1) interaction partners

  1. A p53 (show TP53 Proteins) response element mediates transcriptional activation

  2. DDA3 is a novel microtubule-associated protein (show SPAG5 Proteins) that binds to EB3 (show MAPRE3 Proteins), and results implicate DDA3 and EB3 (show MAPRE3 Proteins) in the beta-catenin (show CTNNB1 Proteins)-mediated growth signaling.

proline/serine-Rich Coiled-Coil 1 (PSRC1) Protein Profile

Protein Summary

This gene encodes a proline-rich protein. Studies of this gene and the related mouse gene suggest that this gene is regulated by p53 and may participate in p53-mediated growth suppression. The encoded protein may function as a microtubule destabilizing protein that controls spindle dynamics and mitotic progression by recruiting and regulating microtubule depolymerases. At least one genetic variation in this gene has been associated with decreased serum levels of low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with PSRC1

  • proline/serine-rich coiled-coil 1 (PSRC1)
  • proline/serine-rich coiled-coil 1 (Psrc1)
  • 5430413I02Rik protein
  • AL033312 protein
  • Dda3 protein
  • FP3214 protein

Protein level used designations for PSRC1

differential display and activated by p53 , p53-regulated DDA3 , proline/serine-rich coiled-coil protein 1

GENE ID SPECIES
84722 Homo sapiens
56742 Mus musculus
691380 Rattus norvegicus
541250 Bos taurus
611844 Canis lupus familiaris
100156693 Sus scrofa
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