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Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. Additionally we are shipping GRAF Antibodies (89) and GRAF Proteins (5) and many more products for this protein.
We conclude that a transient interaction between Cdc42 (show CDC42 ELISA Kits) and GRAF1 drives endocytic turnover and controls the transition essential for endosomal maturation of plasma membrane internalised by this mechanism.
GRAF expression is a favorable prognostic marker in patients with acute myeloid leukemia (show BCL11A ELISA Kits).
ADAR1 (show ADAR ELISA Kits) regulates the expression of ARHGAP26 through A-to-I RNA editing by disrupting the binding of miR (show MLXIP ELISA Kits)-30b-3p and miR (show MLXIP ELISA Kits)-573 within the 3' UTR (show UTS2R ELISA Kits) of ARHGAP26.
proposed that GRAF1 remodels membrane microdomains at adhesion sites into endocytic carriers, facilitating membrane turnover during cell morphological changes
Findings suggest that the hypermethylation of GRAF promoter might be one of early events in the development of AML (show RUNX1 ELISA Kits).
a GTPase-activating protein (show RASA1 ELISA Kits) that regulates muscle maturation and to highlight the functional importance of BAR domains in myotube formation
Decreased level of GRAF transcript is associated with acute myeloid leukemia (show BCL11A ELISA Kits), myelodysplastic syndrome and chronic myeloid leukemia (show BCL11A ELISA Kits).
The GRAF gene was down-regulated in AML (show RUNX1 ELISA Kits), which might play a role in the leukemogenesis.
The analysis of the expression pattern of the GRAF1/OPHN-1 (show OPHN1 ELISA Kits)-L gene in human tissues and organs revealed the predominant brain expression of a novel splicing isoform.
abnormal GRAF methylation might be an adverse prognostic event in MDS (show PAFAH1B1 ELISA Kits)
Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene.
Rho GTPase activating protein 26
, rho GTPase-activating protein 26-like
, GTPase regulator associated with focal adhesion kinase pp125(FAK)
, oligophrenin-1-like protein
, rho GTPase-activating protein 26
, rho-type GTPase-activating protein 26
, GTPase regulator associated with focal adhesion kinase
, rhoGap protein