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rho GTPase Activating Protein 26 Proteins (ARHGAP26)

Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. Additionally we are shipping GRAF Antibodies (86) and GRAF Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ARHGAP26 23092 Q9UNA1
ARHGAP26 71302 Q6ZQ82
Rat ARHGAP26 ARHGAP26 307459  
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Top GRAF Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ARHGAP26 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced GRAF Proteins

  1. Human GRAF Protein expressed in Wheat germ - ABIN1345506 : Jarius, Scharf, Begemann, Stöcker, Probst, Serysheva, Nagel, Graus, Psimaras, Wildemann, Komorowski: Antibodies to the inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) in cerebellar ataxia. in Journal of neuroinflammation 2015 (PubMed)
    Show all 2 references for ABIN1345506

More Proteins for rho GTPase Activating Protein 26 (ARHGAP26) Interaction Partners

Human rho GTPase Activating Protein 26 (ARHGAP26) interaction partners

  1. We conclude that a transient interaction between Cdc42 (show CDC42 Proteins) and GRAF1 drives endocytic turnover and controls the transition essential for endosomal maturation of plasma membrane internalised by this mechanism.

  2. GRAF expression is a favorable prognostic marker in patients with acute myeloid leukemia (show BCL11A Proteins).

  3. ADAR1 (show ADAR Proteins) regulates the expression of ARHGAP26 through A-to-I RNA editing by disrupting the binding of miR (show MLXIP Proteins)-30b-3p and miR (show MLXIP Proteins)-573 within the 3' UTR of ARHGAP26.

  4. proposed that GRAF1 remodels membrane microdomains at adhesion sites into endocytic carriers, facilitating membrane turnover during cell morphological changes

  5. Findings suggest that the hypermethylation of GRAF promoter might be one of early events in the development of AML (show RUNX1 Proteins).

  6. a GTPase-activating protein (show RASA1 Proteins) that regulates muscle maturation and to highlight the functional importance of BAR domains in myotube formation

  7. Decreased level of GRAF transcript is associated with acute myeloid leukemia (show BCL11A Proteins), myelodysplastic syndrome and chronic myeloid leukemia (show BCL11A Proteins).

  8. The GRAF gene was down-regulated in AML (show RUNX1 Proteins), which might play a role in the leukemogenesis.

  9. The analysis of the expression pattern of the GRAF1/OPHN-1 (show OPHN1 Proteins)-L gene in human tissues and organs revealed the predominant brain expression of a novel splicing isoform.

  10. abnormal GRAF methylation might be an adverse prognostic event in MDS (show PAFAH1B1 Proteins)

GRAF (ARHGAP26) Protein Profile

Protein Summary

Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ARHGAP26

  • Rho GTPase activating protein 26 (ARHGAP26)
  • Rho GTPase activating protein 26 (Arhgap26)
  • 1810044B20Rik protein
  • 2610010G17Rik protein
  • 4933432P15Rik protein
  • AI853435 protein
  • ARHGAP26 protein
  • GRAF protein
  • GRAF1 protein
  • mKIAA0621 protein
  • OPHN1L protein
  • OPHN1L1 protein

Protein level used designations for ARHGAP26

Rho GTPase activating protein 26 , rho GTPase-activating protein 26-like , GTPase regulator associated with focal adhesion kinase pp125(FAK) , oligophrenin-1-like protein , rho GTPase-activating protein 26 , rho-type GTPase-activating protein 26 , GTPase regulator associated with focal adhesion kinase , rhoGap protein

GENE ID SPECIES
538219 Bos taurus
706084 Macaca mulatta
100393728 Callithrix jacchus
100436890 Pongo abelii
100484916 Ailuropoda melanoleuca
478046 Canis lupus familiaris
23092 Homo sapiens
71302 Mus musculus
307459 Rattus norvegicus
396113 Gallus gallus
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