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GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity). Additionally we are shipping ARHGAP36 Antibodies (29) and many more products for this protein.
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We have reported here for the first time a reduced activity of both Rac1 and Cdc42 (show CDC42 Proteins) in human pheochromocytoma resection as well as tumor-associated expression changes of FARP1 (show FARP1 Proteins), ARHGEF1 (show ARHGEF1 Proteins), and ARHGAP36
ARHGAP36 isoforms capable of Gli activation are up-regulated in a subset of human medulloblas (show GLI1 Proteins)tomas.
Arhgap36 acts in a Smoothened-independent manner to promote the activation of full-length Gli (show GLI1 Proteins) proteins and induces the accumulation of Gli (show GLI1 Proteins) proteins in the primary cilium. Its ability to induce Gli (show GLI1 Proteins)-dependent transcription requires kinesin family member 3a (show KIF3A Proteins) and intraflagellar transport protein 88, proteins that are essential for ciliogenesis. Arhgap36 functionally and biochemically interacts with Suppressor of Fused (show SUFUH Proteins).
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state (By similarity).
rho GTPase-activating protein 36
, Novel RhoGAP domain containing protein
, Rho-GTPase-activating protein like protein
, Rho GTPase-activating protein 36