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Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. Additionally we are shipping rho Guanine Nucleotide Exchange Factor (GEF) 15 Proteins (3) and many more products for this protein.
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Human Polyclonal ARHGEF15 Primary Antibody for IHC - ABIN965590
Nagase, Ishikawa, Suyama, Kikuno, Hirosawa, Miyajima, Tanaka, Kotani, Nomura, Ohara: Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. in DNA research : an international journal for rapid publication of reports on genes and genomes 1999
Arhgef15 acts as an endothelial cell-specific GEF to mediate VEGF-induced Cdc42 activation and potentiate RhoJ inactivation, thereby promoting actin polymerization and cell motility.
Study identified a RhoA (show RHOA Antibodies) guanine nucleotide exchange factor (show ARHGEF12 Antibodies), Ephexin5, which negatively regulates excitatory synapse development until EphrinB binding to the EphB receptor triggers Ephexin5 phosphorylation, ubiquitination, and degradation.[Ephexin5]
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. This gene encodes a protein that functions as a specific guanine nucleotide exchange factor for RhoA. It also interacts with ephrin A4 in vascular smooth muscle cells. Two alternatively spliced transcripts variants that encode the same protein have been found for this gene.
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, Rho guanine nucleotide exchange factor (GEF) 15
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, Rho GEF 15
, Rho guanine exchange factor (GEF) 15