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ARHGEF26 encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. Additionally we are shipping and many more products for this protein.
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The guanine-nucleotide exchange factor (show ARHGEF12 Antibodies) SGEF plays a crucial role in the formation of atherosclerosis.
Data support evidence for SGEF role in both the promotion of cell invasion and cell survival signaling within glioblastoma tumors and promoting chemotherapeutic resistance.
A novel function of SGEF that excludes GEF (show SLC2A4RG Antibodies).
We report for the first time an SGEF function for RhoG (show RHOG Antibodies) that excludes GEF (show SLC2A4RG Antibodies) and the ability of SGEF to enhance EGFR (show EGFR Antibodies) stability and signaling by delaying its lysosomal sorting and degradation
Data indicate that the Src (show SRC Antibodies) homology 3 domain-containing GEF (show SLC2A4RG Antibodies) (SGEF) promotes fibroblast growth factor-inducible 14 (show DDX3X Antibodies) (Fn14 (show TNFRSF12A Antibodies)) proinvasive signaling in glioblastoma via TNF receptor-associated factor 2 (TRAF2 (show TRAF2 Antibodies)).
SGEF is a novel promoter of human prostate cancer progression and development.
The invasive capacity of HPV transformed cells requires the hDlg-dependent enhancement of SGEF/RhoG activity.
SGEF gene on chromosome 3q25.2. CSGEF expression controlled by androgen-responsive promoter of SGEF gene. SGEF may be regulator of Rho guanosine triphosphatases. CSGEF may function as regulator of Rho guanosine triphosphatase in prostate
This gene encodes a member of the Rho-guanine nucleotide exchange factor (Rho-GEF) family. These proteins regulate Rho GTPases by catalyzing the exchange of GDP for GTP. The encoded protein specifically activates RhoG and plays a role in the promotion of macropinocytosis. Underexpression of the encoded protein may be a predictive marker of chemoresistant disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Src homology 3 domain-containing guanine nucleotide exchange factor
, rho guanine nucleotide exchange factor 26
, SH3 domain-containing guanine exchange factor