You are viewing an incomplete version of our website. Please click to reload the website as full version.

rho-Related BTB Domain Containing 2 Proteins (RHOBTB2)

The protein encoded by RHOBTB2 is a small Rho GTPase and a candidate tumor suppressor. Additionally we are shipping rho-Related BTB Domain Containing 2 Antibodies (14) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RHOBTB2 23221 Q9BYZ6
RHOBTB2 246710 Q91V93
Rat RHOBTB2 RHOBTB2 306004  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top rho-Related BTB Domain Containing 2 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

RHOBTB2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for rho-Related BTB Domain Containing 2 (RHOBTB2) Interaction Partners

Human rho-Related BTB Domain Containing 2 (RHOBTB2) interaction partners

  1. Mutation in the promoter and exon 7 of DBC2 gene is not common in the Chinese population and may not contribute to the susceptibility for breast cancer in China

  2. data suggest a new paradigm for Hsp90 (show HSP90 Proteins)-modulated assembly of a Cul3 (show CUL3 Proteins)/DBC2 E3 ubiquitin ligase (show MUL1 Proteins) complex that may extend to other E3 ligase complexes.

  3. ). The results demonstrated that aberrant methylation of RhoBTB2 may be responsible for the suppression of RhoBTB2 mRNA expression in breast cancer, a significant event during the genesis of breast cancer that correlated with progesterone receptor (show PGR Proteins) status

  4. Thus loss of DBC2 expression is caused by abnormal methylation of DBC2 and might have a role in breast cancer development.

  5. Loss of DBC2 expression is an early and progressive event in the development of lung adenocarcinoma.

  6. Overexpression of RhoBTB2 in breast tumor cells significantly inhibited the proliferation and colony formation of tumor cells. In addition, RhoBTB2 also elevated the apoptotic ratio and caused typical changes of apoptotic morphology.

  7. RhoBTB2 is establishing itself as a tumor suppressor with increasing relevance towards malignancies.

  8. Ectopic expression of RhoBTB2 results in decreased phosphorylation of ezrin (show EZR Proteins) and Akt2 (show AKT2 Proteins) in both MDA-MB-231 and MDA-MB-435 cells.

  9. The expression of Fas (show FAS Proteins), CTLA-4 (show CTLA4 Proteins) and RhoBTB2 at the mRNA level is involved in genesis and progression of breast cancer.

  10. Frequent loss of RhoBTB2 expression is associated with sporadic breast cancer.

Mouse (Murine) rho-Related BTB Domain Containing 2 (RHOBTB2) interaction partners

  1. There is no connection between elevated expression of mDbc2/Rhobtb2 and a specific stage of mammary gland development, but this gene plays a critical role in the development of the nervous system.

rho-Related BTB Domain Containing 2 (RHOBTB2) Protein Profile

Protein Summary

The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RHOBTB2

  • tumor necrosis factor receptor superfamily, member 10b (TNFRSF10B)
  • Rho-related BTB domain containing 2 (RHOBTB2)
  • Rho-related BTB domain containing 2 (LOC100352605)
  • Rho-related BTB domain containing 2 (Rhobtb2)
  • Dbc2 protein
  • E130206H14Rik protein
  • mKIAA0717 protein
  • TVB protein

Protein level used designations for RHOBTB2

tumor necrosis factor receptor superfamily member 10B , rho-related BTB domain-containing protein 2 , Rho-related BTB domain containing 2 , subgroup E ALV receptor , rho-related BTB domain-containing protein 2-like , deleted in breast cancer 2 gene protein , p83 , deleted in breast cancer 2 gene protein homolog

GENE ID SPECIES
373904 Gallus gallus
419536 Gallus gallus
464050 Pan troglodytes
486120 Canis lupus familiaris
664712 Meleagris gallopavo
716607 Macaca mulatta
784567 Bos taurus
100030651 Monodelphis domestica
100057764 Equus caballus
100174455 Pongo abelii
100352605 Oryctolagus cuniculus
100414447 Callithrix jacchus
100602112 Nomascus leucogenys
23221 Homo sapiens
246710 Mus musculus
306004 Rattus norvegicus
Selected quality suppliers for rho-Related BTB Domain Containing 2 Proteins (RHOBTB2)
Did you look for something else?