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The protein encoded by RHOBTB1 belongs to the Rho family of the small GTPase superfamily. Additionally we are shipping RHOBTB1 Antibodies (46) and RHOBTB1 Kits (1) and many more products for this protein.
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we found that miR (show MLXIP Proteins)-31 acts as an oncogene (show RAB1A Proteins) in colon cancer and identified RhoBTB1 as a new target of miR (show MLXIP Proteins)-31 further study demonstrated that miR (show MLXIP Proteins)-31 contributed to the development of colon cancer at least partly by targeting RhoBTB1.
Frequent allelic loss and decreased expression of RHOBTB1 suggested that this gene has a role in tumorigenesis of a subset of HNSCC (Head-Neck Squamous Cell Carcinoma).
The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants.
rho-related BTB domain-containing protein 1
, Rho-related BTB domain containing 1
, rho-related BTB domain-containing protein 1-like