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anti-serine Dehydratase (SDS) Antibodies

SDS encodes one of three enzymes that are involved in metabolizing serine and glycine. Additionally we are shipping serine Dehydratase Kits (12) and serine Dehydratase Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SDS 10993 P20132
SDS 231691 Q8VBT2
SDS 25044 P09367
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Top anti-serine Dehydratase Antibodies at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, FACS, WB Flow Cytometry analysis of K562 cells using SDS Antibody (N-term) Cat.-No AP53827PU-N (Bottom histogram) compared to a negative control cell (Top histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis. Western blot analysis of SDS Antibody (N-term) Cat.-No AP53827PU-N in K562 cell line lysates (35 µg/lane). SDS (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of SDS Antibody (N-term) (ABIN652984) in K562 cell line lysates (35 µg/lane). SDS (arrow) was detected using the purified polyclonal antibody. SDS Antibody (N-term) (ABIN652984) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SDS Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HT1080 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-SDS mouse monoclonal antibody (ABIN2455307) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SDS (RC217814). Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-SDS mouse monoclonal antibody. (ABIN2455307) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells transfected with either RC217814 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-SDS antibody (ABIN2455348), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SDS (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SDS. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC217814 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-SDS antibody (ABIN2455350), and then analyzed by flow cytometry. Anti-SDS mouse monoclonal antibody (ABIN2455350) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SDS (RC217814). 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC217814 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-SDS antibody (ABIN2455352), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SDS (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SDS. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IHC, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SDS (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SDS. Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-SDS mouse monoclonal antibody. (ABIN2455349) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IF, WB Anti-SDS mouse monoclonal antibody (ABIN2455364) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SDS (RC217814). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SDS (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SDS. 100 μL Log in to see 2 to 3 Days
$423.50
Details

SDS Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
, ,
,
, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-serine Dehydratase Antibodies

  1. Human Polyclonal SDS Primary Antibody for EIA, FACS - ABIN954698 : Yamada, Komoto, Kasuya, Takata, Ogawa, Mori, Takusagawa: A catalytic mechanism that explains a low catalytic activity of serine dehydratase like-1 from human cancer cells: crystal structure and site-directed mutagenesis studies. in Biochimica et biophysica acta 2008 (PubMed)
    Show all 2 references for ABIN954698

  2. Human Polyclonal SDS Primary Antibody for WB - ABIN2773787 : Szaflik, Majsterek, Kowalski, Rusin, Sobczuk, Borucka, Szaflik, Blasiak: Association between sorbitol dehydrogenase gene polymorphisms and type 2 diabetic retinopathy. in Experimental eye research 2008 (PubMed)

More Antibodies against serine Dehydratase Interaction Partners

Human serine Dehydratase (SDS) interaction partners

  1. The low penetrance of SDHB (show SDHB Antibodies) mutations may obscure the hereditary nature of SDHB (show SDHB Antibodies)-linked disease and is important in the counseling of SDHB (show SDHB Antibodies)-linked patients.

  2. Succinate dehydrogenase (show SDHA Antibodies) deficiency is a rare leukoencephalopathy, for which improved recognition by magnetic resonance imaging (MRI (show C7ORF49 Antibodies)) in combination with advanced sequencing technologies allows noninvasive diagnostic confirmation.

  3. 15 YEARS OF PARAGANGLIOMA: Genetics and mechanism of pheochromocytoma-paraganglioma syndromes characterized by germline SDHB (show SDHB Antibodies) and SDHD (show SDHD Antibodies) mutations

  4. Study reveals new insights into the effects of SDHB (show SDHB Antibodies) mutations and the power of structural modelling in predicting biological consequences.

  5. for the first time, we show a high correlation between urinary bladder paragangliomas and SDHB (show SDHB Antibodies) mutations

  6. Findings provide a conceptual framework for understanding how particular mutations disproportionately cause the loss of SDH (show SARDH Antibodies) activity, resulting in accumulation of succinate and metabolic remodeling in SDHB (show SDHB Antibodies) cancer syndromes.

  7. Germline mutation in the SDHB (show SDHB Antibodies) gene is the only reliable predictor of malignant Paragangliomas.

  8. Report direct correlation between the presence of an SDHB (show SDHB Antibodies) mutation, whether germline or somatic, and negative SDHB (show SDHB Antibodies) immunohistochemical staining in bladder paragangliomas.

  9. This study strengthens the etiological association of SDH (show SARDH Antibodies) genes with pituitary neoplasia, renal tumorigenesis, and gastric gastrointestinal stromal tumors. Also, pancreatic neuroendocrine tumor falls within the SDH (show SARDH Antibodies)-related tumor spectrum.

  10. SDHB (show SDHB Antibodies) immunohistochemistry alone may be misleading in excluding tumors other than gastrointestinal stromal tumors

Mouse (Murine) serine Dehydratase (SDS) interaction partners

  1. Deficiency of the ribosome biogenesis gene Sbds (show SBDS Antibodies) in hematopoietic stem and progenitor cells causes neutropenia in mice by attenuating lineage progression in myelocytes

  2. Sbds (show SBDS Antibodies) genotypes correlated with phenotypes in a mouse model of Shwachman-Diamond syndrome. Defects developed specifically in the pancreata of mice, reducing growth of mice and production of digestive enzymes.

  3. Sbds (show SBDS Antibodies) is required for osteoclastogenesis by regulating monocyte migration via Rac2 (show RAC2 Antibodies) and osteoclast differentiation signaling downstream of RANK.

  4. Sbds (show SBDS Antibodies) is an essential gene for early mammalian development, with an expression pattern consistent with a critical role in cell proliferation.

  5. loss of Sbds (show SBDS Antibodies) is sufficient to induce abnormalities in hematopoiesis

  6. The majority of Shwachman-Diamond syndrome cases are results of mutations in SBDS (show SBDS Antibodies) gene on chromosone 7q11.

serine Dehydratase (SDS) Antigen Profile

Protein Summary

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

Gene names and symbols associated with SDS

  • serine dehydratase (SDS) antibody
  • serine dehydratase (sds) antibody
  • serine dehydratase (Sds) antibody
  • Shwachman-Bodian-Diamond syndrome homolog (human) (Sbds) antibody
  • succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (SDHB) antibody
  • 4432411H13Rik antibody
  • 4733401P19Rik antibody
  • AI836084 antibody
  • CGI-97 antibody
  • CWS2 antibody
  • IP antibody
  • PGL4 antibody
  • RATSDHE1 antibody
  • Sdh antibody
  • SDH1 antibody
  • SDH2 antibody
  • Sdhe1 antibody
  • SDHIP antibody
  • SDS antibody
  • TDH antibody

Protein level used designations for SDS

serine dehydratase , L-serine dehydratase/L-threonine deaminase , L-serine ammonia-lyase , L-serine deaminase , L-serine dehydratase , L-threonine dehydratase , TDH , SDH , protein 22A3 , ribosome maturation protein SBDS , shwachman-Bodian-Diamond syndrome protein homolog , iron-sulfur subunit of complex II , succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

GENE ID SPECIES
452274 Pan troglodytes
486281 Canis lupus familiaris
713285 Macaca mulatta
100036931 Xenopus laevis
100101671 Xenopus (Silurana) tropicalis
100155595 Sus scrofa
10993 Homo sapiens
231691 Mus musculus
25044 Rattus norvegicus
514346 Bos taurus
66711 Mus musculus
6390 Homo sapiens
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