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The protein encoded by SPINK6 is a Kazal-type serine protease inhibitor that acts on kallikrein-related peptidases in the skin. Additionally we are shipping SPINK6 Antibodies (13) and SPINK6 Kits (3) and many more products for this protein.
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our results identified a novel EGFR (show EGFR Proteins)-activating mechanism in which SPINK6 has a critical role in promoting nasopharyngeal carcinoma metastasis
a significant fraction of SPINK6-sensitive proteases in healthy saliva (show RAG1AP1 Proteins) and confirmed the ability of gingipains to inactivate SPINK6 under ex vivo conditions
Our study indicates that Spink6 is a potent inhibitor of kallikrein (show KLK4 Proteins) related peptidases and involved in skin barrier function.
Cross-linked SPINK6 might protect specific substrates such as fibronectin (show FN1 Proteins) from kallikrein (show KLK4 Proteins)-related peptidases cleavage and contribute to the regulation of proteases in the epidermis.
Serine protease (show F2 Proteins) of Kazal-type (SPINK6) expressed in normal human skin is a potent natural inhibitor of Kallikrein (show KLK4 Proteins)-related peptidases, KLK12 (show KLK12 Proteins) and KLK13 (show KLK13 Proteins).
Data suggest that SPINK6 plays a role in modulating the activity of kallikreins in human skin.
Our study indicates that Spink6 is a potent inhibitor of kallikrein (show KLK1 Proteins) related peptidases and involved in skin barrier function.
The protein encoded by this gene is a Kazal-type serine protease inhibitor that acts on kallikrein-related peptidases in the skin. Two transcript variants the same protein have been found for this gene.
, kallikrein inhibitor
, protease inhibitor H
, serine protease inhibitor Kazal-type 6
, Kazal type serine protease inhibitor 1