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serine threonine Kinase 39 Proteins (STK39)

STK39 encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. Additionally we are shipping STK39 Antibodies (182) and STK39 Kits (16) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
STK39 27347 Q9UEW8
STK39 54348 O88506
STK39 53416 Q9Z1W9
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Top STK39 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag   10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,582.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

STK39 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Mouse (Murine)

Top referenced STK39 Proteins

  1. Human STK39 Protein expressed in Wheat germ - ABIN1321704 : Mao, Ladd, Gad, Rastetter, Johnson, Marzbani, Childs, Lu, Dang, Broussard, Stanton, Hanash, Disis: Mining the pre-diagnostic antibody repertoire of TgMMTV-neu mice to identify autoantibodies useful for the early detection of human breast cancer. in Journal of translational medicine 2014 (PubMed)

More Proteins for serine threonine Kinase 39 (STK39) Interaction Partners

Human serine threonine Kinase 39 (STK39) interaction partners

  1. SPAK and OSR1 (show OXSR1 Proteins) are both stimulators of Kir2.1 (show KCNJ2 Proteins) activity.

  2. SPAK and OSR1 (show OXSR1 Proteins) are powerful stimulators of the intestinal Na+-coupled phosphate co-transporter NaPi-IIb (show SLC34A2 Proteins)

  3. Single nucleotide polymorphisms STK39 and WNK1 (show WNK1 Proteins) were associated with hypertension and BP in our multicenter Belgian case-control study

  4. STK39 mRNA and protein express abnormally in primary hypertension patients with genetic variation, which is related to the blood pressure.

  5. SPAK protein has both the potential to up-regulate KCNQ1 (show KCNQ1 Proteins)/E1 protein abundance in the cell membrane, an effect possibly participating in the regulation of cell volume, excitability, epithelial transport and metabolism.

  6. SPAK and OSR1 (show OXSR1 Proteins) are powerful negative regulators of the excitatory glutamate (show GRIN1 Proteins) transporters EAAT1 (show SLC1A3 Proteins) and EAAT2 (show SLC1A2 Proteins).

  7. SPAK and OSR1 (show OXSR1 Proteins) are negative regulators of EAAT3 (show SLC1A1 Proteins) activity

  8. These observations establish that the CCT (show FLVCR2 Proteins) domain plays a crucial role in controlling SPAK activity and BP.

  9. Findings indicate that the serine threonine kinase 39 (STK39) mRNA expression is increased in rs3754777 knockin cell lines.

  10. These findings suggested that the STK39 rs1955337 TT genotype is a risk factor for Han-Chinese patients with PD in Taiwan

Mouse (Murine) serine threonine Kinase 39 (STK39) interaction partners

  1. We conclude that TRPV2 (show TRPV2 Proteins) is involved in osmosensation in skeletal muscle fibres, acting in concert with P-SPAK-activated NKCC1 (show SLC12A2 Proteins)

  2. SPAK has the potential to up-regulate ENaC (show SCNN1A Proteins)

  3. These observations establish that the CCT (show FLVCR2 Proteins) domain plays a crucial role in controlling SPAK activity and BP.

  4. The data of this study supported the gene-environment hypothesis and demonstrated the potential value of SPAK manipulation in future schizophrenia studies.

  5. The structure of partially active SPAK T243D is consistent with a multistage activation process in which phosphorylation induces a SPAK conformation that requires further remodeling to build the active structure.

  6. ROMK1 (show KCNJ1 Proteins) protein abundance and activity are down-regulated by SPAK and OSR1 (show OSR1 Proteins)

  7. In conclusion, SPAK is a powerful negative regulator of SGLT1 (show SLC5A1 Proteins) protein abundance in the cell membrane and thus of electrogenic glucose transport.

  8. SPAK is an important mediator of the increased NCC (show SLC12A3 Proteins) activation by phosphorylation that occurs in the distal convoluted tubule in response to a low-K(+) diet, but other low-potassium-activated kinases are likely to be involved.

  9. combined net effect of SPAK isoforms on sodium reabsorption in thick ascending limb is stimulatory

  10. study identifies a separation of functions for the WNK1 (show WNK1 Proteins)-activated protein kinases OSR1 (show OSR1 Proteins) and SPAK in mediating proliferation, invasion, and gene expression in endothelial cells

STK39 Protein Profile

Protein Summary

This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress.

Gene names and symbols associated with STK39

  • serine threonine kinase 39 (STE20/SPS1 homolog) (stk39)
  • serine threonine kinase 39 (STE20/SPS1 homolog, yeast) (STK39)
  • serine threonine kinase 39 (STK39)
  • serine threonine kinase 39 (stk39)
  • serine threonine kinase 39 (Stk39)
  • serine/threonine kinase 39 (Stk39)
  • serine/threonine kinase 39 (LOC100338897)
  • AW227544 protein
  • AW556857 protein
  • DCHT protein
  • MGC69537 protein
  • PASK protein
  • RF005 protein
  • Rnl5 protein
  • Spak protein

Protein level used designations for STK39

serine threonine kinase 39 (STE20/SPS1 homolog) , serine threonine kinase 39 (STE20/SPS1 homolog, yeast) , serine threonine kinase 39 , serine/threonine kinase 39 , STE20/SPS1 homolog , STE20/SPS1-related proline-alanine-rich protein kinase , Ste20-like protein kinase , proline-alanine-rich STE20-related kinase , serine/threonine-protein kinase 39 , small intestine SPAK-like kinase , ste-20-related kinase , PS/TK , PSTK1 , Ste-20 related kinase , pancreatic serine/threonine-protein kinase , kidney-specific SPAK , serine/threonine kinase 39, STE20/SPS1 homolog

GENE ID SPECIES
407902 Xenopus (Silurana) tropicalis
459711 Pan troglodytes
704855 Macaca mulatta
100016925 Monodelphis domestica
100062610 Equus caballus
100598685 Nomascus leucogenys
446749 Xenopus laevis
27347 Homo sapiens
522103 Bos taurus
54348 Rattus norvegicus
424173 Gallus gallus
478779 Canis lupus familiaris
100517614 Sus scrofa
100714990 Cavia porcellus
53416 Mus musculus
100338897 Oryctolagus cuniculus
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