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anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) Antibodies

SRSF1 encodes a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. Additionally we are shipping SRSF1 Kits (18) and SRSF1 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SRSF1 6426 Q07955
SRSF1 110809 Q6PDM2
SRSF1 689890  
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Top anti-SRSF1 Antibodies at antibodies-online.com

Showing 10 out of 61 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-SFRS1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate WB Suggested Anti-SFRS1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: HepG2 cell lysate  There is BioGPS gene expression data showing that SRSF1 is expressed in HepG2 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of SFRS1 Antibody (C-term) (ABIN390841) in HL-60 cell line lysates (35 µg/lane). SFRS1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human colon carcinoma reacted with SFRS1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of SFRS1 Antibody (N-term) (ABIN652256) in A2058, WiDr cell line lysates (35 µg/lane). SFRS1 (arrow) was detected using the purified polyclonal antibody. SFRS1 Antibody (N-term) (ABIN652256) IHC analysis in formalin fixed and paraffin embedded testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-SFRS1 Antibody Titration: 5.0ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate WB Suggested Anti-SFRS1  Antibody Titration: 5.0 µg/mL ELISA Titer: 1:.12500  Positive Control: HepG2 cell lysate  There is BioGPS gene expression data showing that SRSF1 is expressed in HepG2 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-Fixed, Paraffin-Embedded Human colon carcinoma reacted with SFRS1 Antibody (C-term), which was Peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis of SFRS1 Antibody (C-term) in HL-60 cell line lysates (35ug/lane). SFRS1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- SF2 Picoband antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue Anti- SF2 Picoband antibody, IHC(P) IHC(P): Mouse Brain Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated IF, IHC (p), IP, WB Human Kidney (formalin-fixed, paraffin-embedded) stained with SFRS1 antibody ABIN337068 at 5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$595.83
Details
Human Mouse Un-conjugated IF, IHC (p), WB Human Thymus (formalin-fixed, paraffin-embedded) stained with SFRS1 antibody ABIN461956 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. Human Breast (formalin-fixed, paraffin-embedded) stained with SFRS1 antibody ABIN461956 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$595.83
Details

SRSF1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine)


Rat (Rattus)


Top referenced anti-SRSF1 Antibodies

  1. Chicken Polyclonal SRSF1 Primary Antibody for WB - ABIN2779013 : Velazquez-Dones, Hagopian, Ma, Zhong, Zhou, Ghosh, Fu, Adams: Mass spectrometric and kinetic analysis of ASF/SF2 phosphorylation by SRPK1 and Clk/Sty. in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 references for ABIN2779013

  2. Human Polyclonal SRSF1 Primary Antibody for EIA, IHC (p) - ABIN453373 : Sugiyama, Masuda, Shinoda, Nakamura, Tomita, Ishihama: Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications. in Molecular & cellular proteomics : MCP 2007 (PubMed)

More Antibodies against SRSF1 Interaction Partners

Fruit Fly (Drosophila melanogaster) serine/arginine-Rich Splicing Factor 1 (SRSF1) interaction partners

  1. ASF1 cellular levels are tightly controlled by distinct pathways and provide a molecular mechanism for post-translational regulation of dASF1 and hASF1a (show ASF1A Antibodies) by TLK (show TLK2 Antibodies) kinases.

  2. dASF1 has a direct role in modifying chromatin structure during DNA replication and this function of dASF1 is important for the processivity of the replication machinery.

  3. Asf1 is directed via interactions with sequence-specific complexes to mediate silencing of specific target genes.

  4. Histone chaperones ASF1 and NAP1 (show NAP1L1 Antibodies) differentially modulate removal of active histone marks by LID-RPD3 (show HDAC1 Antibodies) complexes during NOTCH (show NOTCH1 Antibodies) silencing.

Human serine/arginine-Rich Splicing Factor 1 (SRSF1) interaction partners

  1. results strongly support SRSF1 as a prognostic biomarker in SCLC and provide a rationale for personalized therapy in SCLC

  2. NSrp70 (show NSRP1 Antibodies) acts as a new molecular counterpart for alternative splicing of target RNA, counteracting SRSF1 and SRSF2 (show SRSF2 Antibodies) splicing activity.

  3. we have identified for the first time a potential mechanism that involves the essential splicing factor (show SLU7 Antibodies) ASF/SF2 through which morphine regulates splicing specificity of the MOR (show OPRM1 Antibodies) encoding gene, OPRM1 (show OPRM1 Antibodies).

  4. Global splicing analysis with RNA-seq revealed that exons carrying the hnRNP H (show HNRNPH1 Antibodies)-binding GGGGG motif are predisposed to be skipped compared to those carrying the SRSF1-binding GGAGG motif in both human and mouse brains.

  5. We present experimental evidence that splicing factor (show SLU7 Antibodies) SRSF1, SRSF2 (show SRSF2 Antibodies), U2AF35 (show U2AF1 Antibodies), U2AF65 (show U2AF59 Antibodies) and KHSRP (show KHSRP Antibodies) expression levels in gastrointestinal tract (colon, gastric and pancreatic) tumors differ compare to healthy tissues and in cell lines

  6. These findings have revealed a molecular interplay between cellular SRSF1 and viral T-antigen in controlling JC virus gene expression.

  7. These include alternative splicing of SRSF1 itself.

  8. SF2 contributes to the elevated levels of ERK (show EPHB2 Antibodies) activation in hepatocellular carcinoma cells through modulating key component(s) downstream of growth factor receptors and upstream of ERK (show EPHB2 Antibodies).

  9. These results suggest that MALAT1 may function as a promoter of gastric cancer cell proliferation partly by regulating SF2/ASF.

  10. SRSF1 regulates CD3zeta (show CD247 Antibodies) expression in human T cells and may contribute to the T cell defect in systemic lupus erythematosus.

Mouse (Murine) serine/arginine-Rich Splicing Factor 1 (SRSF1) interaction partners

  1. The expression levels of three splicing factors, ESRP1 (show ESRP1 Antibodies), PTB (show PTBP1 Antibodies) and SF2/ASF, are significantly altered during cardiac hypertrophy in mice.

  2. RRP1B suppresses metastatic progression by altering the transcriptome through its interaction with splicing regulators such as SRSF1

  3. Deletion of RRM1 (show RRM1 Antibodies) eliminated the splicing activity of SRSF1 and thus cellular transformation.

  4. Specific effects on regulated splicing by SR proteins SRSF1 and SRSF2 (show SRSF2 Antibodies) depends on a complex set of relationships with multiple other SR proteins in mammalian genomes.

  5. Treatment with IL-17 (show IL17A Antibodies) prolongs the half-life of chemokine (show CCL1 Antibodies) CXCL1 (show CXCL1 Antibodies) mRNA via the adaptor TRAF5 (show TRAF5 Antibodies) and the splicing-regulatory factor SF2 (ASF).

  6. analysis of the miRNA-mediated interaction between leukemia/lymphoma-related factor (LRF (show ZBTB7A Antibodies)) and alternative splicing factor/splicing factor (show SLU7 Antibodies) 2 (ASF/SF2) affects cell senescence and apoptosis

  7. Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 (show SMN1 Antibodies) causes spinal muscular atrophy in the absence of SMN1 (show SMN1 Antibodies)

  8. Both hnRNP A1 (show HNRNPA1 Antibodies) and alternative splicing factor/splicing factor (show SLU7 Antibodies) 2 contents rose in adenomas and during injury-induced hyperplasia compared to control lungs

  9. These results highlight the requirement of Sfrs1-mediated alternative splicing for the survival of retinal neurons, with sensitivity defined by the window of time in which the neuron was generated.

SRSF1 Antigen Profile

Protein Summary

This gene encodes a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. Multiple transcript variants encoding different isoforms have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 13.

Gene names and symbols associated with SRSF1

  • anti-silencing factor 1 (asf1) antibody
  • serine/arginine-rich splicing factor 1 (srsf1) antibody
  • serine/arginine-rich splicing factor 1 (SRSF1) antibody
  • serine/arginine-rich splicing factor 1 (Srsf1) antibody
  • serine/arginine-rich splicing factor 1b (srsf1b) antibody
  • 1110054N12Rik antibody
  • 5730507C05Rik antibody
  • 6330415C05Rik antibody
  • AI482334 antibody
  • Asf antibody
  • Asf1 antibody
  • AW491331 antibody
  • CG9383 antibody
  • dASF/SF2 antibody
  • dAsf1 antibody
  • DKFZp469K2419 antibody
  • Dmel\\CG9383 antibody
  • l(3)76BDq antibody
  • Sf2 antibody
  • SF2p33 antibody
  • Sfrs1 antibody
  • sfrs1b antibody
  • SRp30a antibody
  • wu:fb80g05 antibody
  • zgc:65898 antibody
  • zgc:76897 antibody
  • zgc:111894 antibody

Protein level used designations for SRSF1

CG9383-PA , CG9383-PB , anti- silencing function 1 , anti-silencing factor , asf1-PA , asf1-PB , splicing factor, arginine/serine-rich 1 (splicing factor 2, alternate splicing factor) , ASF-1 , SR splicing factor 1 , alternative-splicing factor 1 , pre-mRNA-splicing factor SF2, P33 subunit , splicing factor 2 , splicing factor, arginine/serine-rich 1 , splicing factor arginine/serine-rich 1 , splicing factor, arginine/serine-rich 1B , ASF/SF2 , pre-mRNA-splicing factor SRp30a , splicing factor, arginine/serine-rich 1 (ASF/SF2) , serine/arginine-rich splicing factor 1B , splicing factor, arginine/serine-rich 1b

GENE ID SPECIES
40141 Drosophila melanogaster
399226 Xenopus laevis
772264 Gallus gallus
6426 Homo sapiens
609693 Canis lupus familiaris
654327 Sus scrofa
615796 Bos taurus
110809 Mus musculus
689890 Rattus norvegicus
100173318 Pongo abelii
393565 Danio rerio
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