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SRSF10 product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Additionally we are shipping SRSF10 Proteins (4) and many more products for this protein.
Showing 10 out of 69 products:
Chicken Polyclonal SRSF10 Primary Antibody for WB - ABIN2779003
Shi, Manley: A complex signaling pathway regulates SRp38 phosphorylation and pre-mRNA splicing in response to heat shock. in Molecular cell 2007
Chicken Polyclonal SRSF10 Primary Antibody for IHC, WB - ABIN2776611
Shin, Kleiman, Manley: Multiple properties of the splicing repressor SRp38 distinguish it from typical SR proteins. in Molecular and cellular biology 2005
Results show that YTHDC1 (show YTHDC1 Antibodies) promotes exon inclusion in targeted mRNAs through recruiting pre-mRNA splicing factor (show SNRPB Antibodies) SRSF3 (show SRSF3 Antibodies) while blocking SRSF10 mRNA binding.
SRSF10 is a key regulator of BCLAF1 (show BCLAF1 Antibodies) pre-mRNA splicing and the maintenance of oncogenic features in human colon cancer cells
In colorectal cancer, NSSR1 was highly expressed in the nucleus of tumor cells.
Splicing thermotolerance is acquired through maintenance of SRSF10 phosphorylation and that this is mediated at least in part by Hsp27 (show HSPB1 Antibodies).
Data show that SFRS13A expression was significantly associated with LDLR (show LDLR Antibodies) splicing efficiency in vivo.
found to be dephosphorylated specifically in mitotic cells; show that dephosphorylated SRp38 is required for the observed splicing repression
SRp38 plays a crucial role in cell survival under stress conditions by inhibiting the splicing machinery
SRp38 contains two arginine- and serine-rich domains (RS), one of which has a unique, second-step repression activity, while both function together as a splicing repression domain.
SRSF10 represses inclusion of PGC1alpha exon 7a.
The results of this study suggested for the first time that NSSR1 may provide a novel mechanism for reducing neuronal injury after ischemia, probably through regulation on alternative splicing of NCAM-L1 (show L1CAM Antibodies) and CREB (show CREB1 Antibodies) in astrocytes.
We further show that an SRSRSK sequence in the RS3 (show EDAR Antibodies) domain may play an important role in the function of NSSR1 in pre-mRNA splicing.
These results identify SRSF10 as an essential regulator for adipocyte differentiation.
the potential roles of NSSR1 in sperm maturation and fertilization
NSSR1 mRNA was expressed in mouse cerebrum, cerebellum, heart, liver, intestine, kidney and lung tissue, but NSSR1 protein was only expressed in neural tissues.
The NSSR1 promotes neuronal differentiation and the splicing of NCAML1 (show L1CAM Antibodies) exon2 and TrkC (show NTRK3 Antibodies)-K1.
NSSR1 and NSSR2 function as splicing modulators via binding to pre-mRNAs.
The findings for the first time provide the evidence indicating the potential importance of NSSR1 in testes development, spermatogenesis and cryptorchidism.
This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. This gene has multiple pseudogenes. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist.
serine/arginine-rich splicing factor 10
, FUS interacting protein (serine-arginine rich) 1
, FUS interacting protein (serine/arginine-rich) 1
, splicing factor, arginine/serine-rich 13A
, 40 kDa SR-repressor protein
, FUS-interacting protein (serine-arginine rich) 2
, FUS-interacting serine-arginine-rich protein 1
, SR splicing factor 10
, TLS-associated SR protein
, TLS-associated protein TASR
, TLS-associated protein with SR repeats
, TLS-associated protein with Ser-Arg repeats
, TLS-associated serine-arginine protein 1
, TLS-associated serine-arginine protein 2
, neural-salient SR protein
, serine-arginine repressor protein (40 kDa)
, splicing factor SRp38
, splicing factor, arginine/serine-rich 13
, Fus-associated protein with serine-arginine repeats
, TLS-associated serine-arginine protein
, neural-salient serine/arginine-rich protein
, neural-specific SR protein
, serine/arginine-rich splicing factor 13A