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anti-serine/arginine-Rich Splicing Factor 2 (SRSF2) Antibodies

The protein encoded by SRSF2 is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Additionally we are shipping SRSF2 Kits (10) and SRSF2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SRSF2 6427 Q01130
SRSF2 20382 Q62093
SRSF2 494445 Q6PDU1
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Top anti-SRSF2 Antibodies at antibodies-online.com

Showing 10 out of 35 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of SFRS2 Antibody (Center) (ABIN650729) in mouse stomach tissue lysates (35 µg/lane). SFRS2 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-SFRS2 Antibody (N-term) (ABIN389301) in K562 cell line lysates (35 µg/lane).SFRS2(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with SFRS2 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of SFRS2 Antibody (Center) in mouse stomach tissue lysates (35ug/lane). SFRS2 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IF, IP, WB Western blot analysis of SC35. Lysates from MG-63 human osteosarcoma cells were probed with anti-SC35 (clone alphaSC35, ABIN967516). SC35 is detected as a band of ~35 kDa. 0.1 mg Log in to see 5 to 6 Days
$236.41
Details
Human Rabbit Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 6 Days
$302.50
Details
Amphibian Mouse Un-conjugated ELISA, EM, ICC, IF, IP, WB   0.1 mL Log in to see 5 to 7 Days
$366.19
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SFRS2 AntibodyTitration: 1.0 µg/mL  Positive Control: Hela Whole Cell  SRSF2 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA   50 μg Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated IHC (p), WB Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details

SRSF2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
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Mouse (Murine)


Rat (Rattus)
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Top referenced anti-SRSF2 Antibodies

  1. Human Polyclonal SRSF2 Primary Antibody for EIA, IHC (p) - ABIN357967 : Merdzhanova, Edmond, De Seranno, Van den Broeck, Corcos, Brambilla, Brambilla, Gazzeri, Eymin: E2F1 controls alternative splicing pattern of genes involved in apoptosis through upregulation of the splicing factor SC35. in Cell death and differentiation 2008 (PubMed)
    Show all 4 references for ABIN357967

  2. Human Polyclonal SRSF2 Primary Antibody for EIA, WB - ABIN453825 : Solis, Peng, Crawford, Phillips, Patton: Growth hormone deficiency and splicing fidelity: two serine/arginine-rich proteins, ASF/SF2 and SC35, act antagonistically. in The Journal of biological chemistry 2008 (PubMed)
    Show all 4 references for ABIN453825

  3. Human Monoclonal SRSF2 Primary Antibody for IF, IP - ABIN967516 : Fu: Specific commitment of different pre-mRNAs to splicing by single SR proteins. in Nature 1993 (PubMed)
    Show all 3 references for ABIN967516

  4. Human Polyclonal SRSF2 Primary Antibody for IHC (p), WB - ABIN389301 : Sureau, Soret, Vellard, Crochet, Perbal: The PR264/c-myb connection: expression of a splicing factor modulated by a nuclear protooncogene. in Proceedings of the National Academy of Sciences of the United States of America 1993 (PubMed)
    Show all 2 references for ABIN389301

More Antibodies against SRSF2 Interaction Partners

Human serine/arginine-Rich Splicing Factor 2 (SRSF2) interaction partners

  1. NSrp70 (show NSRP1 Antibodies) acts as a new molecular counterpart for alternative splicing of target RNA, counteracting SRSF1 (show SRSF1 Antibodies) and SRSF2 splicing activity.

  2. We present experimental evidence that splicing factor (show SLU7 Antibodies) SRSF1 (show SRSF1 Antibodies), SRSF2, U2AF35 (show U2AF1 Antibodies), U2AF65 (show U2AF59 Antibodies) and KHSRP (show KHSRP Antibodies) expression levels in gastrointestinal tract (colon, gastric and pancreatic) tumors differ compare to healthy tissues and in cell lines.

  3. Data show that tet methylcytosine dioxygenase 2 TET2 (show TET2 Antibodies), isocitrate dehydrogenases 1/2 IDH1 (show IDH1 Antibodies)/IDH2 (show IDH2 Antibodies), serine/arginine-rich splicing factor 2 SRSF2, splicing factor 3b subunit 1 SF3B1 (show SF3B1 Antibodies), and ras proteins (KRAS/NRAS) are not conserved in dog mast Cell tumors.

  4. Depletion of two of the most potent inhibitors of SMP2 (show LPIN3 Antibodies) exon 7 inclusion, SRSF2 or SRSF3 (show SRSF3 Antibodies), in cell lines derived from SMA (show SMN1 Antibodies) patients, increased SMN2 (show SMN1 Antibodies) exon 7 inclusion and SMN (show STMN1 Antibodies) protein level.

  5. HIV-1-Tat (show TAT Antibodies) Protein Inhibits SC35-mediated Tau Exon 10 Inclusion through Up-regulation of DYRK1A (show DYRK1A Antibodies) Kinase.

  6. Our results show that diverse microenvironment cues affect different attributes of the SC-35 organizational metrics and lead to distinct emergent organizational patterns.

  7. findings shed light on the mechanism of the disease-associated SRSF2 mutation in splicing regulation and also reveal a group of misspliced mRNA isoforms for potential therapeutic targeting

  8. The authors propose that splicing at 3'ss A3 is dependent on binding of the enhancing SR proteins SRSF2 and SRSF6 (show SRSF6 Antibodies) to the HIV-1 tat (show TAT Antibodies) ESE and ESE2 (show ELF5 Antibodies) sequence.

  9. clinical relevance of SRSF2 mutations in Chinese myelodysplastic syndrome

  10. SRSF2 mutations are frequent in chronic myelomonocytic leukemia patients, but show a relatively lower incidence in Chinese patients.

Mouse (Murine) serine/arginine-Rich Splicing Factor 2 (SRSF2) interaction partners

  1. HIV-1-Tat (show TAT Antibodies) Protein Inhibits SC35-mediated Tau Exon 10 Inclusion through Up-regulation of DYRK1A (show DYRK1A Antibodies) Kinase.

  2. The findings suggest that intact SRSF2 is essential for the functional integrity of the hematopoietic system and that its mutations likely contribute to development of myelodysplastic syndromes.

  3. SRSF2 mutations alter SRSF2's normal sequence-specific RNA binding activity, thereby altering the recognition of specific exonic splicing enhancer motifs to drive recurrent mis (show AMH Antibodies)-splicing of key hematopoietic regulators

  4. Study reports that SRSF2 (also known as SC35, an SR-splicing factor (show SLU7 Antibodies)) is part of the 7SK complex assembled at gene promoters and plays a direct role in transcription pause release.

  5. Specific effects on regulated splicing by SR proteins SRSF1 (show SRSF1 Antibodies) and SRSF2 depends on a complex set of relationships with multiple other SR proteins in mammalian genomes.

  6. Deficiency of the splicing factor (show SLU7 Antibodies) Sfrs10 results in early embryonic lethality in mice and has no impact on full-length SMN/Smn (show STMN1 Antibodies) splicing.

  7. Oct-4 distribution was examined relative to that of the unphosphorylated form of RNA polymerase II (Pol II) and splicing factor (SC 35) in the intranuclear entities such as perichromatin fibrils.

  8. intranuclear distribution of SC35 is dependent on GSK-3 (show GSK3b Antibodies)

  9. These findings reveal the involvement of SC35 in specific pathways in regulating cell proliferation and genomic stability during mammalian organogenesis and suggest its potential function in tumorigenesis.

  10. splicing factor SC35 has an active role in transcriptional elongation

SRSF2 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11.

Gene names and symbols associated with SRSF2

  • serine/arginine-rich splicing factor 2 (SRSF2) antibody
  • serine/arginine-rich splicing factor 2 (Srsf2) antibody
  • serine/arginine-rich splicing factor 2 (srsf2) antibody
  • D11Wsu175e antibody
  • MRF-1 antibody
  • pr264 antibody
  • sc-35 antibody
  • sc35 antibody
  • sfrs2 antibody
  • sfrs2a antibody
  • Sfrs10 antibody
  • srp30b antibody

Protein level used designations for SRSF2

SR splicing factor 2 , splicing component, 35 kDa , splicing factor SC35 , splicing factor, arginine/serine-rich 2 , myelin regulatory factor 1 , putative myelin regulatory factor 1 , splicing factor Sc35 , splicing factor, arginine/serine-rich 2 (SC-35) , SC-35 , PR 264 protein , arginine/serine-rich2 splicing factor

GENE ID SPECIES
6427 Homo sapiens
20382 Mus musculus
494445 Rattus norvegicus
508312 Bos taurus
396195 Gallus gallus
768117 Sus scrofa
380435 Xenopus laevis
Selected quality suppliers for anti-SRSF2 (SRSF2) Antibodies
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