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serine/arginine-Rich Splicing Factor 5 Proteins (SRSF5)

The protein encoded by SRSF5 is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Additionally we are shipping SRSF5 Antibodies (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SRSF5 6430 Q13243
SRSF5 20384 O35326
Rat SRSF5 SRSF5 29667 Q09167
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Top SRSF5 Proteins at

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days

SRSF5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine)

More Proteins for serine/arginine-Rich Splicing Factor 5 (SRSF5) Interaction Partners

Human serine/arginine-Rich Splicing Factor 5 (SRSF5) interaction partners

  1. Suggest that SRp40 might be associated with GRalpha transcripts in systemic lupus erythematosus patients.

  2. We show that changes in alternative splicing of hnRNP A/B (show HNRNPAB Proteins), affected by up regulation of SRSF5 (SRp40) or by treatment with C6-ceramide, occur within supraspliceosomes.

  3. Relative levels of SRp20 (show SRSF3 Proteins), SRp30c (show SFRS9 Proteins), and SRp40 in TM cells control differential expression of the two alternatively spliced isoforms of the GR and thereby regulate GC responsiveness.

  4. Here, the authors report that specific SR proteins, particularly SRp40 and SRp55 (show SRSF6 Proteins), promote human immunodeficiency virus type 1 (HIV-1) Gag translation from unspliced (intron-containing) viral RNA.

  5. SRp40 antagonizes ASF/SF2 (show SRSF1 Proteins) and SRp55 (show SRSF6 Proteins) by competing for binding to certain sites in exon 5, thereby promoting TF exon 5 exclusion, an event unique to asTF biosynthesis.

  6. SR proteins 9G8 (show SFRS7 Proteins), SC35 (show SRSF2 Proteins), ASF/SF2 (show SRSF1 Proteins), and SRp40 have effects on the utilization of the A1 to A5 splicing sites of HIV-1 RNA

  7. activates the ESE (exon splicing enhancer) which regulates HIV-1 rev, env (show ERVW-1 Proteins), vpu, and nef gene expression

  8. SRp40 regulates the switch in splicing from production of CREMtau(2)alpha to CREMalpha

  9. SC35 (show SRSF2 Proteins), SRp40, and heterogeneous nuclear ribonucleoprotein A1 (show HNRNPA1 Proteins) interact competitively at the HIV-1 Tat (show TAT Proteins) exon 2 splicing site

Mouse (Murine) serine/arginine-Rich Splicing Factor 5 (SRSF5) interaction partners

  1. overexpression of SRSF5 enhances a specific endogenous pre-mRNA splicing event in proliferating cells, but not in differentiating cells, due to proteasome-mediated targeting of both endogenous and transfection-derived SRSF5.

  2. Data show that Akt (show AKT1 Proteins)-mediated signaling promotes protein kinase (show CDK7 Proteins) CbetaII alternative splicing via phosphorylation of SRp40.

  3. the effects of TGF-beta1 (show TGFB1 Proteins) on FN splicing during chondrogenesis may be largely dependent on its effect on SRp40 isoform expression

SRSF5 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with SRSF5

  • serine/arginine-rich splicing factor 5 (SRSF5)
  • serine/arginine-rich splicing factor 5 (Srsf5)
  • HRS protein
  • Sfrs5 protein
  • SRp40 protein

Protein level used designations for SRSF5

SR splicing factor 5 , delayed-early protein HRS , pre-mRNA-splicing factor SRP40 , splicing factor, arginine/serine-rich 5 , splicing factor, arginine/serine-rich 5 (SRp40, HRS) , insulin-induced growth response protein CL-4 , splicing factor arginine/serine-rich 5 (SRp40 HRS)

6430 Homo sapiens
20384 Mus musculus
29667 Rattus norvegicus
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