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serine/threonine Kinase 3 (STK3) ELISA Kits

STK3 encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Additionally we are shipping STK3 Antibodies (97) and STK3 Proteins (15) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human STK3 STK3 6788 Q13188
Anti-Mouse STK3 STK3 56274 Q9JI10
Anti-Rat STK3 STK3 65189 O54748
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More ELISA Kits for STK3 Interaction Partners

Human serine/threonine Kinase 3 (STK3) interaction partners

  1. using an Mst2 mutation that disrupts homotypic dimerization, we showed that the monomeric Mst2-SARAH domain could form a stable complex of 1:1 stoichiometric ratio with WW45 (show SAV1 ELISA Kits) refolded under acidic pH.

  2. The MST1/2-SAV1 complex, a core component of the Hippo pathway, promotes ciliogenesis.

  3. These results suggest that AIF (show AIFM1 ELISA Kits) downregulation is a common event in kidney tumor development. AIF (show AIFM1 ELISA Kits) loss may lead to decreased STK3 activity, defective apoptosis and malignant transformation

  4. Hippo and Yap (show YAP1 ELISA Kits) regulate cardiomyocyte death and regeneration.

  5. results reveal a novel role of Mst2 in stress-dependent cardiac hypertrophy and remodeling in the adult mouse and likely human heart

  6. Results indicate that changes in phosphorylation orchestrate interactions between kinases and phosphatases in Hippo (MST1 (show MST1 ELISA Kits)/2 protein kinases) signaling, providing a putative mechanism for pathway regulation.

  7. RASSF5 (show RASSF5 ELISA Kits) can act as an inhibitor or a potential positive regulator of Mst2, depending on whether it binds to Mst2 before or after activation-loop phosphorylation.

  8. results of the present study revealed that, in addition to the phosphorylated YAP (show YAP1 ELISA Kits)/TAZ (show TAZ ELISA Kits), the Hippo pathway can suppress the Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) pathway directly through MST1 (show MST1 ELISA Kits)/2

  9. The ability of K-Ras to activate MST2 and MST2-dependent apoptosis is determined by the differential activation kinetics of mutant K-Ras and wild type K-Ras.

  10. The identification of the c-Abl (show ABL1 ELISA Kits) tyrosine kinase as a novel upstream activator of MST2 suggests that the conserved c-Abl (show ABL1 ELISA Kits)-MST (show MAP3K10 ELISA Kits) signaling cascade plays an important role in oxidative stress-induced (show SQSTM1 ELISA Kits) neuronal cell death.

Mouse (Murine) serine/threonine Kinase 3 (STK3) interaction partners

  1. Studies indicate that Hippo (Hpo (show GFER ELISA Kits); MST1 (show MST1 ELISA Kits)/2 in mammals) signaling pathway plays a central role in the cell fate-specification process.

  2. Mst2 is involved in bone homeostasis, functioning as a reciprocal regulator of osteoclast and osteoblast differentiation through the NF-kappaB (show NFKB1 ELISA Kits) pathway

  3. the TLR-Mst1 (show MST1 ELISA Kits)-Mst2-Rac (show AKT1 ELISA Kits) signaling axis is critical for effective phagosome-mitochondrion function and bactericidal activity

  4. These data indicate that that inhibition of mammalian sterile 20-like kinase 1 (show STK4 ELISA Kits) rescued cardiac fibrosis and myocardial dysfunction in chronic beta1-adrenergic receptor stimulation-induced cardiomyopathy

  5. Phosphorylation of LC3 (show MAP1LC3A ELISA Kits) by the STK3 (show PKN1 ELISA Kits) and STK4 is essential for autophagy.

  6. These results identify MST2, not MST1 (show MST1 ELISA Kits), as a critical regulator of caspase (show CASP3 ELISA Kits)-mediated photoreceptor cell death in the detached retina and indicate its potential as a future neuroprotection target.

  7. results reveal a novel role of Mst2 in stress-dependent cardiac hypertrophy and remodeling in the adult mouse and likely human heart

  8. Mst1 (show MST1 ELISA Kits)/2 regulate placental development by control of trophoblast cell differentiation and labyrinthine vasculature at midgestation and Mst1 (show MST1 ELISA Kits)/2 control labyrinth morphogenesis in trophoblast- and fetal endothelial-dependent manners.

  9. results showed that Mst1 (show MST1 ELISA Kits)/Mst2 are required for proper cardiac lineage cell development and teratoma (show DND1 ELISA Kits) formation.

  10. these findings indicate that Mst1 (show MST1 ELISA Kits)/2 are important for controlling Treg development and preventing autoimmunity in mice, but also shed new light on our understanding of Mst1 (show MST1 ELISA Kits) deficiency-mediated human immunodeficiency syndrome.

STK3 Antigen Profile

Antigen Summary

This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with STK3

  • serine/threonine kinase 3 (STK3) antibody
  • serine/threonine kinase 3 (Stk3) antibody
  • serine/threonine kinase 3 (stk3) antibody
  • serine/threonine kinase 3 (STE20 homolog, yeast) (stk3) antibody
  • 0610042I06Rik antibody
  • KRS1 antibody
  • mess1 antibody
  • MST antibody
  • mst2 antibody
  • Mst3 antibody
  • Ste20 antibody
  • wu:fc19e11 antibody
  • xstk3 antibody
  • zgc:55383 antibody

Protein level used designations for STK3

MST-2 , STE20-like kinase MST2 , mammalian STE20-like protein kinase 2 , serine/threonine kinase 3 (STE20 homolog, yeast) , serine/threonine kinase 3 (Ste20, yeast homolog) , serine/threonine-protein kinase 3 , serine/threonine-protein kinase Krs-1 , protein kinase homolog , serine/threonine kinase 3 (STE20 homolog)

GENE ID SPECIES
100060508 Equus caballus
6788 Homo sapiens
56274 Mus musculus
65189 Rattus norvegicus
432210 Xenopus laevis
425375 Gallus gallus
533815 Bos taurus
475045 Canis lupus familiaris
100524741 Sus scrofa
324125 Danio rerio
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