You are viewing an incomplete version of our website. Please click to reload the website as full version.

serine/threonine Kinase 3 Proteins (STK3)

STK3 encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Additionally we are shipping STK3 Antibodies (97) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
STK3 6788 Q13188
STK3 56274 Q9JI10
STK3 65189 O54748
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top STK3 Proteins at antibodies-online.com

Showing 9 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human Un-conjugated 5 μg Log in to see 2 to 3 Days
$336.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$246.96
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,389.83
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$3,393.50
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details
HOST_Sf-9 cells Human Un-conjugated   5 μg Log in to see 3 to 4 Days
$571.07
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

STK3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for serine/threonine Kinase 3 (STK3) Interaction Partners

Human serine/threonine Kinase 3 (STK3) interaction partners

  1. using an Mst2 mutation that disrupts homotypic dimerization, we showed that the monomeric Mst2-SARAH domain could form a stable complex of 1:1 stoichiometric ratio with WW45 (show SAV1 Proteins) refolded under acidic pH.

  2. The MST1/2-SAV1 complex, a core component of the Hippo pathway, promotes ciliogenesis.

  3. These results suggest that AIF (show AIFM1 Proteins) downregulation is a common event in kidney tumor development. AIF (show AIFM1 Proteins) loss may lead to decreased STK3 activity, defective apoptosis and malignant transformation

  4. Hippo and Yap (show YAP1 Proteins) regulate cardiomyocyte death and regeneration.

  5. results reveal a novel role of Mst2 in stress-dependent cardiac hypertrophy and remodeling in the adult mouse and likely human heart

  6. Results indicate that changes in phosphorylation orchestrate interactions between kinases and phosphatases in Hippo (MST1 (show MST1 Proteins)/2 protein kinases) signaling, providing a putative mechanism for pathway regulation.

  7. RASSF5 (show RASSF5 Proteins) can act as an inhibitor or a potential positive regulator of Mst2, depending on whether it binds to Mst2 before or after activation-loop phosphorylation.

  8. results of the present study revealed that, in addition to the phosphorylated YAP (show YAP1 Proteins)/TAZ (show TAZ Proteins), the Hippo pathway can suppress the Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) pathway directly through MST1 (show MST1 Proteins)/2

  9. The ability of K-Ras to activate MST2 and MST2-dependent apoptosis is determined by the differential activation kinetics of mutant K-Ras and wild type K-Ras.

  10. The identification of the c-Abl (show ABL1 Proteins) tyrosine kinase as a novel upstream activator of MST2 suggests that the conserved c-Abl (show ABL1 Proteins)-MST (show MAP3K10 Proteins) signaling cascade plays an important role in oxidative stress-induced (show SQSTM1 Proteins) neuronal cell death.

Mouse (Murine) serine/threonine Kinase 3 (STK3) interaction partners

  1. Studies indicate that Hippo (Hpo (show GFER Proteins); MST1 (show MST1 Proteins)/2 in mammals) signaling pathway plays a central role in the cell fate-specification process.

  2. Mst2 is involved in bone homeostasis, functioning as a reciprocal regulator of osteoclast and osteoblast differentiation through the NF-kappaB (show NFKB1 Proteins) pathway

  3. the TLR-Mst1 (show MST1 Proteins)-Mst2-Rac (show AKT1 Proteins) signaling axis is critical for effective phagosome-mitochondrion function and bactericidal activity

  4. These data indicate that that inhibition of mammalian sterile 20-like kinase 1 (show STK4 Proteins) rescued cardiac fibrosis and myocardial dysfunction in chronic beta1-adrenergic receptor stimulation-induced cardiomyopathy

  5. Phosphorylation of LC3 (show MAP1LC3A Proteins) by the STK3 (show PKN1 Proteins) and STK4 is essential for autophagy.

  6. These results identify MST2, not MST1 (show MST1 Proteins), as a critical regulator of caspase (show CASP3 Proteins)-mediated photoreceptor cell death in the detached retina and indicate its potential as a future neuroprotection target.

  7. results reveal a novel role of Mst2 in stress-dependent cardiac hypertrophy and remodeling in the adult mouse and likely human heart

  8. Mst1 (show MST1 Proteins)/2 regulate placental development by control of trophoblast cell differentiation and labyrinthine vasculature at midgestation and Mst1 (show MST1 Proteins)/2 control labyrinth morphogenesis in trophoblast- and fetal endothelial-dependent manners.

  9. results showed that Mst1 (show MST1 Proteins)/Mst2 are required for proper cardiac lineage cell development and teratoma (show DND1 Proteins) formation.

  10. these findings indicate that Mst1 (show MST1 Proteins)/2 are important for controlling Treg development and preventing autoimmunity in mice, but also shed new light on our understanding of Mst1 (show MST1 Proteins) deficiency-mediated human immunodeficiency syndrome.

STK3 Protein Profile

Protein Summary

This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with STK3

  • serine/threonine kinase 3 (STK3)
  • serine/threonine kinase 3 (Stk3)
  • serine/threonine kinase 3 (stk3)
  • serine/threonine kinase 3 (STE20 homolog, yeast) (stk3)
  • 0610042I06Rik protein
  • KRS1 protein
  • mess1 protein
  • MST protein
  • mst2 protein
  • Mst3 protein
  • Ste20 protein
  • wu:fc19e11 protein
  • xstk3 protein
  • zgc:55383 protein

Protein level used designations for STK3

MST-2 , STE20-like kinase MST2 , mammalian STE20-like protein kinase 2 , serine/threonine kinase 3 (STE20 homolog, yeast) , serine/threonine kinase 3 (Ste20, yeast homolog) , serine/threonine-protein kinase 3 , serine/threonine-protein kinase Krs-1 , protein kinase homolog , serine/threonine kinase 3 (STE20 homolog)

GENE ID SPECIES
100060508 Equus caballus
6788 Homo sapiens
56274 Mus musculus
65189 Rattus norvegicus
432210 Xenopus laevis
425375 Gallus gallus
533815 Bos taurus
475045 Canis lupus familiaris
100524741 Sus scrofa
324125 Danio rerio
Selected quality suppliers for STK3 Proteins (STK3)
Did you look for something else?