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Serine/threonine protein kinase which phosphorylates VIME. Additionally we are shipping STK33 Proteins (6) and many more products for this protein.
Showing 10 out of 115 products:
Human Polyclonal STK33 Primary Antibody for EIA, WB - ABIN954982
Mujica, Brauksiepe, Saaler-Reinhardt, Reuss, Schmidt: Differential expression pattern of the novel serine/threonine kinase, STK33, in mice and men. in The FEBS journal 2005
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Human Monoclonal STK33 Primary Antibody for IF, IP - ABIN566314
Scholl, Fröhling, Dunn, Schinzel, Barbie, Kim, Silver, Tamayo, Wadlow, Ramaswamy, Döhner, Bullinger, Sandy, Boehm, Root, Jacks, Hahn, Gilliland: Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells. in Cell 2009
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Human Monoclonal STK33 Primary Antibody for IP, ELISA - ABIN566312
Azoitei, Hoffmann, Ellegast, Ball, Obermayer, Gößele, Koch, Faber, Genze, Schrader, Kestler, Döhner, Chiosis, Glimm, Fröhling, Scholl: Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33. in The Journal of experimental medicine 2012
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Human Polyclonal STK33 Primary Antibody for EIA, IHC (p) - ABIN359942
Cantrell: Phosphoinositide 3-kinase signalling pathways. in Journal of cell science 2001
STK33 plays an essential role in hepatocellular proliferation and liver tumorigenesis. STK33 may bind directly to c-Myc (show MYC Antibodies) and increase its transcriptional activity.
Results show that STK33 is a potential oncogene (show RAB1A Antibodies) and a promising diagnostic marker for hypopharyngeal squamous cell carcinoma (HSCC). STK33 may promote tumorigenesis and progression of HSCC, and serve as a valuable molecular target for treatment of HSCC.
STK33 can promote cell migration and invasion and suppress p53 (show TP53 Antibodies) gene expression in the NL9980 and L9981 large cell lung cancer cell lines. In addition, this protein also promotes epithelial-mesenchymal transition.
The STK33-linked SNP rs4929949 is associated with obesity and BMI in two independent cohorts of Swedish and Greek children.
STK33 downregulation or dominant mutant overexpression had no effect on KRAS signaling or survival of cancer cells.
STK33/Stk33 expression pattern resembles those of some related members of the calcium/calmodulin dependent kinase (show CAMK2 Antibodies) group
Double-immunostaining experiments with antibodies against Stk33 and vimentin (show VIM Antibodies) showed a striking colocalization of Stk33 and vimentin (show VIM Antibodies) in the hypothalamus.
STK33 promotes cancer cell viability in a kinase activity-dependent manner by regulating the suppression of mitochondrial apoptosis mediated through S6K1-induced inactivation of the death agonist BAD selectively in mutant KRAS-dependent cells.
Serine/threonine protein kinase which phosphorylates VIME. May play a specific role in the dynamic behavior of the intermediate filament cytoskeleton by phosphorylation of VIME (By similarity).
serine/threonine-protein kinase 33