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Negative regulator of MAP3K1/2 signaling. Additionally we are shipping STK38 Proteins (9) and many more products for this protein.
Showing 10 out of 113 products:
Human Polyclonal STK38 Primary Antibody for EIA, WB - ABIN359159
Tamaskovic, Bichsel, Rogniaux, Stegert, Hemmings: Mechanism of Ca2+-mediated regulation of NDR protein kinase through autophosphorylation and phosphorylation by an upstream kinase. in The Journal of biological chemistry 2003
Show all 4 references for ABIN359159
Human Monoclonal STK38 Primary Antibody for IF, IHC (p) - ABIN564922
Cook, Hoa, Gomez, Gomez, Hergovich: Constitutively active NDR1-PIF kinase functions independent of MST1 and hMOB1 signalling. in Cellular signalling 2014
Show all 2 references for ABIN564922
Human Monoclonal STK38 Primary Antibody for IF, IHC (p) - ABIN564917
Zhou, Adolfs, Pijnappel, Fuller, Van der Schors, Li, Sugden, Smit, Hergovich, Pasterkamp: MICAL-1 is a negative regulator of MST-NDR kinase signaling and apoptosis. in Molecular and cellular biology 2011
Chicken Polyclonal STK38 Primary Antibody for WB - ABIN2783482
Xiao, McClatchy, Shukla, Zhao, Chen, Shenoy, Yates, Lefkowitz: Functional specialization of beta-arrestin interactions revealed by proteomic analysis. in Proceedings of the National Academy of Sciences of the United States of America 2007
Human Monoclonal STK38 Primary Antibody for RNAi, ELISA - ABIN564920
Yan, Chu, Qin, Wang, Liu, Jin, Zhang, Gomez, Hergovich, Chen, He, Gao, Yao: Regulation of NDR1 activity by PLK1 ensures proper spindle orientation in mitosis. in Scientific reports 2015
Data establish STK38 as a conserved regulator of autophagy in human cells and flies.
PLK1-mediated phosphorylation protects the binding of Mob1 to NDR1 and subsequent NDR1 activation
STK38-mediated phosphorylation of CDC25A at Ser-76 and the subsequent degradation of CDC25A are required to promote DNA damage-induced G2/M checkpoint activation.
STK38 regulates MYC (show MYC Antibodies) protein stability and turnover in a kinase activity-dependent manner. STK38 kinase inactivation abrogates apoptosis following B-cell receptor activation, whereas its silencing significantly decreases MYC (show MYC Antibodies) levels and increases apoptosis.
cyclin D1 (show CCND1 Antibodies) has a role in promoting cell cycle progression by enhancing NDR1 (show NDRG1 Antibodies)/2 kinase activity independent of Cdk4 (show CDK4 Antibodies)
17-allylamino-17-demethoxygeldanamycin down-regulates STK38, modulating radiosensitivity.
Findings suggest a function of NDR1 (show NDRG1 Antibodies), which may regulate NF-kappaB (show NFKB1 Antibodies) activation by its kinase activity.
GSK-3beta (show GSK3b Antibodies) inhibits full activation of STK38, and STK38 activation is required to prevent cell death in response to oxidative stress
Findings show a biological role for MICAL-1 (show MICAL1 Antibodies) in apoptosis and define a novel negative regulatory mechanism of MST (show MAP3K10 Antibodies)-NDR signaling.
These findings establish a novel MST3 (show STK24 Antibodies)-NDR-p21 (show CDKN1A Antibodies) axis as an important regulator of G(1)/S progression of mammalian cells.
Stk38 protein kinase (show CDK7 Antibodies) has a role in inhibiting TLR9 (show TLR9 Antibodies)-activated inflammatory responses by promoting MEKK2 (show MAP3K2 Antibodies) ubiquitination in macrophages
Findings show a biological role for MICAL-1 (show MICAL1 Antibodies) in apoptosis and define a novel negative regulatory mechanism of MST (show MSTO1 Antibodies)-NDR signaling.
reduction in the abundances of the NDR proteins NDR1 and NDR2 (show STK38L Antibodies) results in defective responses to proapoptotic stimuli, thereby facilitating the development of tumors
Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2 (By similarity).
nuclear DBF2-related kinase 1
, NDR1 protein kinase
, Ndr Ser/Thr kinase-like protein
, nuclear Dbf2-related 1
, nuclear Dbf2-related kinase 1
, serine threonine protein kinase
, serine/threonine-protein kinase 38