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Negative regulator of MAP3K1/2 signaling. Additionally we are shipping STK38 Antibodies (122) and many more products for this protein.
Showing 8 out of 9 products:
Human STK38 Protein expressed in Human - ABIN2732876
Wen, Ma, Cheng, Jiang, Xu, Zhang, Zhang, Guo, Yu, Xu, Qian, Cao, An: Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages. in Nature communications 2015
Data establish STK38 as a conserved regulator of autophagy in human cells and flies.
PLK1-mediated phosphorylation protects the binding of Mob1 to NDR1 and subsequent NDR1 activation
STK38-mediated phosphorylation of CDC25A at Ser-76 and the subsequent degradation of CDC25A are required to promote DNA damage-induced G2/M checkpoint activation.
STK38 regulates MYC (show MYC Proteins) protein stability and turnover in a kinase activity-dependent manner. STK38 kinase inactivation abrogates apoptosis following B-cell receptor activation, whereas its silencing significantly decreases MYC (show MYC Proteins) levels and increases apoptosis.
cyclin D1 (show CCND1 Proteins) has a role in promoting cell cycle progression by enhancing NDR1 (show NDRG1 Proteins)/2 kinase activity independent of Cdk4 (show CDK4 Proteins)
17-allylamino-17-demethoxygeldanamycin down-regulates STK38, modulating radiosensitivity.
Findings suggest a function of NDR1 (show NDRG1 Proteins), which may regulate NF-kappaB (show NFKB1 Proteins) activation by its kinase activity.
GSK-3beta inhibits full activation of STK38, and STK38 activation is required to prevent cell death in response to oxidative stress
Findings show a biological role for MICAL-1 (show MICAL1 Proteins) in apoptosis and define a novel negative regulatory mechanism of MST (show MAP3K10 Proteins)-NDR signaling.
These findings establish a novel MST3 (show STK24 Proteins)-NDR-p21 (show CDKN1A Proteins) axis as an important regulator of G(1)/S progression of mammalian cells.
Stk38 protein kinase (show CDK7 Proteins) has a role in inhibiting TLR9 (show TLR9 Proteins)-activated inflammatory responses by promoting MEKK2 (show MAP3K2 Proteins) ubiquitination in macrophages
Findings show a biological role for MICAL-1 (show MICAL1 Proteins) in apoptosis and define a novel negative regulatory mechanism of MST (show MSTO1 Proteins)-NDR signaling.
reduction in the abundances of the NDR proteins NDR1 and NDR2 (show STK38L Proteins) results in defective responses to proapoptotic stimuli, thereby facilitating the development of tumors
Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2 (By similarity).
nuclear DBF2-related kinase 1
, NDR1 protein kinase
, Ndr Ser/Thr kinase-like protein
, nuclear Dbf2-related 1
, nuclear Dbf2-related kinase 1
, serine threonine protein kinase
, serine/threonine-protein kinase 38