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anti-serine/threonine Kinase 4 (STK4) Antibodies

The protein encoded by STK4 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. Additionally we are shipping STK4 Proteins (16) and STK4 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
STK4 6789 Q13043
STK4 58231 Q9JI11
STK4 311622  
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Top anti-STK4 Antibodies at antibodies-online.com

Showing 10 out of 70 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ICC, IF, IP, IHC (p), WB IP Image STK4 antibody immunoprecipitates STK4 protein in IP experiments. IP samples: HepG2 whole cell extract A. 50 μg HepG2 whole cell extract B. Control with 4 μg of preimmune Rabbit IgG C. Immunoprecipitation of STK4 protein by 4 μg STK4 antibody , 7.5 % SDS-PAGE The immunoprecipitated STK4 protein was detected by STK4 antibody , diluted at 1:500. [EasyBlot anti-rabbit IgG  was used as a secondary reagent] WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 7.5% SDS PAGE antibody diluted at 1:2000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB Western blot analysis of MST-1/KRS-2 expression in Jurkat cell lysate. 100 μg Log in to see 2 to 3 Days
$283.50
Details
Mouse Rabbit Un-conjugated WB Mouse Stk4 Antibody (C-term)  western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the Stk4 antibody detected the Stk4 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to STK4 on HeLa cell (antibody concentration 25 µg/mL). STK4 monoclonal antibody (M02), clone 4F4 Western Blot analysis of STK4 expression in HeLa. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB IHC-P Image STK4 antibody detects STK4 protein at nucleus on human lung carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human lung carcinoma. STK4 antibody , dilution: 1:500. ICC/IF Image STK4 antibody detects STK4 protein at nucleus and cytoplasm by immunofluorescent analysis. Sample: PC-3 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: STK4 protein stained by STK4 antibody , diluted at 1:500. Blue: Hoechst 33342 staining. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to STK4 on HeLa cell (antibody concentration 10 µg/mL).  STK4 monoclonal antibody (M01), clone 1D7-8A10 Western Blot analysis of STK4 expression in Hela NE. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB   100 μL Log in to see 8 to 10 Days
$507.83
Details

STK4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine) ,


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Rat (Rattus)


Top referenced anti-STK4 Antibodies

  1. Human Polyclonal STK4 Primary Antibody for EIA, IHC (p) - ABIN360312 : Ren, Yan, You, Sun: Down-regulation of mammalian sterile 20-like kinase 1 by heat shock protein 70 mediates cisplatin resistance in prostate cancer cells. in Cancer research 2008 (PubMed)

More Antibodies against STK4 Interaction Partners

Human serine/threonine Kinase 4 (STK4) interaction partners

  1. Data indicate that two siblings with a serine/threonine kinase 4 (STK4) mutation with features of autosomal recessive (AR) hyperimmunoglobulin E syndrome and autoimmune cytopenias.

  2. STK4 was reduced in macrophages from human hepatoma patients and was inversely associated with the levels of IRAK1, IL-6, and phospho-p65 or phospho-STAT3. Serum STK4 levels were specifically decreased in HCC patients with high levels of IL-6.

  3. The MST1/2-SAV1 complex, a core component of the Hippo pathway, promotes ciliogenesis.

  4. the kinase Mst1 (show MST1 Antibodies) controls selective CCR7 (show CCR7 Antibodies)-dependent functions in human mature dendritic cells.

  5. Genetic inactivation of STK4 restores YAP1 (show YAP1 Antibodies) levels, triggering cell death in hematologic malignancies.

  6. Results indicate that changes in phosphorylation orchestrate interactions between kinases and phosphatases in Hippo (MST1 (show MST1 Antibodies)/2 protein kinases) signaling, providing a putative mechanism for pathway regulation.

  7. Inhibition of Mst1 (show MST1 Antibodies) kinase activation in cardiomyocytes protects against cell hypoxia.

  8. Under diabetogenic conditions, MST1 (show MST1 Antibodies) was strongly activated in beta cells, and induced apoptosis via BIM (show BCL2L11 Antibodies) upregulation, and impaired insulin (show INS Antibodies) secretion via phosphorylation of PDX1 (show PDX1 Antibodies).

  9. PHLPP1 (show PHLPP1 Antibodies) is a binding protein for Mst1 (show MST1 Antibodies) and it modulates the Hippo pathway by dephosphorylating Mst1 (show MST1 Antibodies) at the inhibitory Thr (show TRH Antibodies)(387) of Mst1 (show MST1 Antibodies).

  10. Results indicated that Mst1 (show MST1 Antibodies) might be a promising anticancer target.

Mouse (Murine) serine/threonine Kinase 4 (STK4) interaction partners

  1. Studies indicate that Hippo (Hpo (show GFER Antibodies); MST1 (show MST1 Antibodies)/2 in mammals) signaling pathway plays a central role in the cell fate-specification process.

  2. Data (including data from studies in knockout/transgenic mice) suggest Mst1 (show MST1 Antibodies) has functional roles in cytotoxic T-lymphocytes and in inhibition of tumor progression/size of T-cell lymphoma; Mst1 (show MST1 Antibodies) may be involved in tumor immunity/immunologic surveillance.

  3. the TLR-Mst1 (show MST1 Antibodies)-Mst2 (show STK3 Antibodies)-Rac (show AKT1 Antibodies) signaling axis is critical for effective phagosome-mitochondrion function and bactericidal activity

  4. Macrophage-specific Stk4 deletion resulted in chronic inflammation, liver fibrosis, and hepatomas in mice exposed to liver insult.

  5. STK4 is a novel candidate biomarker for early stage pancreatic cancer.

  6. Phosphorylation of LC3 (show MAP1LC3A Antibodies) by the STK3 (show PKN1 Antibodies) and STK4 is essential for autophagy.

  7. These results identify MST2 (show STK3 Antibodies), not MST1 (show MST1 Antibodies), as a critical regulator of caspase (show CASP3 Antibodies)-mediated photoreceptor cell death in the detached retina and indicate its potential as a future neuroprotection target.

  8. Mst1 (show MST1 Antibodies)/2 regulate placental development by control of trophoblast cell differentiation and labyrinthine vasculature at midgestation and Mst1 (show MST1 Antibodies)/2 control labyrinth morphogenesis in trophoblast- and fetal endothelial-dependent manners.

  9. Mst1 (show MST1 Antibodies) is required for Treg cells to mediate contact-dependent suppressor functions.

  10. Thioredoxin-1 (show TXN Antibodies) functions as a molecular switch to turn off the oxidative stress-induced (show SQSTM1 Antibodies) activation of MST1 (show MST1 Antibodies).

STK4 Antigen Profile

Protein Summary

The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.

Gene names and symbols associated with STK4

  • serine/threonine kinase 4 (STK4) antibody
  • serine/threonine kinase 4 (Stk4) antibody
  • serine/threonine kinase 4 (stk4) antibody
  • AI447339 antibody
  • AU020804 antibody
  • Kas-2 antibody
  • krs2 antibody
  • mst1 antibody
  • TIIAC antibody
  • ysk3 antibody

Protein level used designations for STK4

MST-1 , STE20-like kinase MST1 , dJ211D12.2 (serine/threonine kinase 4 (MST1, KRS2)) , kinase responsive to stress 2 , mammalian STE20-like protein kinase 1 , mammalian sterile 20-like 1 , serine/threonine-protein kinase 4 , serine/threonine-protein kinase Krs-2 , Yeast Sps1/Ste20-related kinase 3 , sterile 20-like kinase 1

GENE ID SPECIES
6789 Homo sapiens
58231 Mus musculus
311622 Rattus norvegicus
514886 Bos taurus
419187 Gallus gallus
717730 Macaca mulatta
398925 Xenopus laevis
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