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May be a negative regulator of NF-kappa-B and p53- mediated gene transcription (By similarity). Additionally we are shipping serine/threonine Kinase 40 Antibodies (48) and serine/threonine Kinase 40 Proteins (10) and many more products for this protein.
STK40 binds the COP1 (show CARD16 ELISA Kits) WD40 domain (show DCAF12L2 ELISA Kits) using a VPD/E motif in its C-terminal tail.
Data indicate that STK40 was a direct target of microRNA miR (show MLXIP ELISA Kits)-130a, and overexpressing miR (show MLXIP ELISA Kits)-130a significantly upregulated NF-kappaB (show NFKB1 ELISA Kits) p65 (show GORASP1 ELISA Kits), SOX9 (show SOX9 ELISA Kits), JNK (show MAPK8 ELISA Kits) and p38MAPK (show MAPK14 ELISA Kits) proteins.
identification as a negative regulator of NF-kappaB (show NFKB1 ELISA Kits)- and p53 (show TP53 ELISA Kits)-mediated gene transcription [SINK-homologous serine-threonine kinase]
Loss of Stk40 is associated with impaired fetal skeletal muscle formation.
CCAAT/enhancer-binding protein (C/EBP) beta (show CEBPB ELISA Kits) and C/EBPdelta (show CEBPD ELISA Kits), two crucial pro-adipogenic transcription factors, are controlled at a translational level by serine/threonine kinase 40 (Stk40).
the results suggested that Stk40 may be critical in the development of preimplantation embryos.
Deletion of STK40 protein in mice causes respiratory failure and death at birth
report identification of a target gene of Oct4 (show POU5F1 ELISA Kits), serine/threonine kinase 40 (Stk40), which is able to activate the Erk/MAPK (show MAPK1 ELISA Kits) pathway and induce extraembryonic-endoderm (ExEn) differentiation in mouse embryonic stem cells.
May be a negative regulator of NF-kappa-B and p53- mediated gene transcription (By similarity).
serine/threonine kinase 40
, SINK-homologous serine/threonine kinase
, serine/threonine-protein kinase 40
, serine/threonine-protein kinase 40-like
, SINK-homologous serine/threonine-protein kinase
, Ser/Thr-like kinase
, sugen kinase 495
, ortholog of Ser/Thr-like protein kinase Lyk4
, serine/threonine-protein kinase lyk4
, Ser/Thr-like protein kinase lyk4