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serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 Proteins (SERPINA3)

The protein encoded by SERPINA3 is a plasma protease inhibitor and member of the serine protease inhibitor class. Additionally we are shipping serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 Antibodies (217) and serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 Kits (26) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SERPINA3 5265 P01009
Rat SERPINA3 SERPINA3 24648 P17475
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Top serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 Proteins at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag 50 μg Log in to see 2 to 3 Days
$346.50
Details
HOST_Human Cells Human His tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_HEK-293 Human His tag 10 μg Log in to see 2 to 3 Days
$252.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$286.00
Details
HOST_Human Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$110.25
Details
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 11 to 13 Days
$457.60
Details
HOST_Human Human Un-conjugated   1 mg Log in to see 7 to 9 Days
$242.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_HEK-293 Human His tag   0.05 mg Log in to see 2 to 3 Days
$618.75
Details

SERPINA3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , ,
, ,

Top referenced serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 Proteins

  1. Human SERPINA3 Protein expressed in Human Cells - ABIN2002551 : Vila, Obach, Revilla, Oliva, Chamorro: Alpha(1)-antichymotrypsin gene polymorphism in patients with stroke. in Stroke; a journal of cerebral circulation 2000 (PubMed)
    Show all 5 references for ABIN2002551

  2. Human SERPINA3 Protein expressed in HEK-293 Cells - ABIN2181746 : Rubin, Wang, Nickbarg, McLarney, Naidoo, Schoenberger, Johnson, Cooperman: Cloning, expression, purification, and biological activity of recombinant native and variant human alpha 1-antichymotrypsins. in The Journal of biological chemistry 1990 (PubMed)
    Show all 3 references for ABIN2181746

  3. Human SERPINA3 Protein expressed in Escherichia coli (E. coli) - ABIN666908 : Tachikawa, Tsuda, Onoe, Ueno, Takagi, Shinohara: alpha-1-Antichymotrypsin gene A1252G variant (ACT Isehara-1) is associated with a lacunar type of ischemic cerebrovascular disease. in Journal of human genetics 2001 (PubMed)
    Show all 2 references for ABIN666908

More Proteins for serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) Interaction Partners

Horse (Equine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) interaction partners

Human serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) interaction partners

  1. An increased NE: A1 AT ratio is closely associated with liver Inflammation in patients with NASH (show SAMSN1 Proteins) and could serve as a novel marker to predict NASH (show SAMSN1 Proteins) in humans

  2. Urinary CD59 (show CD59 Proteins) and alpha-1 antitrypsin (show SERPINA1 Proteins) are significantly altered in hypertensive patients developing albuminuria.

  3. low serum levels of AAT (show SERPINA1A Proteins) in patients with HSAP (show MSH6 Proteins) are correlated with disease severity and AAT (show SERPINA1A Proteins) may represent a potential target for therapies aiming to improve pancreatitis.

  4. findings show that alpha-1-antitrypsin (show SERPINA1 Proteins) induces the expression of hepcidin (show HAMP Proteins) in hepatocytes probably via inhibition of alpha-1-antitrypsin (show SERPINA1 Proteins).

  5. In breast cancer patients, ER is constitutively activated, resulting in an E2-independent ER binding to the SERPINA1 (show SERPINA1 Proteins) gene and upregulation of SERPINA1 (show SERPINA1 Proteins) expression.

  6. Alpha-1 antitrypsin (show SERPINA1 Proteins) mitigates the inhibition of airway epithelial cell repair by neutrophil elastase (show ELANE Proteins).

  7. AACT is downregulated in NSCLC. The GlcNAcylated AACT can effectively differentiate Stage I non-small cell lung cancer from healthy or benign lung disease samples.

  8. The ACT gene (also named SERPINA3) was mapped on chromosome 14q32.1 We studied the association between Alpha-1 antichymotrypsin (ACT) signal peptide A/T polymorphism polymorphism and risk of primary intracerebral hemorrhage

  9. calprotectin and alpha1-antitrypsin dynamics in gastrointestinal GvHD

  10. FBG1 (show FBXO2 Proteins) degrades A1AT (show SERPINA1 Proteins)-Z through a Beclin1 (show BECN1 Proteins)-dependent arm of autophagy.

serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) Protein Profile

Protein Summary

The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

Gene names and symbols associated with SERPINA3

  • alpha-1-antichymotrypsin 1 (SERPINA3-1)
  • alpha-1-antichymotrypsin 3 (SERPINA3-3)
  • alpha-1-antichymotrypsin 2 (SERPINA3-2)
  • alpha-1-antichymotrypsin (LOC574106)
  • alpha-1-antitrypsin (SPI2)
  • alpha-1-antitrypsin (LOC100328621)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (Serpina1)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (SERPINA3)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 (SERPINA5)
  • SH2B adaptor protein 2 (Sh2b2)
  • A1A protein
  • A1AT protein
  • AACT protein
  • AAT protein
  • ACT protein
  • alpha1AT protein
  • Aps protein
  • GIG25 protein
  • LOC574106 protein
  • Pi protein
  • PI1 protein
  • Pi2 protein
  • PRO2275 protein
  • SERPINA3-1 protein
  • SERPINA3-2 protein
  • SERPINA3-3 protein
  • Spi1 protein

Protein level used designations for SERPINA3

alpha-1-antichymotrypsin 1 , alpha-1-antichymotrypsin 3 , alpha-1-antichymotrypsin 2 , alpha-1-antichymotrypsin , alpha-1-antiproteinase 2 , alpha-1-antitrypsin 2 , alpha-1-proteinase inhibitor 2 , alpha-1 protease inhibitor , alpha-1-antiproteinase , alpha-1-antitrypsin , alpha-1-antitrypsin null , protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin , serine (or cysteine) proteinase inhibitor, clade A, member 1 , serpin A1 , alpha-1-antitrypsin (protease inhibitor) , alpha-1-protease inhibitor , alpha-1-proteinase inhibitor , serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 , serine protease inhibitor alpha 1 , cell growth-inhibiting gene 24/25 protein , growth-inhibiting protein 24 , growth-inhibiting protein 25 , serine (or cysteine) proteinase inhibitor, clade A, member 3 , serpin A3 , ACT , alpha-1-antiproteinase S

GENE ID SPECIES
396684 Sus scrofa
396685 Sus scrofa
396686 Sus scrofa
574106 Macaca mulatta
100065158 Equus caballus
100328621 Oryctolagus cuniculus
5265 Homo sapiens
24648 Rattus norvegicus
397688 Sus scrofa
12 Homo sapiens
100173860 Pongo abelii
423435 Gallus gallus
100379265 Cavia porcellus
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