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Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Additionally we are shipping serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 Kits (9) and serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 Proteins (6) and many more products for this protein.
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Human Polyclonal SERPINA4 Primary Antibody for FACS, IHC (p) - ABIN391661
Chai, Chen, Chao, Chao: Kallistatin: a novel human serine proteinase inhibitor. Molecular cloning, tissue distribution, and expression in Escherichia coli. in The Journal of biological chemistry 1993
Show all 3 references for ABIN391661
KBP reduces expression of VEGF (show VEGFA Antibodies) and HIF-1alpha (show HIF1A Antibodies) nuclear translocation
Increased kallistatin levels in type 1 diabetes and its relation with carotid intima media thickness may reflect vascular dysfunction and suggest a link between micro- and macro-angiopathy.
reveal novel mechanisms of kallistatin in inducing apoptosis and autophagy in breast cancer cells
crystal structure of kallistatin 1.9 A resolution
Kallistatin protects against renal ischemia-reperfusion injury by blocking oxidative stress and renal inflammation.
Kallistatin's heparin-binding site is crucial for preventing TGF-beta (show TGFB1 Antibodies)-induced miR (show MLXIP Antibodies)-21 and oxidative stress, while its active site is key for stimulating the expression of eNOS (show NOS3 Antibodies).
Plasma kallistatin is a novel marker for severe community-acquired pneumonia prognosis.
decreased SPTBN1 (show SPTBN1 Antibodies) and kallistatin gene expression associated with decreased relapse-free survival in hepatocellular carcinoma
these findings added the knowledge for us to understand the anti-angiogenic mechanism of kallistatin, which suggested that the rhKal could be worth as a candidate compound for further development for the purpose of anti-angiogenic therapies
A novel role of kallistatin in preventing breast tumor growth and mobility by direct interaction with LRP6 (show LRP6 Antibodies).
As a potent antioxidant and anti-inflammation agent, kallistatin may also hold therapeutic promise in cardiometabolic disorders.
Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
, kallikrein inhibitor
, peptidase inhibitor 4
, protease inhibitor 4 (kallistatin)
, serpin A4