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serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 Proteins (SERPINA4)

Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Additionally we are shipping serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 Antibodies (43) and serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat SERPINA4 SERPINA4 246328  
Mouse SERPINA4 SERPINA4 321018  
SERPINA4 5267 P29622
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Top serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_HEK293 Human His tag   50 μg Log in to see 5 Days
$385.00
Details
HOST_Human Human Un-conjugated   10 μg Log in to see 11 to 14 Days
$160.55
Details

SERPINA4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,

More Proteins for serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 (SERPINA4) Interaction Partners

Mouse (Murine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 (SERPINA4) interaction partners

  1. KBP reduces expression of VEGF (show VEGFA Proteins) and HIF-1alpha (show HIF1A Proteins) nuclear translocation

Human serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 (SERPINA4) interaction partners

  1. Increased kallistatin levels in type 1 diabetes and its relation with carotid intima media thickness may reflect vascular dysfunction and suggest a link between micro- and macro-angiopathy.

  2. reveal novel mechanisms of kallistatin in inducing apoptosis and autophagy in breast cancer cells

  3. crystal structure of kallistatin 1.9 A resolution

  4. Kallistatin protects against renal ischemia-reperfusion injury by blocking oxidative stress and renal inflammation.

  5. Kallistatin's heparin-binding site is crucial for preventing TGF-beta (show TGFB1 Proteins)-induced miR (show MLXIP Proteins)-21 and oxidative stress, while its active site is key for stimulating the expression of eNOS (show NOS3 Proteins).

  6. Plasma kallistatin is a novel marker for severe community-acquired pneumonia prognosis.

  7. decreased SPTBN1 and kallistatin gene expression associated with decreased relapse-free survival in hepatocellular carcinoma

  8. these findings added the knowledge for us to understand the anti-angiogenic mechanism of kallistatin, which suggested that the rhKal could be worth as a candidate compound for further development for the purpose of anti-angiogenic therapies

  9. A novel role of kallistatin in preventing breast tumor growth and mobility by direct interaction with LRP6 (show LRP6 Proteins).

  10. As a potent antioxidant and anti-inflammation agent, kallistatin may also hold therapeutic promise in cardiometabolic disorders.

serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 (SERPINA4) Protein Profile

Protein Summary

Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.

Gene names and symbols associated with SERPINA4

  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 (Serpina4)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 (SERPINA4)
  • serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1 (Serpina4-ps1)
  • DKFZp469E1737 protein
  • KAL protein
  • kallistatin protein
  • KALps protein
  • KLST protein
  • KST protein
  • PI-4 protein
  • PI4 protein
  • SERPINA4 protein

Protein level used designations for SERPINA4

serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 , kallistatin , serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 , Kallistatin , kallikrein inhibitor , peptidase inhibitor 4 , protease inhibitor 4 (kallistatin) , serpin A4

GENE ID SPECIES
246328 Rattus norvegicus
423433 Gallus gallus
467544 Pan troglodytes
490840 Canis lupus familiaris
701846 Macaca mulatta
100172119 Pongo abelii
100586800 Nomascus leucogenys
321018 Mus musculus
5267 Homo sapiens
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