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human homolog is a serine protease inhibitor [RGD, Feb 2006].. Additionally we are shipping SERPINA12 Kits (58) and SERPINA12 Proteins (32) and many more products for this protein.
Showing 10 out of 148 products:
Human Monoclonal SERPINA12 Primary Antibody for EIA, WB - ABIN317578
Hida, Wada, Eguchi, Zhang, Baba, Seida, Hashimoto, Okada, Yasuhara, Nakatsuka, Shikata, Hourai, Futami, Watanabe, Matsuki, Hiramatsu, Akagi, Makino, Kanwar: Visceral adipose tissue-derived serine protease inhibitor: a unique insulin-sensitizing adipocytokine in obesity. in Proceedings of the National Academy of Sciences of the United States of America 2005
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Human Monoclonal SERPINA12 Primary Antibody for ELISA, WB - ABIN306427
Klöting, Berndt, Kralisch, Kovacs, Fasshauer, Schön, Stumvoll, Blüher: Vaspin gene expression in human adipose tissue: association with obesity and type 2 diabetes. in Biochemical and biophysical research communications 2005
Show all 2 references for 306427
The results of the current study indicated that vaspin inhibited the progression of atherosclerotic plaques in apoE (show APOE Antibodies)(/) mice by inhibiting endoplasmic reticulum stress-induced macrophage apoptosis.
Vaspin inhibited RANKL (show TNFSF11 Antibodies)-induced osteoclastogenesis in RAW264.7 cells and bone marrow cells.
Vaspin is a novel ligand for the cell-surface GRP78 (show HSPA5 Antibodies)/voltage-dependent anion channel complex in endothelial cells and promotes proliferation, inhibits apoptosis, and protects vascular injuries in diabetes mellitus.
Data suggest that vaspin is ligand for cell-surface GRP78 (show HSPA5 Antibodies) (glucose-regulated protein (show HSP90B1 Antibodies) 78kD)/MTJ-1 (DnaJ-like protein 1 (show DNAJC1 Antibodies)) complex; subsequent signal transduction benefits endoplasmic reticulum stress-induced metabolic dysfunctions as seen in obesity.
Study provides evidence that serum vaspin level could be regarded as the predictor for improvement of fatty liver and metabolic disturbance after laparoscopic vertical banded gastroplasty surgery in patients with severe obesity.
The minor A allele of vaspin rs2236242 polymorphism plays a protective role against obesity and diabetes among women in Upper Egypt. The serum vaspin concentration was lower in minor protective allele carriers.
In COPD (show ARCN1 Antibodies), the meta-analysis of % predicted FEV1 in cases, the strongest association was shown for a splice variant in a previously unreported region, SERPINA12 (rs140198372, pmeta=5.72x10(-6)).
Together, these data show that vaspin binds heparin with high affinity (KD = 21 +/- 2 nm) and that binding takes place at a basic patch on top of beta-sheet A and is different from other heparin-binding serpins.
In patients with diabetic nephropathy (DNP), vaspin level does not change within the early stages of DNP; while it is higher in patients with decreased glomerular filtration rate, which may be related with increasing inflammation regardless of the stage of the kidney disease.
vaspin could be visibly observed within the detectable concentrations of vaspin up to 5nM in both buffer and serum conditions. The sensitivity of this LFSA developed in this study was ranged from 0.137 to 25nM in buffer and from 0.105 to 25nM in spiked human serum, respectively. T
Vaspin acts as a coordinator of the dynamic balance between bone formation and resorption processes; its action is affected by the cytokines of the RANKL (show TNFSF11 Antibodies)/RANK/OPG (show TNFRSF11B Antibodies) system. Changes in the relationships between vaspin, bone markers, OPG (show TNFRSF11B Antibodies), and RANKL (show TNFSF11 Antibodies) might contribute to the development of osteoporosis in girls with anorexia nervosa.
These findings suggest that vaspin and VAP-1 (show AOC3 Antibodies) may play a role in the pathogenesis of psoriasis and can be used as markers of the disease; vaspin levels may reflect the severity of disease.
There was no difference in serum chemerin (show RARRES2 Antibodies), vaspin and omentin (show ITLN1 Antibodies)-1 between polycystic ovary syndrome patients and healthy controls.
Circulating vaspin levels were lower in nonalcoholic fatty liver disease.
human homolog is a serine protease inhibitor
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
, serpin A12-like
, serpin A12
, visceral adipose tissue-derived serine protease inhibitor
, visceral adipose-specific SERPIN
, serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
, serine (or cysteine) peptidase inhibitor, clade A, member 12
, serpin peptidase inhibitor, clade A, member 12
, visceral adipose tissue-derived serpin
, visceral adipose-specific serpin