serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 6 (SERPINA6) ELISA Kits

SERPINA6 encodes an alpha-globulin protein with corticosteroid-binding properties. Additionally we are shipping SERPINA6 Antibodies (140) and SERPINA6 Proteins (43) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SERPINA6 12401 Q06770
SERPINA6 866 P08185
SERPINA6 299270 P31211
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Top SERPINA6 ELISA Kits at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.073 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 13 to 16 Days
$560.00
Details
Rat 6.9 ng/mL 15.6-1000 ng/mL 96 Tests Log in to see 13 to 16 Days
$608.00
Details
Mouse 2.47 ng/mL 6.25-400 ng/mL 96 Tests Log in to see 15 to 17 Days
$891.06
Details
Pig 1.35 5 Typical standard curve 96 Tests Log in to see 15 to 18 Days
$1,026.67
Details
Human 21 1.56-100 ng/mL   96 Tests Log in to see 2 to 3 Days
$658.90
Details
Mouse 1.56-100 ng/mL   96 Tests Log in to see 2 to 3 Days
$658.90
Details
Rat
1.56-100 ng/mL   96 Tests Log in to see 2 to 3 Days
$658.90
Details
Pig
0.78-50 ng/mL   96 Tests Log in to see 2 to 3 Days
$812.90
Details
Cow
0.78-50.0 ng/mL   96 Tests Log in to see 2 to 3 Days
$812.90
Details
Monkey 1.0 ng/mL 5.0-100 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details

Top referenced SERPINA6 ELISA Kits

  1. Rat (Rattus) SERPINA6 ELISA Kit for Sandwich ELISA - ABIN433284 : Romero, Holmgren-Holm, Grasa, Esteve, Remesar, Fernández-López, Alemany: Modulation in Wistar rats of blood corticosterone compartmentation by sex and a cafeteria diet. in PLoS ONE 2013 (PubMed)
    Show all 6 references for 433284

  2. Human SERPINA6 ELISA Kit for Sandwich ELISA - ABIN415299 : Charni, Molchadsky, Goldstein, Solomon, Tal, Goldfinger, Yang, Porat, Lozano, Rotter: Novel p53 target genes secreted by the liver are involved in non-cell-autonomous regulation. in Cell death and differentiation 2016 (PubMed)

More ELISA Kits for SERPINA6 Interaction Partners

Mouse (Murine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 6 (SERPINA6) interaction partners

  1. CBG is involved in the gender differences observed in corticosteroids circulating levels and plays a role in the local regulation of corticosteroids availability in organs like lung.

  2. the same gene encodes brain and liver corticosteroid-binding globulin

  3. Data suggest fine control interaction between plasma CBG upregulation and stress-induced corticosterone (CORT (show CORT ELISA Kits)) release in mouse model of psychological stress; CBG appears to function in maintaining dynamic equilibrium between CBG-bound/-unbound CORT (show CORT ELISA Kits).

  4. Sequencing analysis showed that Cbg cDNA obtained from the mouse hypothalamus was homologous to Cbg cDNA obtained from the liver.

  5. Cbg-/- mice, unlike controls, remain insensitive to stress applied before memory retrieval. Furthermore, under stress conditions, we observed a blunted surge of corticosterone (CORT (show CORT ELISA Kits)) in plasma and no free CORT (show CORT ELISA Kits) rise in the hippocampus of Cbg-/-.

  6. study describes functional hyporesponsiveness and aldosterone resistance in distal colon of CBG(-/-) mice; steroid actions require an intrinsic but unknown function of CBG, which allows the sufficient supply of the hormone/s to the target tissue

  7. Critical role of plasma Cbg in providing an adequate endocrine and behavioral response to stress.

  8. These data suggest an active role for CBG in bioavailability, local delivery, and/or cellular signal transduction of glucocorticoids that extends beyond a function as a mere cargo transporter.

Human serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 6 (SERPINA6) interaction partners

  1. In conclusion, site-specific CBG N-glycosylation regulates the bioavailability of cortisol in inflamed environments by fine-tuning the RCL (show C6orf108 ELISA Kits) proteolysis by endogenous and exogenous elastases.

  2. The results suggest reduced CBG cleavage in central obesity, possibly contributing to the characteristic inflammatory phenotype of the central obesity and metabolic syndrome.

  3. Corticosteroid-binding globulin cleavage may be pathogen-dependent in bloodstream infection

  4. Data indicate there was no significant circadian variation in serum cortisol-binding globulin (CBG) concentration in any of the 4 groups.

  5. Human cardiomyocytes express mineralocorticoid receptors, but are mostly free of nuclear glucocorticoid receptors. CBG is expressed in myocardium and in Purkinje fibers. CBG in heart is colocalized with mineralocorticoid receptor (show NR3C2 ELISA Kits).

  6. SERPINA6-rs1998056 regulated by FOXA/ERalpha (show ESR1 ELISA Kits) might be associated with female HCC (show FAM126A ELISA Kits) risk

  7. genetic variation in the SERPINA6 gene may be associated with altered CBG levels during adolescence.

  8. the results suggest that DEX repression of Corticosteroid-binding globulin involves tethering of the glucocorticoid receptor (show NR3C1 ELISA Kits) to C/EBPb (show CEBPB ELISA Kits).

  9. 8 naturally occurring CBG mutants with abnormalities in cortisol-binding affinity, cortisol-binding capacity, production/secretion, sensitivity to proteolytic cleavage of the reactive center loop, or recognition by monoclonal antibodies used for ELISAs were identified

  10. The study investigate the half-life of intact and elastase cleaved CBG in the rabbit. The half-lives of intact and cleaved human CBG are 10 h and identical.

Pig (Porcine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 6 (SERPINA6) interaction partners

  1. non-synonymous polymorphisms of SERPINA6, particularly SNPs c.919G>A and c.44G>T/c.622C>T, are associated with cortisol level, HPA (show HPSE ELISA Kits) axis activity, and carcass and meat quality traits

  2. Cbg gene is a key regulator of cortisol levels and obesity susceptibility.

  3. Negative relationship exists between plasma cortisol and CBG under conditions of acute stress.

SERPINA6 Antigen Profile

Antigen Summary

This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events.

Gene names and symbols associated with SERPINA6

  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 (SERPINA6) antibody
  • serpin (serpina6) antibody
  • Corticosteroid-binding globulin-like (LOC100356417) antibody
  • serine (or cysteine) peptidase inhibitor, clade A, member 6 (Serpina6) antibody
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 (Serpina6) antibody
  • AI265318 antibody
  • AV104445 antibody
  • CBG antibody
  • ep45-A antibody
  • SERPINA6 antibody

Protein level used designations for SERPINA6

CBG , corticosteroid-binding globulin , serpin A6 , transcortin , serine protease inhibitor A6 , estrogen-regulated protein EP45 , serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 , corticosteroid binding globulin , serine (or cysteine) proteinase inhibitor, clade A, member 6 , serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 , serine (or cysteine) peptidase inhibitor, clade A, member 6 , serpin peptidase inhibitor, clade A, member 6

GENE ID SPECIES
100172888 Pongo abelii
373636 Xenopus laevis
453131 Pan troglodytes
490838 Canis lupus familiaris
701121 Macaca mulatta
100356417 Oryctolagus cuniculus
12401 Mus musculus
866 Homo sapiens
299270 Rattus norvegicus
396736 Sus scrofa
101118224 Ovis aries
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