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May play a role in the proliferation or differentiation of keratinocytes (By similarity).. Additionally we are shipping serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 13 Kits (5) and serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 13 Proteins (3) and many more products for this protein.
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Human Polyclonal SERPINB13 Primary Antibody for WB - ABIN2775375
Bylaite, Moussali, Marciukaitiene, Ruzicka, Walz: Expression of cathepsin L and its inhibitor hurpin in inflammatory and neoplastic skin diseases. in Experimental dermatology 2006
results suggest an important role of Cat L (show CTSL1 Antibodies) regulation by hurpin which might be of clinical relevance in human skin diseases
These data demonstrate that RUNX1 (show RUNX1 Antibodies) is an important regulator of SERPINB13 and cathepsin K (show CTSK Antibodies) activity.
Hurpin is a selective inhibitor of lysosomal cathepsin L (show CTSL1 Antibodies) and protects keratinocytes from ultraviolet-induced apoptosis.
hurpin is expressed in skin and has a possible role in inflammatory processes or the regulation of endogenous or pathogen-derived proteinase activity
Down-regulation of SERPINB13 is associated with head and neck squamous cell carcinoma
the expression of hurpin was confined mainly to the basal layer in normal skin samples, whereas hurpin was overexpressed and redistributed in diseased skin
Downregulation of SERPINB13 protein expression in HNSCC is positively associated with poor clinical outcome. Therefore, SERPINB13 seems to act as an important protease inhibitor involved in the progression of HNSCC.
May play a role in the proliferation or differentiation of keratinocytes (By similarity).
serpin peptidase inhibitor, clade B (ovalbumin), member 5
, serpin peptidase inhibitor, clade B (ovalbumin), member 13
, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 13
, serpin peptidase inhibitor, clade B, member 13
, serpin B13-like
, serpin B13
, UV-B repressed sequence, HUR 7
, haCaT UV-repressible serpin
, peptidase inhibitor 13
, protease inhibitor 13 (hurpin, headpin)
, proteinase inhibitor 13
, serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13