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anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) Antibodies

SERPINB9 encodes a member of the serine protease inhibitor family which are also known as serpins. Additionally we are shipping SERPINB9 Proteins (6) and SERPINB9 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SERPINB9 361241  
SERPINB9 20723  
SERPINB9 5272 P50453
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Top anti-SERPINB9 Antibodies at antibodies-online.com

Showing 10 out of 110 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN190825 (0.5µg/ml) staining of Human Placenta lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Mouse Un-conjugated FACS, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$324.50
Details
Human Mouse Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated WB SERPINB9 Antibody (Center) (ABIN1881792) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the SERPINB9 antibody detected the SERPINB9 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$336.00
Details
Human Mouse Un-conjugated FACS, IHC (fro), WB   0.1 mg Log in to see 6 to 8 Days
$533.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from COLO/HuvEc/Jurkat cells, using SERPINB9 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using SERPINB9 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated IF, IHC (p), WB   1 mL Log in to see 6 to 8 Days
$533.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details

SERPINB9 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)
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Mouse (Murine)
,

Human , , , ,
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Top referenced anti-SERPINB9 Antibodies

  1. Human Polyclonal SERPINB9 Primary Antibody for WB - ABIN1881792 : Sprecher, Morgenstern, Mathewes, Dahlen, Schrader, Foster, Kisiel: Molecular cloning, expression, and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors. in The Journal of biological chemistry 1996 (PubMed)
    Show all 6 references for ABIN1881792

  2. Human Monoclonal SERPINB9 Primary Antibody for FACS, IHC (p) - ABIN180930 : Hirst, Buzza, Bird, Warren, Cameron, Zhang, Ashton-Rickardt, Bird: The intracellular granzyme B inhibitor, proteinase inhibitor 9, is up-regulated during accessory cell maturation and effector cell degranulation, and its overexpression enhances CTL potency. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 4 references for ABIN180930

  3. Human Monoclonal SERPINB9 Primary Antibody for FACS, IHC (fro) - ABIN264518 : Hirst, Buzza, Sutton, Trapani, Loveland, Bird: Perforin-independent expression of granzyme B and proteinase inhibitor 9 in human testis and placenta suggests a role for granzyme B-mediated proteolysis in reproduction. in Molecular human reproduction 2001 (PubMed)
    Show all 2 references for ABIN264518

  4. Human Polyclonal SERPINB9 Primary Antibody for ELISA, WB - ABIN190825 : Jiang, Ellison, Alarid, Shapiro: Interplay between the levels of estrogen and estrogen receptor controls the level of the granzyme inhibitor, proteinase inhibitor 9 and susceptibility to immune surveillance by natural killer cells. in Oncogene 2007 (PubMed)

  5. Human Monoclonal SERPINB9 Primary Antibody for IF, IHC (p) - ABIN1108971 : Bladergroen, Meijer, ten Berge, Hack, Muris, Dukers, Chott, Kazama, Oudejans, van Berkum, Kummer: Expression of the granzyme B inhibitor, protease inhibitor 9, by tumor cells in patients with non-Hodgkin and Hodgkin lymphoma: a novel protective mechanism for tumor cells to circumvent the immune system? in Blood 2001 (PubMed)

More Antibodies against SERPINB9 Interaction Partners

Pig (Porcine) serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) interaction partners

Mouse (Murine) serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) interaction partners

  1. Data suggest that reactive oxygen species (ROS (show ROS1 Antibodies)) generated within cytotoxic lymphocytes by receptor stimulation are required for lysosomal permeabilization and release of GzmB (granzyme B (show Gzmb Antibodies)) into the cytosol and for inactivation of serpin B9.

  2. the negative regulation of DC priming of CD8 (show CD8A Antibodies) T lymphocyte immunity by CTL killing is mitigated by the physiological inhibition of GrB by Spi6.

  3. SPI-CI (show OVA Antibodies) is a novel immune escape molecule that acts in concert with SPI (show CHGA Antibodies)-6 to prevent cytotoxic lymphocyte-mediated killing of tumor cells.

  4. Estrogen induction of PI-9 may reduce the ability of cytolytic lymphocytes-mediated immune surveillance to destroy newly transformed cells

  5. In mCAP3 (show ST14 Antibodies), an intact catalytic triad was necessary for activation of ENaC (show SCNN1A Antibodies) but not for intramolecular cleavage of the protease.

  6. protects hepatocytes against excessively vigorous granzyme B (show Gzmb Antibodies)-dependent killing but may also delay immune clearance of virally infected hepatocytes

  7. deficiency in a weak intracellular inhibitor of neutrophil elastase (show ELANE Antibodies) results in an acute inflammatory response that protects from P. aeruginosa but does not cause lung disease

  8. SPI (show CHGA Antibodies)-6 is selectively up-regulated in hepatocytes in response to infiltration of the liver by NK cells that express perforin (show PRF1 Antibodies) and enzymatically active granzyme B (show Gzmb Antibodies).

  9. Increased SPI (show CHGA Antibodies)-6 expression is not sufficient to confer lipopolysaccharide-treated dendritic cells with resistance to direct killing in vivo.

Human serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) interaction partners

  1. Data show that oropharyngeal squamous cell carcinomas (OPSCCs) express granzyme inhibitors SERPINB1 (show SERPINB1 Antibodies), SERPINB4 (show SERPINB4 Antibodies) and SERPINB9 for cytotoxicity and the expression was not different between human papillomavirus (HPV)-positive and HPV-negative tumors.

  2. Pediatric CNS-PNETs evade immune recognition by downregulating cell surface MHC (show HLAE Antibodies)-I and CD1d (show CD1D Antibodies) expression. Intriguingly, expression of SERPINB9, SERPINB1 (show SERPINB1 Antibodies), and SERPINB4 (show SERPINB4 Antibodies) is acquired during tumorigenesis in 29%, 29%, and 57% of the tumors

  3. Data suggest that reactive oxygen species (ROS (show ROS1 Antibodies)) generated within cytotoxic lymphocytes by receptor stimulation are required for lysosomal permeabilization and release of GzmB (granzyme B (show Gzmb Antibodies)) into the cytosol and for inactivation of serpin B9.

  4. Increased intracellular PI-9 activity in mononuclear phagocytes from HIV-infected patients contributes to successful intracellular infection by virulent Mycobacterium tuberculosis.

  5. Suppression of granzyme B (show Gzmb Antibodies) initiated apoptosis in protease inhibitor-9-expressing leukemia cells.

  6. SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3 (show TLR3 Antibodies), MDA5 (show IFIH1 Antibodies) and RIG-I (show DDX58 Antibodies) during subclinical rejection.

  7. lung cancer cells utilise their increased PI-9 expression to protect from granzyme B (show Gzmb Antibodies)-mediated cytotoxicity as an immune evasion mechanism

  8. Inhibition of Granzyme B (show Gzmb Antibodies) by PI-9 protects prostate cancer cells from apoptosis.

  9. PI-9 induction within human mononuclear phagocytes by virulent Mycobacterium tuberculosis serves to protect these primary targets of infection from elimination by apoptosis and thereby promotes intracellular survival of the organism.

  10. constitutive expression of serine protease inhibitor 9 (PI-9) on human peripheral blood-and bone marrow-derived mesenchymal stem cells is a major defense mechanism against granzyme B (show Gzmb Antibodies)-mediated destruction by NK cells

SERPINB9 Antigen Profile

Protein Summary

This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6.

Gene names and symbols associated with SERPINB9

  • serpin peptidase inhibitor, clade B (ovalbumin), member 9 (Serpinb9) antibody
  • serpin peptidase inhibitor, clade B (ovalbumin), member 9 (SERPINB9) antibody
  • serine (or cysteine) peptidase inhibitor, clade B, member 9 (Serpinb9) antibody
  • BB283241 antibody
  • CAP-3 antibody
  • CAP3 antibody
  • ovalbumin antibody
  • PI-9 antibody
  • PI9 antibody
  • SERPINB9 antibody
  • Spi6 antibody

Protein level used designations for SERPINB9

serine (or cysteine) peptidase inhibitor, clade B, member 9 , serpin B9 , serpin peptidase inhibitor, clade B (ovalbumin), member 9 , serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9 , Cytoplasmic antiproteinase 3 , serpin B9-like , serine (or cysteine) proteinase inhibitor, clade B, member 9 , serine protease inhibitor 6 , cytoplasmic antiproteinase 3 , peptidase inhibitor 9 , protease inhibitor 9 (ovalbumin type) , serpin peptidase inhibitor, clade B, member 9

GENE ID SPECIES
361241 Rattus norvegicus
488192 Canis lupus familiaris
524513 Bos taurus
707580 Macaca mulatta
744242 Pan troglodytes
100126851 Sus scrofa
100388662 Callithrix jacchus
100445070 Pongo abelii
100596895 Nomascus leucogenys
20723 Mus musculus
5272 Homo sapiens
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