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anti-serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2) Antibodies

SERPINE2 encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Additionally we are shipping SERPINE2 Kits (11) and SERPINE2 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SERPINE2 20720 Q07235
SERPINE2 29366 P07092
SERPINE2 5270 P07093
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Top anti-SERPINE2 Antibodies at antibodies-online.com

Showing 10 out of 115 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SERPINE2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate Host: Rabbit  Target Name: SERPINE2  Sample Tissue: Human Fetal Liver  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB SERPINE2 Antibody (Center)  western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the SERPINE2 antibody detected the SERPINE2 protein (arrow). SERPINE2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SERPINE2 Antibody (Center) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human brain tissue stained with SERPINE2 antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of SERPINE2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. Western blot analysis using SERPINE2 Antibody (Center) Cat.-No AP53863PU-N in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the SERPINE2 antibody detected the SERPINE2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells transfected with either RC204904 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-SERPINE2 antibody (ABIN2455736), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SERPINE2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SERPINE2. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SERPINE2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SERPINE2. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SERPINE2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SERPINE2. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC204904 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-SERPINE2 antibody (ABIN2455738), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SERPINE2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SERPINE2. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC204904 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-SERPINE2 antibody (ABIN2455780), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SERPINE2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SERPINE2. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Mouse Un-conjugated WB Western Blot analysis of SERPINE2 expression in transfected 293T cell line by SERPINE2 monoclonal antibody (M01), clone 3G12. Lane 1: SERPINE2 transfected lysate(44.002 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of SERPINE2 expression in transfected 293T cell line by SERPINE2 monoclonal antibody (M01), clone 3G12.Lane 1: SERPINE2 transfected lysate(44.002 KDa).Lane 2: Non-transfected lysate. Western Blot detection against Immunogen (36.85 KDa) . 100 μg Log in to see 9 Days
$430.00
Details

SERPINE2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SERPINE2 Antibodies

  1. Human Polyclonal SERPINE2 Primary Antibody for EIA, IHC (p) - ABIN954749 : Hersh, Pillai, Zhu, Lomas, Bakke, Gulsvik, DeMeo, Klanderman, Lazarus, Litonjua, Sparrow, Reilly, Agusti, Calverley, Donner, Levy, Make, Paré, Rennard, Vestbo, Wouters, Scholand, Coon, Hoidal, Silverman: Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene. in American journal of respiratory and critical care medicine 2010 (PubMed)
    Show all 3 references for ABIN954749

  2. Human Polyclonal SERPINE2 Primary Antibody for WB - ABIN2786838 : Demeo, Campbell, Barker, Brantly, Eden, McElvaney, Rennard, Sandhaus, Stocks, Stoller, Strange, Turino, Silverman: IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency. in American journal of respiratory cell and molecular biology 2007 (PubMed)

  3. Human Polyclonal SERPINE2 Primary Antibody for IHC (p), WB - ABIN656538 : Bianchini, Qi, Alvarez, Iwamoto, Coutant, Ibrahim, Valero, Cristofanilli, Green, Radvanyi, Hatzis, Hortobagyi, Andre, Gianni, Symmans, Pusztai: Molecular anatomy of breast cancer stroma and its prognostic value in estrogen receptor-positive and -negative cancers. in Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010 (PubMed)

More Antibodies against SERPINE2 Interaction Partners

Cow (Bovine) serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2) interaction partners

  1. stage-dependent regulation of granulosa cell PA and SerpinE2 production, consistent with a role in extracellular matrix remodeling during follicle growth.

  2. SERPINE2 is involved in the regulation of atresia in bovine follicles

  3. SERPINE2 expression is dynamically regulated in granulosa cells during dominant follicle development

Rhesus Monkey serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2) interaction partners

  1. Prostasin (show PRSS8 Antibodies) may be involved in follicular development, ovulation, and CL formation, whereas PN-1 (show SCN9A Antibodies) may be present to regulate the proteolysis in these processes.[prostasin (show PRSS8 Antibodies); protease nexin-1]

Mouse (Murine) serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2) interaction partners

  1. the involvement of PAI-1 (show SERPINE1 Antibodies) in HIF-1 (show HIF1A Antibodies)-enhanced thrombosis and that an additional factor participates in regulating Pai-1 (show SERPINE1 Antibodies) expression in compressed skin.

  2. aberrant Serpine2/Pn-1 is required for proliferation of human and mouse medulloblastoma cells.

  3. PN-1 (show SCN9A Antibodies) strongly limits physiological angiogenesis.

  4. The PAI-1 (show SERPINE1 Antibodies) inhibitor not only accelerated the expansion of the donor HSCs during the early-stage of regeneration, but also supported long-term hematopoiesis.

  5. a novel inhibitory interaction between CAP1/Prss8 (show PRSS8 Antibodies) and nexin-1, opening the search for specific CAP1/Prss8 (show PRSS8 Antibodies) antagonists that are independent of its catalytic activity

  6. SERPINE2 and PLAU (show PLAU Antibodies) are involved in cumulus expansion and oocyte maturation.

  7. Endothelial protease nexin-1 is a novel regulator of A disintegrin and metalloproteinase 17 (show ADAM17 Antibodies) maturation and endothelial protein C receptor (show PROCR Antibodies) shedding via furin (show FURIN Antibodies) inhibition.

  8. PN1 (show SCN9A Antibodies) regulates Hh signaling by decreasing protein levels of the Hh ligand Sonic (SHH (show SHH Antibodies)) and its downstream effectors.

  9. PN-1 (show SCN9A Antibodies) has direct antiangiogenic properties and is a yet-unrecognized player in the angiogenic balance

  10. SERPINE2 protein may play a role as a sperm decapacitation factor.

Human serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2) interaction partners

  1. together, these data demonstrate that SERPINE2 might prevent cartilage catabolism by inhibiting the expression of MMP-13 (show MMP13 Antibodies), one of the most relevant collagenases, involved in cartilage breakdown in OA.

  2. The results suggest that the rs3795879 polymorphism of SERPINE2 is not a risk factor for chronic obstructive pulmonary disease.

  3. aberrant Serpine2/Pn-1 is required for proliferation of human and mouse medulloblastoma cells.

  4. Our findings indicate that upregulated SERPINE2 may contribute to the aggressive phenotype of gastric cancer and suggest that SERPINE2 can be used as a novel prognostic factor and anticancer target in patients with gastric cancer.

  5. MAGI2 (show MAGI2 Antibodies), SERPINE2, and NT5C3B expression levels are associated with airway wall thickening and additionally with bronchial inflammation, emphysema, and lung function, respectively, all features of chronic obstructive pulmonary disease.

  6. Haplotypes carrying major alleles of rs729631 (C), rs975278 (G), rs7583463 (C) of SERPINE2 had protective effect on lung function amongst South Indian male smokers with COPD (show ARCN1 Antibodies).

  7. SERPINE2 and PLAU (show PLAU Antibodies) are involved in cumulus expansion and oocyte maturation.

  8. Endothelial protease nexin-1 is a novel regulator of A disintegrin and metalloproteinase 17 (show ADAM17 Antibodies) maturation and endothelial protein C receptor (show PROCR Antibodies) shedding via furin (show FURIN Antibodies) inhibition.

  9. Studies suggest that protease nexin 1 as a marker of prostate cancer.

  10. PN1 regulates Hh signaling by decreasing protein levels of the Hh ligand Sonic (SHH (show SHH Antibodies)) and its downstream effectors.

SERPINE2 Antigen Profile

Protein Summary

This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SERPINE2

  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (SERPINE2) antibody
  • nexin-1 (PN-1) antibody
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (serpine2) antibody
  • serine (or cysteine) peptidase inhibitor, clade E, member 2 (Serpine2) antibody
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (Serpine2) antibody
  • B230326M24Rik antibody
  • GDN antibody
  • GDNPF antibody
  • Gdnpn1 antibody
  • MGC143011 antibody
  • PAI-1 antibody
  • PI-7 antibody
  • PI7 antibody
  • Pn-1 antibody
  • PN1 antibody
  • PNI antibody
  • SERPINE2 antibody
  • Spi4 antibody
  • Spin4 antibody

Protein level used designations for SERPINE2

plasminogen activator inhibitor type 1, member 2 , serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 , serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 , protease nexin-1 , glia-derived nexin-like , GDN , glia-derived nexin , peptidase inhibitor 7 , protease nexin 1 , protease nexin I , serine (or cysteine) proteinase inhibitor, clade E, member 2 , serine protease inhibitor 4 , serine protease-inhibitor 4 , serpin E2 , Glia-derived nexin/protease nexin I , plasminogen activator inhibitor type 1 , protease nexin PN-1 , serine (or cysteine) peptidase inhibitor, clade E, member 2 , serpin peptidase inhibitor, clade E, member 2 , glial-derived neurite promoting factor

GENE ID SPECIES
282521 Bos taurus
397542 Sus scrofa
459980 Pan troglodytes
707121 Macaca mulatta
100411540 Callithrix jacchus
100559583 Anolis carolinensis
100596009 Nomascus leucogenys
20720 Mus musculus
29366 Rattus norvegicus
5270 Homo sapiens
608930 Canis lupus familiaris
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