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serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 Proteins (SERPINE2)

SERPINE2 encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Additionally we are shipping SERPINE2 Antibodies (115) and SERPINE2 Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SERPINE2 20720 Q07235
SERPINE2 29366 P07092
SERPINE2 5270 P07093
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Top SERPINE2 Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag 25 μg Log in to see 2 to 3 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_HEK-293 Human Un-conjugated   10 μg Log in to see 2 to 3 Days
$294.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,039.67
Details
HOST_HEK-293 Human His tag   0.025 mg Log in to see 2 to 3 Days
$584.38
Details
Insect Cells Mouse Un-conjugated   0.1 mg Log in to see 2 to 3 Days
$649.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SERPINE2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Rat (Rattus)

Human , , , ,
,

Top referenced SERPINE2 Proteins

  1. Human SERPINE2 Protein expressed in HEK-293 Cells - ABIN2181749 : Gloor, Odink, Guenther, Nick, Monard: A glia-derived neurite promoting factor with protease inhibitory activity belongs to the protease nexins. in Cell 1987 (PubMed)
    Show all 2 references for ABIN2181749

More Proteins for serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2) Interaction Partners

Cow (Bovine) serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2) interaction partners

  1. stage-dependent regulation of granulosa cell PA and SerpinE2 production, consistent with a role in extracellular matrix remodeling during follicle growth.

  2. SERPINE2 is involved in the regulation of atresia in bovine follicles

  3. SERPINE2 expression is dynamically regulated in granulosa cells during dominant follicle development

Rhesus Monkey serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2) interaction partners

  1. Prostasin (show PRSS8 Proteins) may be involved in follicular development, ovulation, and CL formation, whereas PN-1 (show SCN9A Proteins) may be present to regulate the proteolysis in these processes.[prostasin (show PRSS8 Proteins); protease nexin-1]

Mouse (Murine) serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2) interaction partners

  1. the involvement of PAI-1 (show SERPINE1 Proteins) in HIF-1 (show HIF1A Proteins)-enhanced thrombosis and that an additional factor participates in regulating Pai-1 (show SERPINE1 Proteins) expression in compressed skin.

  2. aberrant Serpine2/Pn-1 is required for proliferation of human and mouse medulloblastoma cells.

  3. PN-1 (show SCN9A Proteins) strongly limits physiological angiogenesis.

  4. The PAI-1 (show SERPINE1 Proteins) inhibitor not only accelerated the expansion of the donor HSCs during the early-stage of regeneration, but also supported long-term hematopoiesis.

  5. a novel inhibitory interaction between CAP1/Prss8 (show PRSS8 Proteins) and nexin-1, opening the search for specific CAP1/Prss8 (show PRSS8 Proteins) antagonists that are independent of its catalytic activity

  6. SERPINE2 and PLAU (show PLAU Proteins) are involved in cumulus expansion and oocyte maturation.

  7. Endothelial protease nexin-1 is a novel regulator of A disintegrin and metalloproteinase 17 (show ADAM17 Proteins) maturation and endothelial protein C receptor (show PROCR Proteins) shedding via furin (show FURIN Proteins) inhibition.

  8. PN1 (show SCN9A Proteins) regulates Hh signaling by decreasing protein levels of the Hh ligand Sonic (SHH (show SHH Proteins)) and its downstream effectors.

  9. PN-1 (show SCN9A Proteins) has direct antiangiogenic properties and is a yet-unrecognized player in the angiogenic balance

  10. SERPINE2 protein may play a role as a sperm decapacitation factor.

Human serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2) interaction partners

  1. together, these data demonstrate that SERPINE2 might prevent cartilage catabolism by inhibiting the expression of MMP-13 (show MMP13 Proteins), one of the most relevant collagenases, involved in cartilage breakdown in OA.

  2. The results suggest that the rs3795879 polymorphism of SERPINE2 is not a risk factor for chronic obstructive pulmonary disease.

  3. aberrant Serpine2/Pn-1 is required for proliferation of human and mouse medulloblastoma cells.

  4. Our findings indicate that upregulated SERPINE2 may contribute to the aggressive phenotype of gastric cancer and suggest that SERPINE2 can be used as a novel prognostic factor and anticancer target in patients with gastric cancer.

  5. MAGI2 (show MAGI2 Proteins), SERPINE2, and NT5C3B expression levels are associated with airway wall thickening and additionally with bronchial inflammation, emphysema, and lung function, respectively, all features of chronic obstructive pulmonary disease.

  6. Haplotypes carrying major alleles of rs729631 (C), rs975278 (G), rs7583463 (C) of SERPINE2 had protective effect on lung function amongst South Indian male smokers with COPD (show ARCN1 Proteins).

  7. SERPINE2 and PLAU (show PLAU Proteins) are involved in cumulus expansion and oocyte maturation.

  8. Endothelial protease nexin-1 is a novel regulator of A disintegrin and metalloproteinase 17 (show ADAM17 Proteins) maturation and endothelial protein C receptor (show PROCR Proteins) shedding via furin (show FURIN Proteins) inhibition.

  9. Studies suggest that protease nexin 1 as a marker of prostate cancer.

  10. PN1 regulates Hh signaling by decreasing protein levels of the Hh ligand Sonic (SHH (show SHH Proteins)) and its downstream effectors.

SERPINE2 Protein Profile

Protein Summary

This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SERPINE2

  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (SERPINE2)
  • nexin-1 (PN-1)
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (serpine2)
  • serine (or cysteine) peptidase inhibitor, clade E, member 2 (Serpine2)
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (Serpine2)
  • B230326M24Rik protein
  • GDN protein
  • GDNPF protein
  • Gdnpn1 protein
  • MGC143011 protein
  • PAI-1 protein
  • PI-7 protein
  • PI7 protein
  • Pn-1 protein
  • PN1 protein
  • PNI protein
  • SERPINE2 protein
  • Spi4 protein
  • Spin4 protein

Protein level used designations for SERPINE2

plasminogen activator inhibitor type 1, member 2 , serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 , serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 , protease nexin-1 , glia-derived nexin-like , GDN , glia-derived nexin , peptidase inhibitor 7 , protease nexin 1 , protease nexin I , serine (or cysteine) proteinase inhibitor, clade E, member 2 , serine protease inhibitor 4 , serine protease-inhibitor 4 , serpin E2 , Glia-derived nexin/protease nexin I , plasminogen activator inhibitor type 1 , protease nexin PN-1 , serine (or cysteine) peptidase inhibitor, clade E, member 2 , serpin peptidase inhibitor, clade E, member 2 , glial-derived neurite promoting factor

GENE ID SPECIES
282521 Bos taurus
397542 Sus scrofa
459980 Pan troglodytes
707121 Macaca mulatta
100411540 Callithrix jacchus
100559583 Anolis carolinensis
100596009 Nomascus leucogenys
20720 Mus musculus
29366 Rattus norvegicus
5270 Homo sapiens
608930 Canis lupus familiaris
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