serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) ELISA Kits

The protein encoded by SERPINF1 is a member of the serpin family, although it does not display the serine protease inhibitory activity shown by many of the other serpin family members. Additionally we are shipping serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 Antibodies (168) and serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 Proteins (64) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SERPINF1 57104 Q96AD5
SERPINF1 20317 P97298
SERPINF1 287526  
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Top serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 ELISA Kits at antibodies-online.com

Showing 10 out of 73 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Rat 0.062 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 13 to 16 Days
$608.00
Details
Human 1.25 ng/mL 3.12-200 ng/mL 96 Tests Log in to see 13 to 16 Days
$560.00
Details
Mouse 0.055 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 13 to 16 Days
$576.00
Details
Cow 0.135 ng/mL 0.312-20 ng/mL 96 Tests Log in to see 15 to 17 Days
$1,014.01
Details
Pig 0.025 ng/mL 0.05-10 ng/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$1,107.33
Details
Human 0.6 0.6 96 Tests Log in to see 2 to 3 Days
$476.30
Details
Human 0.91 ng/mL 0.312-20 ng/mL   96 Tests Log in to see 2 to 3 Days
$658.90
Details
Rat 1.56-100 ng/mL   96 Tests Log in to see 2 to 3 Days
$658.90
Details
Rabbit 250 pg/mL 500-8000 pg/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$1,081.67
Details
Mouse
1.56-100 ng/mL   96 Tests Log in to see 2 to 3 Days
$658.90
Details

Top referenced serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 ELISA Kits

  1. Human SERPINF1 ELISA Kit for Sandwich ELISA - ABIN415117 : Hou, Liang, Wang, Zhang, Wang, Shi, Dong, Cai: A therapeutic strategy for choroidal neovascularization based on recruitment of mesenchymal stem cells to the sites of lesions. in Molecular therapy : the journal of the American Society of Gene Therapy 2010 (PubMed)
    Show all 6 references for 415117

  2. Mouse (Murine) SERPINF1 ELISA Kit for Sandwich ELISA - ABIN415701 : Liang, Hou, Yi, Yang, Gu, Lau, Gao, Ma, Lu, Wei, Pei, Yi: Increased expression of pigment epithelium-derived factor in aged mesenchymal stem cells impairs their therapeutic efficacy for attenuating myocardial infarction injury. in European heart journal 2013 (PubMed)
    Show all 5 references for 415701

  3. Rat (Rattus) SERPINF1 ELISA Kit for Sandwich ELISA - ABIN432444 : Yang, Luo, Zhou, Lv, Liu, Zhang, Gao, Chen, Xia, Luo, Cheng, Li: Rosiglitazone inhibits expression and secretion of PEDF in adipose tissue and liver of male SD rats via a PPAR-? independent mechanism. in Endocrinology 2014 (PubMed)

More ELISA Kits for serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 Interaction Partners

Horse (Equine) serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. data suggest that PEDF, via its potent antiangiogenic capabilities, may contribute to superior healing in wounds on the trunks of horses by protecting from excessive formation of vascular granulation tissue

Human serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. PEDF expression in retinal endothelial cells plays a key role in modulation of cell proliferation, migration, and capillary morphogenesis.

  2. study found that PEDF binds to the C1q head regions and activates the classical complement pathway; in addition, observed that in synovial fluid (SF) from rheumatoid arthritis patients, PEDF forms detectable complexes with C4d, which are present in a range of concentrations; SF from nonarthritic donors consistently contained little or no C4d-PEDF complexes

  3. PEDF is a hormone-regulated negative autocrine mediator of endometrial proliferation.

  4. Findings suggest that PEDF plays a critical role in preventing hypoxia/reoxygenation injury by modulating anti-oxidant and anti-apoptotic factors and promoting autophagy.

  5. PEDF is associated with increased epithelial-mesenchymal transition in bladder cancer

  6. Six rare heterozygous SERPINF1 variants were found in seven patients in our familial otosclerosis cohort; three are missense mutations predicted to be deleterious to protein function

  7. Excessive amount of PEDF50 in myopic specimens have been shown to correlate with the abrogated PEDF processing rather than with an increase of its expression. Moreover, immunohistochemical staining of the myopic Tenon's capsule tissue sections revealed the halo of deposited PEDF50 in the fibroblast extracellular space.

  8. Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) pathway may mediate ox-LDL-induced endothelial injury via oxidative stress, and PEDF ameliorates endothelial injury by suppressing Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) pathway and subsequently reducing oxidative stress.

  9. Oxidative stress decreased the levels of PNPLA2 transcripts with no effect on ALOX5 expression. Exogenous additions of P1 peptide or overexpression of the PNPLA2 gene decreased both LTB4 levels and death of RPE cells undergoing oxidative stress.

  10. Furthermore, pigment epithelium-derived factor (PEDF), a secreted glycoprotein known for its anti-tumor properties, blocked Wnt3a (show WNT3A ELISA Kits)-directed induction of autophagy proteins. Autophagy inhibition was complemented by reciprocal regulation of the oxidative stress enzymes, superoxide dismutase 2 (SOD2 (show SOD2 ELISA Kits)) and catalase (show CAT ELISA Kits).

Mouse (Murine) serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. PEDF deficiency has a significant impact on retinal endothelial cell adhesion and migration through altered production of extracellular matrix and junctional proteins in response to increased oxidative stress affecting their proangiogenic activity.

  2. PEDF is a hormone-regulated negative autocrine mediator of endometrial proliferation.

  3. These results indicate that PEDF counters Wnt (show WNT2 ELISA Kits) signaling to allow for osteoblast differentiation and provides a mechanistic insight into how the PEDF null state results in OI type VI.

  4. Furthermore, pigment epithelium-derived factor (PEDF), a secreted glycoprotein known for its anti-tumor properties, blocked Wnt3a (show WNT3A ELISA Kits)-directed induction of autophagy proteins. Autophagy inhibition was complemented by reciprocal regulation of the oxidative stress enzymes, superoxide dismutase 2 (SOD2 (show SOD2 ELISA Kits)) and catalase (show CAT ELISA Kits).

  5. Study demonstrated the inhibitory effect of PEDF on insulin (show INS ELISA Kits)-dependent molecular mechanisms of glucose homeostasis, and suggests that PEDF could be a specific target in the management of metabolic disorders.

  6. Alpha-2-Antiplasmin (show Alpha2 Antiplasmin ELISA Kits) mediated myofibroblast formation and the development of renal fibrosis in unilateral ureteral obstruction via induction of TGF-beta (show TGFB1 ELISA Kits).

  7. PEDF inhibits retinal microvascular dysfunction induced by 12/15-lipoxygenase-derived eicosanoids in diabetic retinopathy.

  8. Data suggest that pigment epithelium-derived factor (PEDF) and adipose triglyceride lipase (ATGL (show PNPLA2 ELISA Kits)) may serve as therapeutic targets for managing vascular hyperpermeability in sepsis.

  9. describe alterations in the PEDF signaling pathway and subventricular zone stem cell self-renewal at a very young age, which could be involved in the premature senescence observed in the SAM (show TTN ELISA Kits)-P8 model

  10. The combination of rAAV-PEDF with hyperthermia has synergistic therapeutic effects on established solid tumors, with no side effects.

Pig (Porcine) serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. After cryotherapy of the sclera, pigment epithelium-derived factor levels increased 44.8% compared to untreated controlsand stayed at that level until day 14. It returned to baseline by day 21. (untreated).

  2. the inhibitory effect of PEDF appears to be mediated via the processing of VEGF-R2 by gamma-secretase

Cow (Bovine) serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. PEDF inhibits key steps in the angiogenic response of retinal capillary endothelial cells, including cell proliferation and vascular tubule formation. Gene expression of PEDF is negatively regulated by glucose, insulin (via mTOR) and VEGF.

  2. Results suggest that leptin (show LEP ELISA Kits) might elicit angiogenesis through vascular endothelial growth factor induction as well as pigment epithelium-derived factor suppression in pericytes.

  3. PEDF promotes growth of pericytes through autocrine production of PDGFB.

  4. PEDF and VEGFR-1 (show FLT1 ELISA Kits) have roles in the negative regulation of angiogenesis

serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the serpin family, although it does not display the serine protease inhibitory activity shown by many of the other serpin family members. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells.

Gene names and symbols associated with SERPINF1

  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (serpinf1) antibody
  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (SERPINF1) antibody
  • patatin-like phospholipase domain containing 2 (PNPLA2) antibody
  • serine (or cysteine) peptidase inhibitor, clade F, member 1 (Serpinf1) antibody
  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (Serpinf1) antibody
  • 1110001C14Rik antibody
  • AI195227 antibody
  • ATGL antibody
  • Dmrs91 antibody
  • EPC-1 antibody
  • iPLA2zeta antibody
  • MGC82984 antibody
  • OI6 antibody
  • OI12 antibody
  • Pedf antibody
  • PEDF-R antibody
  • Pedfl antibody
  • Sdf3 antibody
  • SERPINF1 antibody
  • TTS-2.2 antibody
  • TTS2 antibody

Protein level used designations for SERPINF1

serine (or cysteine) proteinase inhibitor, clade F), member 1 , serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 , pigment epithelium derived factor , serine (or cysteine) proteinase inhibitor, clade F, member 1 , serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 , pigment epithelium-derived factor , serpin peptidase inhibitor, clade F, member 1 , pigment epithelium-derived factor-like , IPLA2-zeta , TTS2.2 , adipose triglyceride lipase , calcium-independent phospholipase A2 , desnutrin , patatin-like phospholipase domain containing protein 2 , patatin-like phospholipase domain-containing protein 2 , transport-secretion protein 2.2 , triglyceride hydrolase , SDF-3 , alpha-2 antiplasmin , caspin , serpin F1 , serpin-F1 , stromal cell derived factor 3 , stromal cell-derived factor 3 , cell proliferation-inducing gene 35 protein , serine (or cysteine) peptidase inhibitor, clade F, member 1 , alpha-2 antiplasmin, pigment epithelium derived factor

GENE ID SPECIES
394686 Xenopus (Silurana) tropicalis
444412 Xenopus laevis
468137 Pan troglodytes
771608 Gallus gallus
100072415 Equus caballus
100403187 Callithrix jacchus
100457889 Pongo abelii
100482247 Ailuropoda melanoleuca
100580793 Nomascus leucogenys
57104 Homo sapiens
20317 Mus musculus
100216362 Cavia porcellus
5176 Homo sapiens
287526 Rattus norvegicus
780402 Sus scrofa
611276 Canis lupus familiaris
281386 Bos taurus
100192425 Ovis aries
417561 Gallus gallus
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