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SGK3 is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. Additionally we are shipping serum/glucocorticoid Regulated Kinase Family, Member 3 Proteins (12) and many more products for this protein.
Showing 10 out of 121 products:
Human Polyclonal SGK3 Primary Antibody for IHC (p), WB - ABIN1882132
Brickley, Mikosz, Hagan, Conzen: Ubiquitin modification of serum and glucocorticoid-induced protein kinase-1 (SGK-1). in The Journal of biological chemistry 2002
Show all 6 references for ABIN1882132
Human Polyclonal SGK3 Primary Antibody for IHC (p), WB - ABIN392462
Okada, Ishii, Masujin, Yasoshima, Matsuda, Ogura, Nakayama, Kunieda, Doi: The critical roles of serum/glucocorticoid-regulated kinase 3 (SGK3) in the hair follicle morphogenesis and homeostasis: the allelic difference provides novel insights into hair follicle biology. in The American journal of pathology 2006
Show all 2 references for ABIN392462
Rat (Rattus) Polyclonal SGK3 Primary Antibody for WB - ABIN610994
Collas, Le Guellec, Taskén: The A-kinase-anchoring protein AKAP95 is a multivalent protein with a key role in chromatin condensation at mitosis. in The Journal of cell biology 2000
Show all 2 references for ABIN610994
Chicken Polyclonal SGK3 Primary Antibody for IHC, WB - ABIN2786285
Slagsvold, Marchese, Brech, Stenmark: CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4. in The EMBO journal 2006
SGK3 is a positive regulator of KCNA5 (show KCNA5 Antibodies), which is at least partially effective by abrogating the effect of Nedd4-2 (show NEDD4L Antibodies).
SGK3 contributes to the regulation of store-operated calcium entry into and migration of dendritic cells.
SGK3 plays a previously unappreciated role in glucose homeostasis, likely through direct effects within pancreatic beta-cells, to stimulate proliferation and insulin (show INS Antibodies) release
The study identifies SGK3 as a novel endosomal kinase that acutely regulates Na(+)/H(+) exchanger 3 (NHE3 (show SLC9A3 Antibodies)) in a PI3K-dependent mechanism.
SGK3 has a subtle but significant role in the regulation of renal tubular phosphate transport and bone density.
Data suggest that SGK3 is critical for proper mast cell function.
SGK3 plays an important role in postnatal hair follicle development as illustrated by SGK3 knockout mice. The hair defect is linked to reduced proliferation and reduced nuclear accumulation of beta catenin (show CTNNB1 Antibodies) in hair bulb keratinocytes.
SGK3 is differentially regulated in hippocampus after contextual fear conditioning & reactivation of the context-shock memory. Consolidation changes are recapitulated during reconsolidation. Retrieval-induced transcription depends on memory remoteness.
SGK3, and to a lesser extent SGK2 (show SGK2 Antibodies), but not SGK1 (show SGK1 Antibodies), increase glutamate (show GRIN1 Antibodies)-induced currents by increasing the abundance of GluR1 (show GRIA1 Antibodies) protein in the cell membrane
SGK3 is required for adequate intestinal Na(+) coupled glucose transport and impaired glucose absorption may contribute to delayed growth and decreased plasma glucose concentrations of SGK3 deficient mice.
Data show that activation of serum- and glucocorticoid-regulated kinase 3 (SGK3) plays an important role in inositol polyphosphate 4-phosphatase type II (INPP4B (show INPP4B Antibodies))-mediated melanoma cell proliferation.
It is unlikely that SGK3 plays a significant role for oncogenic signalling in multiple myeloma.
SGK3 is a key mediator of PDK1 (show PDK1 Antibodies) activity in melanoma.
VPS34 (show PIK3C3 Antibodies)-IN1 will provide a useful tool to decipher the kinase-dependent functions of Vps34 (show PIK3C3 Antibodies), with acute changes in SGK3 phosphorylation and subcellular localization being new biomarkers of Vps34 (show PIK3C3 Antibodies) activity
Breast cancers harboring oncogenic PIK3CA (show PIK3CA Antibodies) activate SGK3 signaling while suppressing Akt (show AKT1 Antibodies), indicative of oncogenic functions for both INPP4B (show INPP4B Antibodies) and SGK3 in these tumors.
SGK3 is an androgen receptor (AR (show AR Antibodies)) target and induces cell proliferation through the AR-SGK3-p70S6K (show RPS6KB1 Antibodies)-cyclin D1 (show CCND1 Antibodies) pathway in prostate cancer cells.
SGK3 is a novel regulator of K(ir)2.1.
SGK3 stability and kinase activation are regulated by the Hsp90 (show HSP90 Antibodies)-Cdc37 (show CDC37 Antibodies) chaperone complex.
SGK1,3 enhances the expression level of mature hERG (show KCNH2 Antibodies) channels by inhibiting Nedd4-2 (show NEDD4L Antibodies) as well as by promoting Rab11 (show RAB11A Antibodies)-mediated hERG (show KCNH2 Antibodies) recycling.
A positive correlation between SGK3 expression and breast tumor prognosis.
This gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
serine/threonine-protein kinase Sgk3
, cytokine-independent survival kinase
, serine/threonine protein kinase CISK
, serum/glucocorticoid-regulated kinase 3
, serum/glucocorticoid regulated kinase 3
, serum glucocorticoid regulated kinase 3