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anti-tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) Antibodies

TRDMT1 encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. Additionally we are shipping tRNA Aspartic Acid Methyltransferase 1 Proteins (9) and tRNA Aspartic Acid Methyltransferase 1 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TRDMT1 1787 O14717
TRDMT1 13434 O55055
TRDMT1 291324 Q4G073
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Top anti-tRNA Aspartic Acid Methyltransferase 1 Antibodies at antibodies-online.com

Showing 10 out of 139 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-Dnmt2 Pab (ABIN387859) in Jurkat cell lysate (Lane A) and mouse liver tissue lysate (Lane B). Dnmt2 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-mDnmt2 Pab (ABIN387906) in HL-60 cell lysate. mDnmt2 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to DNMT2 on HeLa cell (antibody concentration 40 µg/mL). Western Blot analysis of DNMT2 expression in transfected 293T cell line by DNMT2 monoclonal antibody (M01), clone 1E12. Lane 1: DNMT2 transfected lysate(45 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Mouse Mouse Un-conjugated IHC (p), WB Human Thymus (formalin-fixed, paraffin-embedded) stained with TRDMT1 antibody ABIN290198 at 5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Mouse Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 2 to 3 Days
$262.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details

TRDMT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-tRNA Aspartic Acid Methyltransferase 1 Antibodies

  1. Human Polyclonal TRDMT1 Primary Antibody for IHC (p), WB - ABIN387859 : Hermann, Schmitt, Jeltsch: The human Dnmt2 has residual DNA-(cytosine-C5) methyltransferase activity. in The Journal of biological chemistry 2003 (PubMed)
    Show all 6 references for ABIN387859

  2. Human Monoclonal TRDMT1 Primary Antibody for IF, WB - ABIN393425 : Vivekanandan, Daniel, Kannangai, Martinez-Murillo, Torbenson: Hepatitis B virus replication induces methylation of both host and viral DNA. in Journal of virology 2010 (PubMed)
    Show all 5 references for ABIN393425

  3. Human Polyclonal TRDMT1 Primary Antibody for EIA, IHC (p) - ABIN356546 : Franchina, Hooper, Kay: Five novel alternatively spliced transcripts of DNA (cytosine-5) methyltransferase 2 in human peripheral blood leukocytes. in The international journal of biochemistry & cell biology 2001 (PubMed)
    Show all 5 references for ABIN356546

  4. Human Polyclonal TRDMT1 Primary Antibody for IHC (p), WB - ABIN387906 : Yoder, Bestor: A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast. in Human molecular genetics 1998 (PubMed)
    Show all 2 references for ABIN387906

  5. Human Polyclonal TRDMT1 Primary Antibody for EIA, IHC (p) - ABIN356589 : Okano, Xie, Li: Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells. in Nucleic acids research 1998 (PubMed)
    Show all 2 references for ABIN356589

  6. Chicken Polyclonal TRDMT1 Primary Antibody for WB - ABIN2783440 : Matakidou, El Galta, Rudd, Webb, Bridle, Eisen, Houlston: Prognostic significance of folate metabolism polymorphisms for lung cancer. in British journal of cancer 2007 (PubMed)

More Antibodies against tRNA Aspartic Acid Methyltransferase 1 Interaction Partners

Human tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) interaction partners

  1. The strong effect of some of the somatic cancer mutations on DNMT2 activity suggests that these mutations have a functional role in tumorigenesis.

  2. DNMT1 (show DNMT1 Antibodies), DNMT2 and DNMT3A (show DNMT3A Antibodies) may play important roles in gastric cancer carcinogenesis.

  3. Mapped is the tRNA binding site of DNMT2 by systematically mutating surface-exposed lysine and arginine residues to alanine and studying the tRNA methylation activity and binding of the corresponding variants.

  4. the role of Dnmt2 in stress granules could represent a primitive cellular defense mechanism against viral infection.

  5. The expression of DNMT1 (show DNMT1 Antibodies), DNMT2, DNMT3A (show DNMT3A Antibodies) and DNMT3B (show DNMT3B Antibodies) in pediatric acute lymphoblastic leukemia patients, was investigated.

  6. Hepatitis B virus-induced overexpression of DNMTs leads to viral DNA methylation (show HELLS Antibodies) and decreased viral gene expression and also leads to methylation of host CpG islands.

  7. cDNA microarray analysis identified several genes involved in DNA methylation (show HELLS Antibodies), such as DNMT2 and DNMT3a (show DNMT3A Antibodies) that were more highly expressed in LNCaP-r (an androgen sensitive prostate cancer cell line).

  8. genetic and biochemical approach revealed that DNMT2 did not methylate DNA but instead methylated aspartic acid transfer RNA (tRNA(Asp (show ASIP Antibodies))) and that DNMT2 specifically methylated cytosine 38 in the anticodon loop

  9. An association study of 45 folate-related genes in spina bifida: Involvement of tRNA aspartic acid methyltransferase 1 (TRDMT1)

Mouse (Murine) tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) interaction partners

  1. Dnmt2 plays an important role in haematopoiesis and define a novel function of C38 (show CEND1 Antibodies) tRNA methylation in the discrimination of near-cognate codons, thereby ensuring accurate polypeptide synthesis.

  2. these findings uncover a novel function of Dnmt2 in RNA-mediated epigenetic heredity

  3. Dnmt2-dependent methylomes lack defined DNA methylation (show HELLS Antibodies) patterns.

  4. Steady-state levels of unmethylated tRNAs were substantially reduced, and loss of Dnmt2 and NSun2 (show NSUN2 Antibodies) was further associated with reduced rates of overall protein synthesis.

  5. the role of Dnmt2 in stress granules could represent a primitive cellular defense mechanism against viral infection.

tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) Antigen Profile

Protein Summary

This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa.

Gene names and symbols associated with TRDMT1

  • tRNA aspartic acid methyltransferase 1 (trdmt1) antibody
  • tRNA aspartic acid methyltransferase 1 (LOC100230580) antibody
  • tRNA aspartic acid methyltransferase 1 (TRDMT1) antibody
  • tRNA aspartic acid methyltransferase 1 (Trdmt1) antibody
  • DMNT2 antibody
  • dnmt2 antibody
  • MGC89267 antibody
  • MHSAIIP antibody
  • PUMET antibody
  • RNMT1 antibody
  • Rnmt2 antibody

Protein level used designations for TRDMT1

tRNA aspartic acid methyltransferase 1 , DNA (cytosine-5)-methyltransferase-like protein 2 , DNA MTase homolog HsaIIP , DNA methyltransferase-2 , tRNA (cytosine(38)-C(5))-methyltransferase , tRNA (cytosine-5-)-methyltransferase , DNA MTase homolog MmuIIP , DNA methyltransferase 2 , DNA methyltransferase homolog MmuIIP , m.MmuIIP , met-2 , DNA (cytosine-5-)-methyltransferase 2

GENE ID SPECIES
448379 Xenopus (Silurana) tropicalis
100230580 Taeniopygia guttata
100346643 Oryctolagus cuniculus
100407322 Callithrix jacchus
100463906 Ailuropoda melanoleuca
100605724 Nomascus leucogenys
1787 Homo sapiens
13434 Mus musculus
379360 Xenopus laevis
420520 Gallus gallus
487116 Canis lupus familiaris
100302362 Sus scrofa
353353 Bos taurus
291324 Rattus norvegicus
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