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Participates both in methylation of protein and tRNA species. Additionally we are shipping TRMT112 Antibodies (21) and TRMT112 Proteins (6) and many more products for this protein.
The localization of the TRMT112 protein is determined by WBSCR22 (show WBSCR22 ELISA Kits), and the WBSCR22 (show WBSCR22 ELISA Kits)-TRMT112 complex is localized in the cell nucleus.
DIMT1L (show DIMT1 ELISA Kits) and WBSCR22 (show WBSCR22 ELISA Kits)-TRMT112 are required for distinct pre-rRNA processing reactions leading to synthesis of 18S rRNA. Ribosome biogenesis requires the presence of the modification enzyme rather than its RNA-modifying catalytic activity.
Participates both in methylation of protein and tRNA species. The heterodimer with HEMK2/N6AMT1 catalyzes N5- methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species (By similarity).
, tRNA methyltransferase 11-2 homolog
, tRNA methyltransferase 112 homolog