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Participates both in methylation of protein and tRNA species. Additionally we are shipping TRMT112 Antibodies (20) and many more products for this protein.
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The localization of the TRMT112 protein is determined by WBSCR22 (show WBSCR22 Proteins), and the WBSCR22 (show WBSCR22 Proteins)-TRMT112 complex is localized in the cell nucleus.
DIMT1L (show DIMT1 Proteins) and WBSCR22 (show WBSCR22 Proteins)-TRMT112 are required for distinct pre-rRNA processing reactions leading to synthesis of 18S rRNA. Ribosome biogenesis requires the presence of the modification enzyme rather than its RNA-modifying catalytic activity.
Participates both in methylation of protein and tRNA species. The heterodimer with HEMK2/N6AMT1 catalyzes N5- methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species (By similarity).
, tRNA methyltransferase 11-2 homolog
, tRNA methyltransferase 112 homolog