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tRNA Nucleotidyl Transferase, CCA-Adding, 1 Proteins (Trnt1)

The CCA-adding enzyme TRNT1 (EC 2.7.7.25) is an essential enzyme that catalyzes the addition of the CCA terminus to the 3-prime end of tRNA precursors. Additionally we are shipping Trnt1 Antibodies (11) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Trnt1 51095 Q96Q11
Rat Trnt1 Trnt1 312616  
Trnt1 70047 Q8K1J6
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Top Trnt1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

Trnt1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for tRNA Nucleotidyl Transferase, CCA-Adding, 1 (Trnt1) Interaction Partners

Human tRNA Nucleotidyl Transferase, CCA-Adding, 1 (Trnt1) interaction partners

  1. two non-syndromic retinitis pigmentosa pedigrees with segregating mutations in TRNT1

  2. The clinical phenotypes associated with TRNT1 mutations are largely due to impaired mitochondrial translation, resulting from defective CCA (show FBN2 Proteins) addition to mitochondrial tRNA(Ser (show SIGLEC1 Proteins)(AGY)).

  3. Tandem CCA (show FBN2 Proteins) addition is not the result of a modified enzymatic activity that is particular to unstable RNAs. Rather, it is a consequence of the natural activity of the CCA (show FBN2 Proteins)-adding enzyme on a substrate with increased conformational flexibility, the CCA (show FBN2 Proteins)-adding enzyme is able to trigger the degradation of potentially detrimental small RNAs and tRNAs.

  4. The patient-associated TRNT1 mutations result in partial loss of function of TRNT1 and lead to metabolic defects in both the mitochondria and cytosol, which can account for the phenotypic pleiotropy.

  5. human gene transcript CGI-47 (#AF151805) was cloned and encodes a bona fide CCA (show FBN2 Proteins)-adding enzyme and not a poly(A) polymerase (show PAPOLA Proteins).

  6. These findings strongly suggest that the splice variant of the human CCA (show FBN2 Proteins)-adding enzyme is expressed in the cell although the in vivo function remains unclear.

  7. is a RNA polymerase which newly adds CCA (show FBN2 Proteins) sequence to tRNA 3'terminal. This reaction was named as Vice-Anchored Knock-in and Lock Dynamics.[review]

Trnt1 Protein Profile

Protein Summary

The CCA-adding enzyme TRNT1 (EC 2.7.7.25) is an essential enzyme that catalyzes the addition of the CCA terminus to the 3-prime end of tRNA precursors. This reaction is a fundamental prerequisite for mature tRNAs to become aminoacylated and to participate in protein biosynthesis (Lizano et al., 2007

Gene names and symbols associated with Trnt1

  • tRNA nucleotidyl transferase, CCA-adding, 1 (TRNT1)
  • tRNA nucleotidyl transferase, CCA-adding, 1 (trnt1)
  • tRNA nucleotidyl transferase, CCA-adding, 1 (Trnt1)
  • 2410043H24Rik protein
  • 2610044E04Rik protein
  • 9830143O18Rik protein
  • AA408384 protein
  • bMtCCA protein
  • C76540 protein
  • CCA1 protein
  • CGI-47 protein
  • mt-Trat protein
  • MtCCA protein
  • TRNT1 protein
  • zgc:86645 protein

Protein level used designations for Trnt1

CCA tRNA nucleotidyltransferase 1, mitochondrial , tRNA-nucleotidyltransferase , tRNA-nucleotidyltransferase 1, mitochondrial , tRNA nucleotidyl transferase, CCA-adding, 1 , tRNA-nucleotidyltransferase 1, mitochondrial-like , mitochondrial CCA-adding tRNA-nucleotidyltransferase , mitochondrial tRNA nucleotidyl transferase, CCA-adding , mt CCA-adding enzyme , mt tRNA CCA-diphosphorylase , mt tRNA CCA-pyrophosphorylase , mt tRNA adenylyltransferase , tRNA adenylyltransferase, mitochondrial

GENE ID SPECIES
407144 Bos taurus
415249 Danio rerio
734914 Xenopus laevis
476552 Canis lupus familiaris
394602 Xenopus (Silurana) tropicalis
470735 Pan troglodytes
704550 Macaca mulatta
100053009 Equus caballus
100074783 Ornithorhynchus anatinus
100153838 Sus scrofa
100414825 Callithrix jacchus
100449831 Pongo abelii
100479227 Ailuropoda melanoleuca
100585151 Nomascus leucogenys
51095 Homo sapiens
312616 Rattus norvegicus
70047 Mus musculus
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