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tau Tubulin Kinase 2 Proteins (TTBK2)

TTBK2 encodes a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. Additionally we are shipping TTBK2 Antibodies (63) and TTBK2 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TTBK2 140810 Q3UVR3
Rat TTBK2 TTBK2 311349  
TTBK2 146057 Q6IQ55
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Top TTBK2 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Baculovirus infected Insect Cells Mouse GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details

TTBK2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human ,
,

More Proteins for tau Tubulin Kinase 2 (TTBK2) Interaction Partners

Mouse (Murine) tau Tubulin Kinase 2 (TTBK2) interaction partners

  1. Study shows that TTBK2 is a dedicated regulator of the initiation of cili (show USP14 Proteins)ogenesis in vivo; TTBK2 acts at the distal end of the basal body, where it promotes the removal of CP110, which caps the mother centriole, and promotes recruitment of intraflagellar transport proteins.

Human tau Tubulin Kinase 2 (TTBK2) interaction partners

  1. TTBK1 (show Ttbk1 Proteins)/2 kinases may represent attractive targets for therapeutic intervention for TDP-43 (show TARDBP Proteins) proteinopathies such as Amyotrophic lateral sclerosis and Frontotemporal lobar degeneration-TDP.

  2. TTBK2 is a multifunctional kinase involved in important cellular processes and demands augmented efforts in investigating its functions

  3. TTBK2 phosphorylates KIF2A (show KIF2A Proteins) and antagonizes KIF2A (show KIF2A Proteins)-induced depolymerization at microtubules plus ends for cell migration.

  4. TTBK2 bound EB1 and Cep164 through its SxIP motifs and a proline-rich motif, respectively.

  5. data suggest that TTBK2 also acts upstream of Cep164, contributing to the assembly of distal appendages

  6. Dominant truncating mutations in human TTBK2 cause spinocerebellar ataxia (show USP14 Proteins) type 11 (SCA11); these mutant proteins do not promote ciliogenesis and inhibit ciliogenesis in wild-type cells.

  7. TTBK2 is a completely novel regulator of Na(+)-coupled glucose transport.

  8. findings reveals a major role of PRKX (show PRKX Proteins), TTBK2 and RSK4 (show RPS6KA6 Proteins) in triggering Sunitinib resistance formation; data suggest transcriptional regulation of these kinases together with other proteins might play an important role in formation of Sunitinib resistance by affecting transcription factors

  9. two-basepair deletion (c.1306_1307delGA, p.D435fs448X in exon 12) lead to a premature stop codon in the TTBK2 gene; spinocerebellar ataxia (show USP14 Proteins) patients had phenotypic of slowly progressive almost pure cerebellar ataxia (show USP14 Proteins) with normal life expectancy

  10. Examination the TTBK2 gene in 68 unrelated spinocerebellar ataxia (show USP14 Proteins) patients displayed the normal elution profile, which denoted that no disease-related mutation was identified. We provided the evidence that SCA11 is a rare form of ataxia (show USP14 Proteins) in China.

TTBK2 Protein Profile

Protein Summary

This gene encodes a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. Mutations in this gene cause spinocerebellar ataxia type 11 (SCA11)\; a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem.

Gene names and symbols associated with tau Tubulin Kinase 2 Proteins (TTBK2)

  • tau tubulin kinase 2 (TTBK2)
  • tau tubulin kinase 2 (ttbk2)
  • tau tubulin kinase 2 (Ttbk2)
  • 2610507N02Rik protein
  • AI326283 protein
  • B930008N24Rik protein
  • MGC146331 protein
  • mKIAA0847 protein
  • SCA11 protein
  • TTBK protein
  • Ttbk1 protein
  • TTK protein

Protein level used designations for tau Tubulin Kinase 2 Proteins (TTBK2)

tau tubulin kinase 2 , tau-tubulin kinase 2 , protein bartleby , tau tubulin kinase 1

GENE ID SPECIES
423241 Gallus gallus
453368 Pan troglodytes
487520 Canis lupus familiaris
541215 Bos taurus
780299 Xenopus (Silurana) tropicalis
100056539 Equus caballus
100546498 Meleagris gallopavo
100555047 Anolis carolinensis
140810 Mus musculus
311349 Rattus norvegicus
146057 Homo sapiens
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