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thromboxane A Synthase 1 (Platelet) Proteins (TBXAS1)

TBXAS1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping thromboxane A Synthase 1 (Platelet) Antibodies (71) and thromboxane A Synthase 1 (Platelet) Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TBXAS1 6916 P24557
TBXAS1 21391 P36423
Rat TBXAS1 TBXAS1 24886 P49430
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Top thromboxane A Synthase 1 (Platelet) Proteins at antibodies-online.com

Showing 6 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TBXAS1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
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More Proteins for thromboxane A Synthase 1 (Platelet) (TBXAS1) Interaction Partners

Human thromboxane A Synthase 1 (Platelet) (TBXAS1) interaction partners

  1. the administration of salted drinking water (2.7% NaCl) to wild-type mice resulted in elevated placental TXA2 synthase (TXAS) and plasma thromboxane A2, but not prostacyclin, levels, which was also found in clinical preeclampsia placenta samples.

  2. Single nucleotide polymorphisms of TBXAS1 are associated with susceptibility to gout in ethnic Han males population.

  3. The cardiovascular events significantly morefrequently occurred during 12 and 18 months in resistant diabetics and in the patients with an allele lacking the *2/*3 CYP2C9 (show CYP2C9 Proteins) gene function and AT/TT polymorphism of the thromboxane synthase gene TBS1.

  4. The carriage of Thromboxane A synthase 1 gene polymorphism AA was shown to affect the risk of clopidogrel resistance.

  5. study suggests that the anti-tumor effect of glycyrrhizin in lung adenocarcinoma is, at least in part, TxAS-dependent.

  6. 12-HHT (show ACVRL1 Proteins) is produced by both TxAS-dependent and TxAS-independent pathways in vitro and in vi

  7. In this study we have showed, for the first time, a significant role of the minor allele rs6962291 of TBXAS1 in patients with NSAID acute cutaneous hypersensitivity.

  8. The increased Km and decreased Vmax values observed with L357V suggest that this variant may generate less TXA2 at the low levels of PGH2 expected in vivo, raising the possibility of attenuated signaling through the thromboxane pathway.

  9. Data show that that DNA methylation (show HELLS Proteins) of the TBXAS1 promoter was decreased and thromboxane synthase expression was increased in omental arteries of preeclamptic women as compared with normal pregnant women.

  10. these results showed that visfatin (show NAMPT Proteins) promoted IL-8 (show IL8 Proteins) production by upregulation of TXAS, leading to angiogenic activation in endothelial cells.

Mouse (Murine) thromboxane A Synthase 1 (Platelet) (TBXAS1) interaction partners

  1. the administration of salted drinking water (2.7% NaCl) to wild-type mice resulted in elevated placental TXA2 synthase (TXAS) and plasma thromboxane A2, but not prostacyclin, levels, which was also found in clinical preeclampsia placenta samples.

  2. 12-HHT (show ACVRL1 Proteins) is produced by both TxAS-dependent and TxAS-independent pathways in vitro and in vi

  3. TXAS mRNA expression was increased within the vascular wall in mouse models of atherosclerosis with advanced lesions.

  4. thromboxane synthase, prostacyclin synthase and thromboxane receptor have roles in atherosclerotic lesions and correlate with plaque composition

thromboxane A Synthase 1 (Platelet) (TBXAS1) Protein Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TBXAS1

  • thromboxane-A synthase (PTRG_00454)
  • thromboxane-A synthase (PTRG_06796)
  • Thromboxane-A synthase (thas)
  • thromboxane A synthase 1 (platelet) (TBXAS1)
  • thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) (tbxas1)
  • thromboxane A synthase 1, platelet (Tbxas1)
  • BDPLT14 protein
  • CYP5 protein
  • CYP5A1 protein
  • GHOSAL protein
  • TBXAS1 protein
  • THAS protein
  • TS protein
  • TXAS protein
  • TXS protein
  • wu:fk19d08 protein
  • zgc:136708 protein

Protein level used designations for TBXAS1

thromboxane-A synthase , Thromboxane-A synthase , thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) , thromboxane A synthase 1 (platelet) , thromboxane-A synthase-like , TXA synthase , cytochrome P450 5A1 , cytochrome P450, family 5, subfamily A, polypeptide 1 , platelet, cytochrome P450, subfamily V , TXS , thromboxane A synthase 1, platelet , ThromboxA ane synthase 1

GENE ID SPECIES
6338652 Pyrenophora tritici-repentis Pt-1C-BFP
6345060 Pyrenophora tritici-repentis Pt-1C-BFP
100306773 Salmo salar
418101 Gallus gallus
463774 Pan troglodytes
482771 Canis lupus familiaris
711748 Macaca mulatta
792041 Danio rerio
100173366 Pongo abelii
100481563 Ailuropoda melanoleuca
100580072 Nomascus leucogenys
6916 Homo sapiens
397112 Sus scrofa
509326 Bos taurus
21391 Mus musculus
24886 Rattus norvegicus
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