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tyrosine Hydroxylase Proteins (TH)

The protein encoded by TH is involved in the conversion of tyrosine to dopamine. Additionally we are shipping tyrosine Hydroxylase Antibodies (324) and tyrosine Hydroxylase Kits (55) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TH 7054 P07101
TH 21823 P24529
TH 25085 P04177
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Top tyrosine Hydroxylase Proteins at

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Mouse His tag 50 μg Log in to see 16 Days
HOST_Baculovirus infected Insect Cells Human His tag 50 μg Log in to see 16 Days
Yeast Schistosoma mansoni His tag   1 mg Log in to see 56 to 66 Days
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
Yeast Dog His tag   1 mg Log in to see 56 to 66 Days
Yeast Anguilla anguilla His tag   1 mg Log in to see 56 to 66 Days
HOST_Escherichia coli (E. coli) Rat His tag,S tag   100 μg Log in to see 11 to 13 Days
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 9 to 19 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

TH Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

Rat (Rattus)

Top referenced tyrosine Hydroxylase Proteins

  1. Mouse (Murine) TH Protein expressed in Baculovirus infected Insect Cells - ABIN2008493 : Daubner, Le, Wang: Tyrosine hydroxylase and regulation of dopamine synthesis. in Archives of biochemistry and biophysics 2011 (PubMed)

More Proteins for tyrosine Hydroxylase (TH) Interaction Partners

Fruit Fly (Drosophila melanogaster) tyrosine Hydroxylase (TH) interaction partners

  1. The Khc73 stalk/14-3-3 (show YWHAZ Proteins)/NudE pathway defines a physical connection that coordinates the activities of multiple motor proteins to precisely position the spindle.

  2. role of 14-3-3epsilon in germ cell migration

  3. 14-3-3epsilon acts as a biochemical control point for axon guidance in Drosophila, silencing Plexin A repulsive axon guidance and regulating a semaphorin repulsion/integrin adhesion switch.

  4. We conclude that 14-3-3epsilon is required for Rab11 (show RAB11A Proteins)-positive vesicle function, which in turn enables antimicrobial peptide (show cAMP Proteins) secretion during an innate immune response.

  5. Hpo (show GFER Proteins) signaling inhibited Yki (show YAP1 Proteins) nuclear localization and activity by phosphorylating Yki (show YAP1 Proteins) and both isoforms of 14-3-3 (show YWHAZ Proteins), 14-3-3varepsilon and 14-3-3zeta (show YWHAZ Proteins), regulate Yki (show YAP1 Proteins) activity through modulating its subcellular localization.

  6. The biochemically conserved regulatory mechanisms of recombinant DTH parallel those from mammals.

  7. maternal as well as embryonic effects on the secretion and/or functionality of Tyrosine hydroxylase (pale) may play roles in the early developmental program of the organism.

  8. activity of tyrosine hydroxylase is also increased by this interaction, in excess (show RCC1 Proteins) of the stimulation resulting from phosphorylation alone

  9. Drosophila 14-3-3/PAR-5 (show YWHAZ Proteins) is an essential mediator of PAR-1 (show F2R Proteins) function in axis formation.

  10. PAR-1 (show F2R Proteins) phosphorylates Bazooka/PAR-3 (show PARD3 Proteins) on two conserved serines to generate 14-3-3 (show YWHAZ Proteins) binding sites. This inhibits formation of the Bazooka (show PARD3 Proteins)/PAR-6 (show PARD6A Proteins)/aPKC complex by blocking Bazooka (show PARD3 Proteins) oligomerization and binding to aPKC.

Human tyrosine Hydroxylase (TH) interaction partners

  1. In high-risk metastatic Neuroblastoma (show ARHGEF16 Proteins), TH and DCX (show DCX Proteins) mRNA quantification could be used for the assessment of response to treatment and for early detection of progressive disease or relapses.

  2. the allelic frequency of the TH01 marker in 171 Swiss sudden infant death syndrome (SIDS (show IDS Proteins)) infants and 500 healthy and gender-matched Caucasian adults showed that the 9.3 allele is similarly distributed in SIDS (show IDS Proteins) cases and controls (27.2% vs. 25.6%; p-value = 0.562).

  3. This study showed that a new tyrosine hydroxylase knock-in mouse model of l-DOPA-responsive dystonia.

  4. The mutant tyrosine hydroxylase enzyme was unstable and exhibited deficient stabilization by catecholamines, leading to decline of brain tyrosine hydroxylase-immunoreactivity in the Th knock-in mice.

  5. Thus, the hTH-GFP reporter rat should be a valuable tool for Parkinson's disease research.

  6. A detailed analysis of the interaction between singly or doubly phosphorylated human tyrosine hydroxylase isoform 1(1-50) peptides and 14-3-3zeta (show YWHAZ Proteins)

  7. Study found evidence that DNA variation in the ADRA2A (show ADRA2A Proteins) gene may be causally related to ADHD-like behaviors, and for a novel association between a TH gene variant and intra-individual variability

  8. Proteomics analysis show that Ser40 of TH protein does not significantly contribute to the binding of 14-3-3gamma (show YWHAG Proteins), and rather has reduced accessibility in the TH:14-3-3gamma (show YWHAG Proteins) complex.

  9. increased expression of TH and GAP43 (show GAP43 Proteins) might be a molecular mechanism for left atrial myoelectricity remodeling of aging atrial fibrillation patients, which might be potential therapeutic targets of atrial fibrillation.

  10. Tyrosine hydroxylase polymorphisms contribute to attempted suicide in schizophrenia.

Mouse (Murine) tyrosine Hydroxylase (TH) interaction partners

  1. psychostimulants induce downregulation of DRD1a (show DRD1 Proteins) and DRD2 (show DRD2 Proteins) mRNA expression and upregulation of tyrosine hydroxylase protein expression in the testis

  2. Deletion of the CB2 r (show CNR2 Proteins) gene increased preference for and vulnerability to ethanol consumption, at least in part, by increased ethanol-induced sensitivity of the TH and mu-opioid receptor (show OPRM1 Proteins) gene expressions in mesolimbic neurons.

  3. IRBIT suppresses CaMKIIalpha activity and contributes to catecholamine homeostasis through TH phosphorylation.

  4. the presence of tyrosine hydroxylase mRNA and protein expressing cells in the striatum (including nucleus accumbens), central and medial extended amygdala during development

  5. Mating increases neuronal tyrosine hydroxylase expression and selectively gates transmission of male chemosensory information in female mice.

  6. COUP-TFI (show NR2F1 Proteins) regulates tyrosine hydroxylase expression in olfactory bulb cells through an activity-dependent mechanism involving ZIF268 (show EGR1 Proteins) induction

  7. TH-immunoreactive neurons are detected between sexes or genotypes on embryonic day 15, but a female-specific increase in TH-ir neurons is observed in CRMP4 (show DPYSL3 Proteins)-null mice on postnatal day 1 when the sex difference is not yet apparent in wild-type mice.

  8. these data reveal a powerful arcuate-NPY (show NPY Proteins)-regulated neuronal circuit that controls brown adipose tissue thermogenesis and sympathetic output via tyrosine hydroxylase neurons.

  9. TH gene silencing attenuates TH expression and catecholamine synthesis in CD4 (show CD4 Proteins)+ T lymphocytes and promotes polarization of differentiation and function towards Th1 (show HAND1 Proteins) cells.

  10. Ngb (show NGB Proteins) deficiency neither affected the level of Melanopsin (show OPN4 Proteins) and Tyrosine Hydroxylase proteins nor the intactness of PACAP (show ADCYAP1 Proteins)-positive retinohypothalamic projections in the suprachiasmatic nucleus.

Rabbit tyrosine Hydroxylase (TH) interaction partners

  1. Achilles tendon tenocytes produce tyrosine hydroxylase.

Cow (Bovine) tyrosine Hydroxylase (TH) interaction partners

  1. Retinol activates tyrosine hydroxylase via two sequential non-genomic mechanisms, which have not previously been characterized. These mechanisms are likely to operate in vivo to facilitate the stress response.

  2. IFN-alpha (show IFNA Proteins) mediated activation of ERK1/2 appeared to be responsible for the increased phosphorylation of tyrosine hydroxylase.

tyrosine Hydroxylase (TH) Protein Profile

Protein Summary

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene names and symbols associated with tyrosine Hydroxylase Proteins (TH)

  • pale (ple)
  • tyrosine 3-monooxygenase (th)
  • tyrosine 3-monooxygenase (Tsp_12013)
  • CG31196 gene product from transcript CG31196-RB (14-3-3epsilon)
  • tyrosine hydroxylase (TH)
  • tyrosine hydroxylase (Th)
  • 14-3-3 protein
  • 14-3-3 epsilon protein
  • 14-3-3-e protein
  • 14-3-3-epsilon protein
  • 14-3-3e protein
  • 14-3-3EPSILON protein
  • 14-3-3omicron protein
  • 14-3-30epsilon protein
  • 143E_DROME protein
  • 1433epsilon protein
  • anon-WO0172774.141 protein
  • anon-WO02059370.52 protein
  • CG10118 protein
  • CG31196 protein
  • CT24092 protein
  • D14-3-3e protein
  • d14-3-3epsilon protein
  • DH65B protein
  • Dmel\\CG10118 protein
  • Dmel\\CG31196 protein
  • DTH protein
  • dTH1 protein
  • dTH65B protein
  • DYT5b protein
  • DYT14 protein
  • EK3-5 protein
  • eps protein
  • l(3)j2B10 protein
  • Pale protein
  • pale/ple protein
  • par-5 protein
  • PAR5 protein
  • Ple protein
  • SR3-9 protein
  • Su(Raf)3B protein
  • th protein
  • The protein
  • TYH protein
  • VII protein

Protein level used designations for tyrosine Hydroxylase Proteins (TH)

CG10118-PA , CG10118-PB , Tyrosine-3-hydroxylase , XBB70 group VII , drosophila tyrosine hydroxylase , ple-PA , ple-PB , tyrosine hydrodroxylase , tyrosine hydroxylase , tyrosine-hydroxylase , tyrosine 3-monooxygenase , 14-3-3&epsilon , 14-3-3e , 14-3-3epsilon-PA , 14-3-3epsilon-PB , 14-3-3epsilon-PC , 14-3-3epsilon-PD , CG31196-PA , CG31196-PB , CG31196-PC , CG31196-PD , Tyrosine-3-monooxygenase , epsilon , suppressor of Ras85D 3-9 , dystonia 14 , tyrosine 3-hydroxylase

38746 Drosophila melanogaster
493867 Ciona intestinalis
10905860 Trichinella spiralis
42186 Drosophila melanogaster
7054 Homo sapiens
21823 Mus musculus
25085 Rattus norvegicus
100009362 Oryctolagus cuniculus
403444 Canis lupus familiaris
100734150 Cavia porcellus
449568 Sus scrofa
280707 Bos taurus
395592 Gallus gallus
101120619 Ovis aries
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