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anti-tyrosyl-DNA phosphodiesterase 2 (TDP2) Antibodies

TDP2 encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. Additionally we are shipping TDP2 Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TDP2 51567 O95551
TDP2 56196 Q9JJX7
TDP2 498749 Q3T1H5
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Top anti-TDP2 Antibodies at antibodies-online.com

Showing 10 out of 78 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-TTRAP Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate Sample: 1. DT40 (5x105cells)2. DT40 + rec. hTDP2 (5x105cells)3. soluble HIS-hTDP2 (5x105cells)4. pellet HIS-hTDP2 (5x105cells)Primary dilution:1:1000Secondary Antibody: dakocytomation Goat anti-rabbitSecondary dilution: 1:5000Image Submitted by: Keith CaldecottUniversity of Sussex 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Confocal immunofluorescent analysis of EAPII Antibody (C-term)(ABIN655180) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, FACS, IF, IHC (p), WB Flow cytometric analysis of A549 cells using TTRAP Antibody (C-term) Cat.-No AP51353PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of TTRAP Antibody (C-term) Cat.-No AP51353PU-N with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red). DAPI was used to stain the cell nuclear (blue). 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC, WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of TTRAP expression in transfected 293T cell line by TTRAP MaxPab polyclonal antibody.Lane 1: TTRAP transfected lysate(39.82 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to TTRAP on Hs 181.Tes cell. [antibody concentration 10 ug/ml] 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Gibbon Rabbit Un-conjugated IHC, WB 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Rabbit Un-conjugated FACS, IF, IHC, WB 400 μL Log in to see 6 Days
$457.14
Details

TDP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TDP2 Antibodies

  1. Chicken Polyclonal TDP2 Primary Antibody for IHC, WB - ABIN2777707 : Pei, Yordy, Leng, Zhao, Watson, Li: EAPII interacts with ETS1 and modulates its transcriptional function. in Oncogene 2003 (PubMed)
    Show all 2 references for ABIN2777707

  2. Human Polyclonal TDP2 Primary Antibody for EIA, FACS - ABIN955389 : Wang, Xu, Zhou, Tian, Xue, Chen, Jia: PhiC31 integrase interacts with TTRAP and inhibits NFkappaB activation. in Molecular biology reports 2010 (PubMed)
    Show all 2 references for ABIN955389

  3. Human Polyclonal TDP2 Primary Antibody for FACS, IF - ABIN655180 : Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: An approach based on a genome-wide association study reveals candidate loci for narcolepsy. in Human genetics 2010 (PubMed)
    Show all 2 references for ABIN655180

  4. Human Polyclonal TDP2 Primary Antibody for IF, WB - ABIN526818 : Thomson, Watson, Caldecott, Denneny, Depledge, Hamilton, Hopkins, Jordan, Morrow, Raoof, Waddell, Ogilvie: Generation of assays and antibodies to facilitate the study of human 5'-tyrosyl DNA phosphodiesterase. in Analytical biochemistry 2013 (PubMed)

More Antibodies against TDP2 Interaction Partners

Human tyrosyl-DNA phosphodiesterase 2 (TDP2) interaction partners

  1. Data show that DNA-repair enzyme (show LIG4 Antibodies) TDP2 knockdown in HepG2 cells significantly delays the conversion of relaxed circular DNA (RC-DNA) to covalently closed circular (ccc) DNA.

  2. This article summarizes and compares the biochemistry, functions, and post-translational regulation of TDP1 (show TDP1 Antibodies) and TDP2, as well as the relevance of TDP1 (show TDP1 Antibodies) and TDP2 as determinants of response to anticancer agents

  3. Proteolytic degradation of Top2 (show TOP2A Antibodies) enables the processing of Top2 (show TOP2A Antibodies).DNA and Top2 (show TOP2A Antibodies).RNA covalent complexes by TDP2.

  4. TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function.

  5. Mutations in the 5'-tyrosyl-DNA phosphodiesterase activity of TTRAP,in particular TTRAP(E152A), showed decreased inhibitory activity on cell growth.

  6. Magnesium is indispensable for a 5'-tyrosyl DNA phosphodiesterase activity.

  7. VPg unlinkase activity in different mammalian cell lines correlates with their differential expression of TDP2.

  8. Biochemical characterization of human tyrosyl-DNA phosphodiesterase 2 (TDP2/TTRAP): a Mg(2 (show MUC7 Antibodies)+)/Mn(2+)-dependent phosphodiesterase specific for the repair of topoisomerase cleavage complexes.

  9. findings suggest a previously unidentified function for TTRAP and nucleolar cavities in ribosome biogenesis under stress.

  10. both FOXP2 (show FOXP2 Antibodies) and KIAA0319 (show KIAA0319 Antibodies)/TTRAP/THEM2 (show ACOT13 Antibodies) genes play an important role in human language development, but probably through different cerebral pathways.

Mouse (Murine) tyrosyl-DNA phosphodiesterase 2 (TDP2) interaction partners

  1. our data reveal TDP2-mediated error-free NHEJ as an efficient and accurate mechanism to repair TOP2 (show TOP2 Antibodies)-induced DSBs

  2. Evidence implicates Tdp2 in the repair of Top1 (show TOP1 Antibodies)-mediated DNA damage in cultured cells and in vivo, in the absence of Tdp1 (show TDP1 Antibodies).

  3. the protein associates with TGF-beta (show TGFB1 Antibodies) receptors and components of the TRAF6 (show TRAF6 Antibodies)-TAK1 (show NR2C2 Antibodies) signaling module

Zebrafish tyrosyl-DNA phosphodiesterase 2 (TDP2) interaction partners

  1. although the role of Smad (show SMAD1 Antibodies) proteins in mediating Nodal signaling is well-documented, the functional characterization of Ttrap provides insight into a novel Smad (show SMAD1 Antibodies) partner that plays an essential role in the fine-tuning of this signal transduction cascade

TDP2 Antigen Profile

Protein Summary

This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.

Gene names and symbols associated with TDP2

  • tyrosyl-DNA phosphodiesterase 2 (TDP2) antibody
  • tyrosyl-DNA phosphodiesterase 2 (tdp2) antibody
  • tyrosyl-DNA phosphodiesterase 2 (Tdp2) antibody
  • tyrosyl-DNA phosphodiesterase 2b (tdp2b) antibody
  • ad022 antibody
  • D13Ertd656e antibody
  • dJ30M3.3 antibody
  • eap2 antibody
  • EAPII antibody
  • hTDP2 antibody
  • tdp2 antibody
  • Ttrap antibody
  • ttrapl antibody

Protein level used designations for TDP2

5'-Tyr-DNA phosphodiesterase , 5'-tyrosyl-DNA phosphodiesterase , ETS1-associated protein 2 , ETS1-associated protein II , TRAF and TNF receptor associated protein , TRAF and TNF receptor-associated protein , VPg unlinkase , tyr-DNA phosphodiesterase 2 , tyrosyl-RNA phosphodiesterase , TRAF and TNF receptor-associated protein homolog , Tyr-DNA phosphodiesterase 2 , Traf and Tnf receptor associated protein , immune transcriptional repressor , traf and tnf receptor associated protein, like , tyrosyl-DNA phosphodiesterase 2

GENE ID SPECIES
51567 Homo sapiens
100049743 Xenopus laevis
421007 Gallus gallus
507579 Bos taurus
56196 Mus musculus
498749 Rattus norvegicus
553516 Danio rerio
Selected quality suppliers for anti-TDP2 (TDP2) Antibodies
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