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tyrosyl-DNA phosphodiesterase 2 Proteins (TDP2)

TDP2 encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. Additionally we are shipping TDP2 Antibodies (68) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TDP2 51567 O95551
TDP2 56196 Q9JJX7
TDP2 498749 Q3T1H5
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Top TDP2 Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,995.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,001.17
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,017.67
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$3,023.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$498.21
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TDP2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)
Rat (Rattus) ,

Top referenced TDP2 Proteins

  1. Human TDP2 Protein expressed in Escherichia coli (E. coli) - ABIN1098575 : Pinel, Fauchereau, Moreno, Barbot, Lathrop, Zelenika, Le Bihan, Poline, Bourgeron, Dehaene: Genetic variants of FOXP2 and KIAA0319/TTRAP/THEM2 locus are associated with altered brain activation in distinct language-related regions. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2012 (PubMed)
    Show all 2 references for ABIN1098575

More Proteins for tyrosyl-DNA phosphodiesterase 2 (TDP2) Interaction Partners

Human tyrosyl-DNA phosphodiesterase 2 (TDP2) interaction partners

  1. Data show that DNA-repair enzyme (show LIG4 Proteins) TDP2 knockdown in HepG2 cells significantly delays the conversion of relaxed circular DNA (RC-DNA) to covalently closed circular (ccc) DNA.

  2. This article summarizes and compares the biochemistry, functions, and post-translational regulation of TDP1 (show TDP1 Proteins) and TDP2, as well as the relevance of TDP1 (show TDP1 Proteins) and TDP2 as determinants of response to anticancer agents

  3. Proteolytic degradation of Top2 (show TOP2A Proteins) enables the processing of Top2 (show TOP2A Proteins).DNA and Top2 (show TOP2A Proteins).RNA covalent complexes by TDP2.

  4. TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function.

  5. Mutations in the 5'-tyrosyl-DNA phosphodiesterase activity of TTRAP,in particular TTRAP(E152A), showed decreased inhibitory activity on cell growth.

  6. Magnesium is indispensable for a 5'-tyrosyl DNA phosphodiesterase activity.

  7. VPg unlinkase activity in different mammalian cell lines correlates with their differential expression of TDP2.

  8. Biochemical characterization of human tyrosyl-DNA phosphodiesterase 2 (TDP2/TTRAP): a Mg(2 (show MUC7 Proteins)+)/Mn(2+)-dependent phosphodiesterase specific for the repair of topoisomerase cleavage complexes.

  9. findings suggest a previously unidentified function for TTRAP and nucleolar cavities in ribosome biogenesis under stress.

  10. both FOXP2 (show FOXP2 Proteins) and KIAA0319 (show KIAA0319 Proteins)/TTRAP/THEM2 (show ACOT13 Proteins) genes play an important role in human language development, but probably through different cerebral pathways.

Mouse (Murine) tyrosyl-DNA phosphodiesterase 2 (TDP2) interaction partners

  1. our data reveal TDP2-mediated error-free NHEJ as an efficient and accurate mechanism to repair TOP2 (show TOP2 Proteins)-induced DSBs

  2. Evidence implicates Tdp2 in the repair of Top1 (show TOP1 Proteins)-mediated DNA damage in cultured cells and in vivo, in the absence of Tdp1 (show TDP1 Proteins).

  3. the protein associates with TGF-beta (show TGFB1 Proteins) receptors and components of the TRAF6 (show TRAF6 Proteins)-TAK1 (show NR2C2 Proteins) signaling module

Zebrafish tyrosyl-DNA phosphodiesterase 2 (TDP2) interaction partners

  1. although the role of Smad (show SMAD1 Proteins) proteins in mediating Nodal signaling is well-documented, the functional characterization of Ttrap provides insight into a novel Smad (show SMAD1 Proteins) partner that plays an essential role in the fine-tuning of this signal transduction cascade

TDP2 Protein Profile

Protein Summary

This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.

Gene names and symbols associated with TDP2

  • tyrosyl-DNA phosphodiesterase 2 (TDP2)
  • tyrosyl-DNA phosphodiesterase 2 (tdp2)
  • tyrosyl-DNA phosphodiesterase 2 (Tdp2)
  • tyrosyl-DNA phosphodiesterase 2b (tdp2b)
  • ad022 protein
  • D13Ertd656e protein
  • dJ30M3.3 protein
  • eap2 protein
  • EAPII protein
  • hTDP2 protein
  • tdp2 protein
  • Ttrap protein
  • ttrapl protein

Protein level used designations for TDP2

5'-Tyr-DNA phosphodiesterase , 5'-tyrosyl-DNA phosphodiesterase , ETS1-associated protein 2 , ETS1-associated protein II , TRAF and TNF receptor associated protein , TRAF and TNF receptor-associated protein , VPg unlinkase , tyr-DNA phosphodiesterase 2 , tyrosyl-RNA phosphodiesterase , TRAF and TNF receptor-associated protein homolog , Tyr-DNA phosphodiesterase 2 , Traf and Tnf receptor associated protein , immune transcriptional repressor , traf and tnf receptor associated protein, like , tyrosyl-DNA phosphodiesterase 2

GENE ID SPECIES
51567 Homo sapiens
100049743 Xenopus laevis
421007 Gallus gallus
507579 Bos taurus
56196 Mus musculus
498749 Rattus norvegicus
553516 Danio rerio
Selected quality suppliers for TDP2 Proteins (TDP2)
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