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tyrosylprotein Sulfotransferase 2 Proteins (TPST2)

The protein encoded by TPST2 catalyzes the O-sulfation of tyrosine residues within acidic regions of proteins. Additionally we are shipping TPST2 Antibodies (59) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TPST2 22022  
TPST2 8459 O60704
Rat TPST2 TPST2 288719 Q5RJS8
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Top TPST2 Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$3,036.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,036.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TPST2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , ,
, ,

More Proteins for tyrosylprotein Sulfotransferase 2 (TPST2) Interaction Partners

Mouse (Murine) tyrosylprotein Sulfotransferase 2 (TPST2) interaction partners

  1. cerebral abnormalities in grt/grt Tpst2 gene defect mice are characterized by cortical hypoplasia at the frontooccipital axis with immature pyramidal neurons and insufficient development of callosal fibers

  2. Findings indicate that low body weight and salivary gland hypofunction in Tpst2-/- mice is due solely to primary hypothyroidism.

  3. Results demonstrate the importance of protein-tyrosine sulfation for proper development of the retina and suggest different phenotypes resulting from elimination of TPST-1 (show TPST1 Proteins) or -2 may reflect differential expression patterns or levels of the enzymes.

  4. Data show that Tpst1 (show TPST1 Proteins)/Tpst2 DKO leukocytes bound less P-selectin (show SELP Proteins) than wild type leukocytes despite equivalent surface expression of Psgl-1 (show SELPLG Proteins).

  5. Lack of tyrosylprotein sulfotransferase-2 activity results in altered sperm-egg interactions and loss of ADAM3 and ADAM6 in epididymal sperm.

  6. These results indicate that protein-tyrosine sulfation by Tpst1 (show TPST1 Proteins)/2 is essential for proper outer segment morphogenesis and synaptic function, but is not critical for overall retinal structure or synapse formation.

  7. demonstrated that the Tpst2 transgene rescues the mutant phenotypes both in vitro and in vivo

  8. Considering that Tpst2 is the responsible gene of grt mice, mutation of which is associated with a poor function of TSH receptor (show TSHR Proteins), the findings raise the possibility of involvement of factors including Tpst2 in the insulin (show INS Proteins) hyposecretion in grt mice.

  9. results demonstrate conclusively that TPST-1 (show TPST1 Proteins) and TPST-2 have distinct biological roels in vivo and document for the first time the critical importance of protein-tyrosine O-sulfation in male fertility

  10. The growth-retarded (grt) mutation leads to a loss of TPST2 activity, and TPST2 isoform has a high degree of substrate preference for TSH receptor (TSHR (show TSHR Proteins)).

Human tyrosylprotein Sulfotransferase 2 (TPST2) interaction partners

  1. Using a quantum mechanics protocol of alanine scanning, the study identified unequivocally the role of the amino acids involved in the TPST-2 catalytic mechanism.

  2. the first crystal structure of the human tyrosylprotein sulfotransferase isoform 2 complexed with a substrate peptide (C4P5Y3) derived from complement C4 and 3'-phosphoadenosine-5'-phosphate at 1.9 A resolution, is reported.

  3. Shear stress-dependent upregulation of TPST2 in human endothelium is mediated by a tyrosine kinase (show TXK Proteins)-dependent pathway

  4. Tyrosine sulfation of CCR5 N-terminal peptide follows a discrete pattern and temporal sequence

  5. The kinetic parameters of tyrosylprotein sulfotransferase-1 (show TPST1 Proteins) and -2, catalyzing tyrosine sulfation of CCR8 (show CCR8 Proteins) peptides, were determined using liquid chromatography electrospray ionisation mass spectrometry.

Cow (Bovine) tyrosylprotein Sulfotransferase 2 (TPST2) interaction partners

TPST2 Protein Profile

Protein Summary

The protein encoded by this gene catalyzes the O-sulfation of tyrosine residues within acidic regions of proteins. The encoded protein is a type II integral membrane protein found in the Golgi body. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with TPST2

  • tyrosylprotein sulfotransferase 2 (tpst2)
  • tyrosylprotein sulfotransferase 2 (TPST2)
  • tyrosylprotein sulfotransferase 2 (LOC100224714)
  • tyrosylprotein sulfotransferase 2 (LOC100338693)
  • protein-tyrosine sulfotransferase 2 (Tpst2)
  • tyrosylprotein sulfotransferase 2 (Tpst2)
  • AI448750 protein
  • D5Ucla3 protein
  • grm protein
  • grt protein
  • TANGO13B protein
  • zgc:64196 protein

Protein level used designations for TPST2

protein-tyrosine sulfotransferase 2 , tyrosylprotein sulfotransferase 2 , TPST-2 , tyrosylprotein sulfotransferase-2 , transport and golgi organization 13 homolog B , tyrosylprotein phosphotransferase 2

GENE ID SPECIES
393391 Danio rerio
458726 Pan troglodytes
495291 Xenopus laevis
549785 Xenopus (Silurana) tropicalis
100606069 Nomascus leucogenys
100224714 Taeniopygia guttata
100338693 Oryctolagus cuniculus
22022 Mus musculus
8459 Homo sapiens
288719 Rattus norvegicus
540183 Bos taurus
416910 Gallus gallus
486332 Canis lupus familiaris
100154448 Sus scrofa
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