Z-VEID-FMK
| Application |
Functional Studies (Func), Cell Culture (CC)
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1 reference available |
| Catalog no. | ABIN412080 |
| Quantity |
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| Price | 258.50 $ Plus shipping costs $45.00 |
| Shipping to |
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| Availability | Will be delivered in 2 to 3 Business Days |
Additional Information
| Immunogen | Sequence: Z-Val-Glu(OMe)-Ile-Asp(OME)-FMK |
| Sequence | Z-Val-E(OMe)-Ile-Asp(OMe)-FMK |
| Format | Lyophilized |
| Description | VEID is the specific recognition sequence for caspase-6/Mch2. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups). |
| Characteristics | Molecular formula: C₃₁H₄₅FN₄O₁₀ |
| Molecular Weight | 652.9 Da |
Application Details
| Application Notes | We recommend using 2-10 μ M for inhibiting caspase activity in cell culture. The optimal doses may vary for different cells and culture conditions. |
| Handling Advice | Protect from light and moisture |
| Purity | Single spot by TLC |
| Buffer | 1 mg (or 5 mg) lyophilized powder |
| Storage | -20°C |
| Expiry Date | 12 months |
| Restrictions | For Research Use only |
Publications
| Product |
Ariazi, Cunliffe, Lewis-Wambi et al.: "Estrogen induces apoptosis in estrogen deprivation-resistant breast cancer through stress responses as identified by global gene expression across time." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 47, pp. 18879-86, 2011 (PubMed).
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